Our body has a perfect system for supplying tissue with oxygen through red blood cells. A huge role in this is heme iron. With a decrease in its reserves in the body, additional medical assistance may be required. For this, drugs that contain iron sulfate and ascorbic acid are used.
Characteristic
Integrated drug. Iron makes up for its deficiency in the body, and vitamin C improves its absorption from the stomach and intestines.
Form release of iron sulfate with ascorbic acid:
- pills - 50 pieces per pack;
- dragees - 100 pieces.
Absorption and bioavailability of iron are high. It is absorbed, as a rule, in the duodenum.
Trade names for iron sulfate with ascorbic acid: "Sorbifer Durules", "Ferroplex", "Tardiferon".
Pharmacological properties
Binding to blood proteins - ninety percent or more. It accumulates in the cells of the liver parenchyma and phagocytic macrophages, a small amount in the form of myoglobin in the muscles. The half-life is six hours.
Indications
According to the instructions, the drug is prescribed if certain conditions appear in the human body:
- Iron-deficiency anemia.
- Pregnancy.
- Lactation.
- Prolonged bleeding.
- Stomach ulcer.
- Deterioration of iron absorption in chronic diarrhea.
- Improper nutrition.
Contraindications and side effects
Iron sulfate plus ascorbic acid is contraindicated in the following ailments:
- Excessive Sensitivity.
- Increased iron concentration in the body.
- Excessive deposition of hemosiderin in the tissues of the body.
- Hereditary disease, which manifests itself as a violation of iron metabolism with further accumulation in tissues.
- Hereditary or acquired pathological process of hematopoiesis, which is caused by damage to the bone marrow.
- Condition after gastrectomy.
- Bleeding.
- Children's age (up to six or up to twelve years, depending on the manufacturer).
According to the instructions for use, the drug must be carefully taken for inflammatory lesions of the mucous membrane of the small intestine, as well as damage to one or more herniform protrusions of the walls of the large or small intestine and non-infectious damage to the digestive system.
It is possible to use the medication in an "interesting position" and during breastfeeding for serious reasons.
The drug can cause certain negative manifestations, such as:
- Vomiting.
- Intestinal obstruction.
- Loss of appetite.
- Diarrhea.
- Nausea.
- Allergic rashes on the skin.
- Fatigue.
- The accumulation of excess heat in the body.
- Burning sensation.
If signs of poisoning occur, you should immediately contact a medical specialist. In addition, you need to rinse the stomach, and also introduced "Deferoxamine". Then carry out symptomatic therapy.
The medication is effective only for hematological syndrome, which is characterized by a violation of hemoglobin synthesis as a result of a deficiency and is ineffective in anemia of a different origin.
Staining of feces in a dark color when using iron-containing medications is not dangerous. Before using the medicine, a blood test must be done.
How to take iron sulfate with ascorbic acid
Dragees and tablets are used for oral use, thirty minutes before eating, washed down with water. After stabilization of the hemoglobin level, therapy is carried out for one to three months until complete accumulation of iron in the body.
The standard dosage of iron and ascorbic acid for people during therapy is from one hundred to two hundred milligrams per day, with maintenance treatment - one hundred milligrams per day. For small patients, three milligrams per kilogram of weight per day.
According to the instructions for use "Sorbifer durules", it is known that adult patients are prescribed six tablets per day. With anemia in the first and second trimesters of an "interesting position" - one tablet once a day, in the last three months and during breastfeeding it is recommended to use 1 tablet twice a day.
"Tardiferon" is suitable for eliminating iron deficiency anemia in adults and children from ten years old - two tablets per day one hour before a meal; children from six years old - half a tablet per day.
Women in the prophylactic position are recommended to use one tablet at a time interval of 24 hours in the second and third trimesters.
"Ferroplex" is prescribed for adults in 2 tablets three times a day, small patients are recommended to use the same amount of the drug.
Does iron and ascorbic acid interact with other medicines
According to the instructions, when the medicine is combined with Tetracycline, tea, as well as egg yolk, a mutual decrease in absorption occurs. Antacids reduce the absorption of drugs with iron.
In addition, combination with other iron-containing agents should be avoided, since there is a risk of an overdose.
According to the drug annotation, it is known that iron sulfate with ascorbic acid can lower the absorption of the simultaneously used Enoxacin, Clodronate, Grepafloxacin, Methyldopa and endocrine hormones.
It is not recommended to combine with the following medicines: Ofloxacin, Ciprofloxacin, Norfloxacin.