The drug "Pimafucin" is available in the form of vaginal suppositories, tablets and ointments. It is an antifungal agent with a wide spectrum of action. It is intended for the treatment of diseases of the organs of the reproductive system of women, which provoke yeast-like fungi. In reviews of Pimafucin tablets for thrush, they are called number one choice.
The drug shows maximum effectiveness against candidiasis. Therefore, doctors begin the treatment of thrush with the appointment of this remedy. The principle of action of the drug is to use pronounced fungicidal properties. Its active substance violates the integrity of pathogenic membranes and destroys microorganisms. The maximum resistance to Pimafucin suppositories, reviews and instructions confirm this, show dermatophytes.
Appointment
Most often, the medication is prescribed for the treatment of skin and mucous membranes affected by fungal infections of various types. Its use is also justified in the treatment of candidiasis. The tool is practically not absorbed from the gastrointestinal tract, from the surface of the skin and mucous membranes. Short list of indications:
- fungal lesions of the nail plates;
- trichomoniasis;
- inflammation of the vulva;
- vaginitis;
- otomycosis;
- dermatological candidiasis.
Oral form
In the reviews and instructions for the use of Pimafucin tablets, it is said that the product showed excellent results in the treatment and prevention of colonization of the intestines by fungi of the candida family. Their uncontrolled reproduction provokes prolonged use of antibiotics, hormonal drugs containing corticosteroids, cytostatics.
The cost of a package of 20 enteric-coated tablets in pharmacies is approximately 600 rubles.
Mild dosage form
The cream is prescribed to patients suffering from candidiasis of skin and mucous tissues. And also in cases of defeat by dermatophytes and other yeast-like fungi. The reviews of Pimafucin cream say that the average cost of the drug in Russian pharmacies is 360 rubles. The drug is supplied in metal tubes. Cream weight - 30 g.
Suppositories
The main indication for taking suppositories is an infectious and fungal infection of the vulva. They are produced in two configurations. One is designed for short-term treatment of thrush and involves a set of three suppositories, packed in a cardboard box. Its price is 300 rubles.
In the reviews and instructions for the use of Pimafucin suppositories, it is said that in the treatment of neglected vulvitis and vaginitis of fungal origin, it is advisable to purchase a second set. It consists of six suppositories. The cost of the set is 520 rubles.
Dosage selection
In inflammatory processes caused by yeast-like fungi in the vulva and vagina, prescribe the use of one suppository for six days. In some cases, the use of the drug is allowed for nine days. To insert a candle into the vagina as deep as possible, you need to take a horizontal position and relax.
In the reviews on the use of candles "Pimafucin" they say that the standard prescription scheme is not always effective. In this case, the treatment may be supplemented with an oral form. Four tablets are drunk per day. The oral form is responsible for the sanitation of the internal surface of the intestine, which can also serve as a focal point for the colonization of yeast-like fungi.
The duration of the therapeutic course is ten days. To enhance the effect of therapeutic measures, a mild form of the drug is prescribed. The instructions and reviews about the ointment "Pimafucin" claim that it has proved its effectiveness in the destruction of fungal infections of the skin of the genital organs of the partner. The cream is applied once or several times a day.
Balanoposthitis
As part of the drug therapy of the disease, the use of ointment is widespread. She lubricated areas of the skin that underwent colonization of fungi. The procedure is performed once a day. Possible increase in dosage. Instructions and reviews on "Pimafucin" in the form of a cream prove the high effectiveness of the drug.
Damage to intestinal tissues
Thrush of the organs of the excretory system is treated with the oral form of the medication. Adults are advised to take four tablets every day. The duration of treatment is seven days. For children, the dose is halved. They need to take two pills. In reviews of Pimafucin, women give high marks to the results of treatment. They report the absence of side effects and well-being during the therapeutic course.
Mycosis of the skin
With a dermatological lesion, a mild form of the drug is used. The ointment is applied to the affected area of ​​the skin once a day. If necessary, the number of procedures can be increased. In the reviews of women about Pimafucin, it is mentioned that this remedy has found application in pediatric practice. It is used to treat diaper rash in infants.
Otomycosis
Fungal damage to the organs of the ear is subject to therapy with natamycin, the main active ingredient in the mild form of Pimafucin. With open access to the affected areas, they are regularly lubricated with ointment. The instructions and reviews about "Pimafucin" recommend a preliminary cleaning of the auricle. A tampon is used to administer the drug to the middle section. Its surface is abundantly lubricated with cream and carefully introduced into the ear canal.
