In the article, we will consider the instructions and reviews for the drug "Dramina".
It is intended to eliminate the symptoms of airborne and marine diseases. It is used in cases where nausea and vomiting occur in the transport, as well as dizziness. "Dramina" has a small sedative effect. The drug is widely used during travel as an aid to motion sickness and other negative manifestations.
Structure
According to the instructions, "Dramina" is produced in a single dosage - 50 mg. Packed tablets in packs of 5 and 10 pieces. Packaging is completed with detailed instructions.
The tablets are round and flat in white. The active component of the drug is dimenhydrinate. The composition is also supplemented with auxiliary substances:
- Lactose Monohydrate.
- Microcrystalline cellulose.
- Magnesium stearate.
- Povidone.
- Crospovidone.
Dimenhydrinate has a pronounced therapeutic effect. It is this substance that allows you to eliminate unwanted symptoms of exposure to the vestibular apparatus. Excipients can increase the digestibility of tablets, which increases their effectiveness.
The properties
As indicated in the instructions, "Dramina" is an inhibitor of histamine H1 receptors and M-cholinergic receptors in the central nervous system. Absorption of the active substance occurs in the stomach and intestines. The peak effectiveness of the drug is observed from 15 to 30 minutes after taking the pill. The effect of the drug lasts about 3-6 hours.
How suitable is Dramina for children? Instructions for use and reviews on this subject will be discussed below.
The active component is distributed over the tissues of the body, entering into an active relationship with plasma proteins. A high concentration of dimenhydrinate is able to overcome the blood-placental and blood-brain barriers. Decay products are excreted in about a day via the kidneys.
The ability to eliminate nausea and vomiting is due to blocking the production of acetylcholine, as well as reducing its secretion into the synaptic cleft at the level of presynaptic endings. The drug has a depressing effect on the vestibular apparatus. "Dramina" acts on the semicircular canals of the inner ear, which are responsible for balance.
Indications
In accordance with the instructions, "Dramina" has a positive effect on the vestibular apparatus, tablets eliminate nausea and vomiting, dizziness and other symptoms of kinetosis disorders and other origin.
Adult patients are advised to take medication not only during trips, but also in order to prevent the negative consequences of surgery. On the background of taking the drug, the following effects are observed:
- Sedative.
- Antiemetic.
- Anorexigenic.
- Minor antihistamine.
- Soothing and analgesic.
In addition, the drug is able to have an insignificant local anesthetic effect, for example, to relieve a headache that arose against a background of impaired function of the vestibular apparatus.
Contraindications
What else does the instruction tell us? Dramina is practically not used for children. Its use requires caution. Prolonged use of tablets leads to the development of addiction to the active component. For this reason, the effectiveness of the drug is significantly reduced. At the same time, the antihistamine effect is preserved, therefore, it is not recommended to use the “Dramina” tablets as instructions.
The medication is prohibited for use in the first trimester of pregnancy. It is possible to prescribe the drug in subsequent trimesters, but only if absolutely necessary, when the potential risk for the woman and the fetus is lower than the expected therapeutic effect. According to studies, dimenhydrinate can cause cardiovascular problems, as well as inguinal hernia in the fetus. During lactation, the drug is also prohibited, since the active component has the property of passing into breast milk in small amounts.
According to the instructions, "Dramin" can not be assigned under the following conditions:
- Epilepsy.
- Dermatoses of any origin.
- Cramps.
With caution, the drug is prescribed for patients with bronchial asthma, obstruction of the bladder neck, peptic ulcer, hyperthyroidism, angle-closure glaucoma, etc.
Instructions for tablets from motion sickness "Dramina"
The dosage regimen and duration of use of the drug should be adjusted by the attending physician. The prescribed dosages should not exceed the maximum daily dosages of the drug specified in the instructions. The drug is taken before meals.
For adults, the daily dosage cannot be more than 400 mg. It is divided into several doses of 50-100 mg. For prophylactic purposes with kinetosis, the drug is taken once 30 minutes before the trip.
As confirmed in the instructions and reviews, "Dramina" also helps children well.