The duration of therapy is set individually. Do not stop treatment after the disappearance of the main symptoms. The reviews on the use of “Pimafucin” say that the best results are achieved when patients used the ointment for several days after the complete disappearance of the pathological manifestations of the underlying disease.
Reception during pregnancy
The tool is recommended by leading obstetricians and gynecologists for the treatment of thrush during the period of gestation and breastfeeding. The dosage of the drug is indicated by the attending physician. To date, this medication is included in the first choice group in the treatment of mucosal and skin lesions with fungal infections in pregnant women and during lactation. Judging by the reviews, "Pimafucin" in the first trimester is taken by every second woman.
Side effects
Despite the good tolerability of the drug by patients, the following negative manifestations were recorded by doctors:
- burning in the vagina and on the skin;
- diarrhea;
- bouts of nausea.
All the side effects listed above do not require special treatment and do not lead to drug withdrawal. They go away on their own a few days after the start of a therapeutic course.
Contraindications
The main obstacle to treatment may be individual intolerance to the active component. In this case, we are talking about natamycin. Another contraindication, which is indicated in the instructions for use of Pimafucin tablets and in the reviews, is porphyria.
Special cases
A uniform distribution of natamycin contained in suppositories on the inner surface of the vagina is ensured by foaming of auxiliary substances under the influence of natural body temperature. In some cases, this drug may be included in the complex treatment plan for dermatomycoses of various genesis.
Burning and irritation of the vaginal mucosa that appear during the use of suppositories arise due to the cetyl alcohol added to the preparation . In the composition of the drug, its proportion is insignificant, but sensitive patients may feel tingling and dryness. This is stated in the reviews of the candles "Pimafucin."
If a fungal infection recurs after a certain period of time after the use of suppositories, then the appointment of an oral form of natamycin is recommended. During menstruation, candles are not used, since their effectiveness is minimal. During the course of the therapeutic course, partners are advised to use barrier contraception and undergo a thorough examination by specialized specialists.
Women who use suppositories do not need to give up sex. The safety of the active substance is proven. Therefore, natamycin is prescribed for the treatment of newborns. In reviews of Pimafucin suppositories, young parents mention that pediatricians prescribed this drug to their children.
Storage rules
All forms of the drug should be kept in dry rooms. Recommended warehouse air temperature varies between 15-25 ° C. The shelf life of the oral and mild forms of the medicinal product as determined by the manufacturer of Temmler Italy S.R.L. is four years.
Suppositories should be used after twenty-four months. The instructions and reviews on the use of "Pimafucin" say that when the storage temperature is exceeded, the candles are destroyed. Suppositories foam. Their shape is changing.
Composition of the tablets
The list of components:
- 100 mg natamycin;
- 80 mg potato starch;
- 5 mg of PVP;
- 2.5 mg magnesium stearate;
- 66 mg of lactose;
- 3 mg of gelatin;
- 7 mg gum arabic;
- 30 mg of calcium carbonate;
- 14 mg of taolin;
- 21 mg of talc;
- 18 mg phthalate;
- 122 mg sucrose.
Excipients:
- methyl p-hydroxybenzoate;
- triacetin;
- beeswax.
The composition of vaginal suppositories
The main components:
- 700 mg of fat;
- 100 mg natamycin
- 460 mg sorbitol;
- 690 mg of cetyl alcohol.
Excipients:
- polysorbate;
- sodium bicarbonate;
- adipic acid.
The composition of the soft form
The main components:
- 20 mg natamycin;
- 100 mg decyl oleate;
- 135 mg cetostearyl alcohol;
- 150 mg propylene glycol.
Excipients:
- wax;
- sodium lauryl sulfate.
Patient Reviews
The reviews and instructions for the use of "Pimafucin" mean that the therapeutic course is not generally associated with the appearance of side effects. The treatment is effective. Patients highlight the following benefits of using this medication:
- proven safety;
- almost complete absence of contraindications;
- availability;
- over-the-counter sales;
- an abundance of analogues;
- prompt disposal of thrush;
- the possibility of use during pregnancy and breastfeeding.
Analogs
Drugs that contain natamycin:
Primafungin
Primafungin is manufactured by the pharmaceutical company OAO Aveksima (Russian Federation). Suppositories are packed in a cardboard box of three pieces. The dosage of this drug is fully consistent with the instructions listed in the instructions for use of Pimafucin. Customer reviews confirm this.