Patients over 12 years of age are prescribed the same dosage as adults. For children aged seven to 12 years, the daily dosage is halved. In this case, the multiplicity of receptions remains the same. The daily dosage for children under 12 years of age should not be more than 150 mg. At the age of less than seven years, but older than a year, a quarter of the daily dosage is given. The question of a second course of admission should be decided by the attending physician.
If you need to take "Dramina" during lactation, then breastfeeding for the treatment period should be canceled. It will be possible to resume lactation a week after the end of treatment, when the active component of the drug is completely excreted.
Adverse reactions
In accordance with the instructions for "Dramina" 50 mg, the central nervous system is mainly affected by the negative effect of the drug. In this case, the following symptoms are observed:
- Fatigue and weakness.
- Violation of psychomotor reactions.
- Headache.
- Violation of wakefulness and sleep.
- Anxiety and a sense of anxiety.
In rare cases, there may be a deterioration in color and night vision, blurred vision and impaired accommodation.
The digestive system can respond to Dramin intake with dry mouth and decreased appetite. In addition, both diarrhea and constipation can develop. In rare cases, nausea and vomiting may occur, as well as soreness in the stomach.
On the part of the breath, a decreased production of bronchial secretion, dry mucous membranes is possible.
The heart and blood vessels can also be affected by the drug. This is manifested by a hemolytic variety of anemia, tachycardia and hypotension.
An allergic reaction to the components of the drug, accompanied by itching, rash, spasm of the bronchi and angioedema, is also possible.
In some cases, difficulty urinating is possible. The development of these symptoms is a reason for refusing to take pills and going to the doctor.
Compatibility with other drugs
The effect of "Dramina" from motion sickness according to the instructions can be enhanced while taking sedatives, as well as drugs that inhibit the nervous system.
In combination with atropine, M-anticholinergics, sedatives, hypnotics, antipsychotics and antidepressants "Dramina" increases their effect.
The drug is incompatible with antibiotics of the ototoxic variety from the category of aminoglycosides. This is due to the fact that "Dramina" veils the ototoxicity of drugs, leading to irreversible hearing impairment and complicating a detailed diagnosis.
The risk of impaired visual function increases while taking the drug with bismuth, painkillers and psychotropic drugs, as well as scopolamines.
"Dramina" is able to reduce the effectiveness of taking anticoagulants and corticosteroids. The drug also reduces the response to apomorphine and the effect of acetylcholine on the heart muscles.
Special recommendations
While taking Dramina, a person should avoid activities that require an increased reaction rate and a high concentration of attention. This is due to the ability of the drug to influence the psychomotor reactions of a person. When taking pills, you cannot drive a car, various mechanisms, etc. The combination of Dramina with alcoholic beverages is also prohibited.
With increased precautions, the drug is taken for epilepsy, impaired urination, diseases of the heart and blood vessels, prostatic hyperplasia and angle-closure glaucoma.
Overdose
Taking excessive amounts of Dramina tablets may lead to an overdose. It manifests itself with the following symptoms:
- Dry mucous membranes of the oral cavity and respiratory tract.
- Labored breathing.
- Confusion, fainting.
- Convulsive syndrome.
- Hallucinations, especially in childhood.
Treatment of an overdose consists in washing the stomach with the subsequent intake of enterosorbents. In addition, symptomatic treatment is carried out, including taking salt laxatives.
Analogs
The following drugs can become substitutes for Dramina:
- "Aviamarin." It is a complete analogue of the drug. Indications are identical to "Dramina". Children are prescribed starting from the age of three. It is forbidden for admission in the first trimester of pregnancy, as well as during breastfeeding.
- Ciel Teva. The basic substance is the same as in Dramin. However, it can be taken both by pregnant and lactating women.
- "Cinnarizine." The main component is different, but the readings are similar to Dramina. Prohibited for admission under the age of 12 years.
- Omaron This is a combination drug, which includes piracetam and cinnarizine. Indications are identical with Dramina. Children can be prescribed the drug from the age of five. "Omaron" is contraindicated in pregnant and lactating women.