One candle contains 100 mg of natamycin. The drug has virtually no systemic effect on the body. If during use a pronounced burning sensation appears, you should abandon the use of this tool and seek additional advice from your doctor.
Primafungin is sold in pharmacies without a prescription. Its price is about 200 rubles. List of indications:
- inflammation of the vulva;
- vaginitis, regardless of etiology;
- damage to the skin and mucous membranes of the candida family fungi.
- The medication is approved for use during lactation and pregnancy.
Pimafukort
This drug is considered an analogue of Pimafucin. The reviews and instructions say that it also includes neomycin and hydrocortisone. These components provide a comprehensive therapeutic effect. The drug is manufactured by the Italian pharmaceutical company Temmler Italy S.R.L.
According to the manufacturer’s description, this product has a pronounced anti-inflammatory effect. It perfectly fights fungal infections of the skin and mucous membranes. Used externally. Packed in cardboard boxes. The metal tube contains 15 g of cream.
"Pimafucort" is not a complete analogue of "Pimafucin", instructions for use, mentioned in reviews, differs. It says that the level of absorption of hydrocortisone through the skin without wound lesions is three percent. In violation of the integrity of the epidermis, this value doubles. If there is an infection on the skin, the degree of absorption reaches 15%.
When using Pimafucort in the treatment of children, it should be borne in mind that their susceptibility is higher than that of adults. The older the child, the lower the absorption rate. There are few side effects. In reviews of Pimafucin and Pimafucort, some patients with sensitive skin insist that they feel a pronounced burning sensation and dryness of the integument on which the ointment was applied. Local redness was noted. Sometimes women complained of itching.
If you note one of the above actions associated with taking Pimafucort, then we are talking about the manifestation of allergic reactions. In this case, the therapeutic course is canceled, and the drug must be replaced. True, usually these symptoms subside on the third day of using the cream. Similar moments are described by patients in their reviews of Pimafucin.
With prolonged use of the cream in children, the syndrome of suppression of the action of the adrenal cortex is diagnosed. A similar reaction is rare and only in those patients who applied occlusive dressings and applied the product to large areas of the skin.
Instructions for use
When using Pimafucort in the eyelids, you need to remember about the possibility of increasing intraocular pressure, which can lead to further development of cataracts. In the therapeutic treatment of open wound surfaces, the risk of toxic effects is allowed. The reviews of Pimafucin, available in mild form, indicate the safety of the drug for children.
Pimafukort can also be used in pediatrics, but under the supervision of a physician. The list of indications includes all kinds of dermatoses, complications after infection with fungal and bacterial infections. Contraindications include juvenile acne, anogenital itching, allergic reactions to the introduction of vaccines of an allergic nature. Do not use the cream for ichthyosis, the presence of open wound surfaces, viral diseases of the epidermis.
Pimafukort is prescribed with caution to children under one year of age. And in the instructions, reviews about "Pimafucin" confirm this, there is no such limitation. The interaction of Pimafucort with other drugs is not described. Cross-type hypersensitivity was recorded when using neomycin with paromomycin, kanamycin, aminoglycosoid, gentamicin.
Dosage
For adults and adolescents, the cream is applied twice a day. The course of treatment should not exceed fourteen days. Ointment "Pimafukort" - the number one choice for the treatment of dermatoses. Occlusive dressings are contraindicated in young children. No drug overdose was detected.
Doctors admit the possibility of toxic effects when applying cream to the surface of the middle part of the ear, provided that the integrity of the eardrum is damaged. In this case, recommend Pimafucin. User reviews confirm no side effects. To enhance the effect of exposure, other forms of the drug are used.
Natamycin
This drug is considered one of the most effective antibiotics aimed at combating fungal infections. Most often, this remedy is prescribed for the treatment of thrush. In pharmacies, it is represented by suppositories, oral and soft forms. Like Pimafucin tablets, reviews say that Natamycin rarely causes side effects. It is almost non-toxic, therefore it is indicated for the treatment of pregnant women. The number of contraindications is minimal.
Instructions for use
The drug belongs to the group of tetraenes. Its main property is aimed at the destruction of fungal infections. Almost all known pathogenic organisms of a similar origin fall under the spectrum of its action. Like Pimafucin tablets, reviews of which are recommendatory in nature, Natamycin is prescribed by a doctor.
The main active ingredient is natamycin. It is produced by actinomycete production. The drug breaks the membrane cells of the pathogenic flora of yeast and similar fungi, dermatomycetes and trichomonads. Gram-positive cells show resistance to this medication.
Natamycin is manufactured by Russian, European and Asian pharmaceutical companies. The antibiotic is sensitive to sunlight, so it is packaged in a dark opaque container. The active substance natamycin is not soluble in water. It is made in the form of a powder, which has a yellowish or white color. It is soluble in acetic acid, cooled to the lowest possible temperature, and in dimethylformamide.
If necessary, natamycin can be diluted with methyl alcohol. Like Pimafucin tablets, the instructions and patient reviews confirm this, it does not have a systemic effect on the body. The substance is not absorbed from the gastrointestinal tract and from the surface of the skin."Natamycin" is not prescribed to patients who suffer from tuberculosis. Avoid the use of the medication to people with individual intolerance to medicinal components.
Side effects of Natamycin
Doctors note the presence of adverse effects that may be associated with the use of the drug:
- diarrhea of ​​varying severity;
- vomiting
- nausea;
- burning;
- itching
- dryness.
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Thrush treatment
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- "Flucostat";
- «-»;
- «-OBL»;
- «-»;
- Diflucan
- "Mikosist";
- "Diflason."
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«». – 1 . . – 200 . 360 . – . «» 50 . Excipients:
- sodium lauryl sulfate;
- lactose;
- ;
- magnesium stearate;
- aerosil;
- gelatin;
- ;
- ;
- titanium dioxide.
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The following pathological conditions may occur during patients taking the medicine:
- headache in various locations;
- cramps
- dizziness;
- nausea;
- leukopenia;
- ventricular flutter;
- thrombocytopenia;
- agranulocytosis;
- skin rash;
- anaphylactic shock;
- alopecia;
- erythema;
- necrolysis;
- violation of the urinary system.
Basic information about Flucostat
The drug is sold in pharmacies without a prescription. It is prescribed for the treatment of cryptococcosis and candidiasis. Also used to prevent bacterial infections in patients with AIDS. The tool has a lot of contraindications:
- renal failure;
- hepatic dysfunction;
- combined intake with homeopathic medicines;
- alcohol addiction;
- organic disease remedies;
- pathological changes in electrolyte balance.
Fluconazole
This medicine is produced by many international and Russian pharmacological companies. Estimated price is 280 rubles. It contains 50 mg of fluconazole. The active substance is excreted in a volume of 80%. The drug is sold in the pharmacy network upon presentation of the prescription.
Indications:
- cryptococcal meningitis;
- epidermal fungal infections;
- candidiasis of various origins.
Contraindications:
- children under 16 years old;
- individual intolerance;
- lactation;
- taking cisapride;
- lactase deficiency;
- use of terfenadine;
- congenital cardiac abnormalities.
Diflucan
This medicine is produced by the world famous French company Pfizer. It is also an effective antifungal agent that is aimed at treating thrush. The main component is fluconazole. Packages may contain 12, 7 or 4 capsules.
Mikosist
The medicine is sold in cardboard boxes. They enclosed 4 capsules. The producer is the Russian branch of the Gideon Richter concern. Estimated cost - 730 rubles. The composition of the drug contains 150 mg of the active substance. It is released according to the prescription of the attending physician.
Indications:
- cryptoccosis;
- candidiasis;
- fungal infections.
- Contraindications:
- lactation;
- the use of astemizole;
- lactose deficiency.
"Diflason"
This prescription drug is produced by the company Vector-Pharm LLC, which is based in Slovenia. Available in 100 ml glass vials. Recommended storage temperature is 20 ° C. An effective antifungal drug intended for infusion. As auxiliary substances, an aqueous solution of sodium chloride is used.
Side effects:
- headache;
- cramps
- neutropenia;
- cardiac abnormalities;
- swelling of the face;
- skin rash;
- itching
- necrolysis.
Wagisept
The composition of the drug is fluconazole and metronidazole. The medicine is produced in Russia by Firn-M. The drug is dispensed by prescription. Estimated cost is 350 rubles. A cardboard pack contains ten vaginal suppositories.
Safocide
A pack of 12 tablets of the drug is sold at a price of 1681 rubles. Manufacturer - Nizhpharm JSC (Russia). There are Indian counterparts. In addition to fluconazole, the drug includes the antibiotic azithromycin, secnidazole.
Since “Safocide” is a set of individual tablets, the set of ingredients for each is different.
Indications:
- various infections of the genitourinary system;
- trichomoniasis;
- urethritis;
- cervicitis;
- gonorrhea;
- vaginosis of bacterial origin;
- cystitis;
- inflammation of the tissues of the vulva;
- vaginitis.