Everyone has a runny nose, and the causes of such a problem can be quite different. Therefore, in pharmacies you can see a large selection of drugs that help to cope with this unpleasant condition. One such remedy is called Nazarel. Instructions for use, reviews, analogues of this drug will be considered in the article.
Oh, this runny nose!
As stated in a children's book about a fantastic future, runny nose will remain the only problem that humanity will not be able to solve by the middle of the 21st century. Well, a runny nose remains a serious problem that complicates the life of the one who caught it. Rhinitis develops, and it is this official name that this problem has, maybe for several reasons:
- body reaction to allergens - pollen, gas contamination, certain foods and substances;
- the result of the inflammatory process against a background of a viral or bacterial infection;
- a side effect of some diseases - measles, flu, some others.
Rhinitis, like the vast majority of other diseases, can occur in both acute and chronic form. One of the drugs used to treat various forms of the common cold is Nazarel (spray). The instruction to it tells in sufficient detail about the tool itself and the conditions for its use.
What dosage forms can I buy "Nazarel"?
Medicines for the common cold of various origins are one of the most popular groups of medicines in pharmacies. Rhinitis interferes with the usual life, because lack of breathing, flow from the nose, feeling of stuffiness has a negative effect on self-awareness. The drug "Nazarel", the instructions for which are enclosed in each package of the drug, helps to cope with the main symptoms of the common cold. In what pharmaceutical forms is this drug produced? There are no Nazarel drops, the instructions confirm this. A pharmaceutical product under this name is produced by Czech companies IVAX Pharmaceuticals sro and Teva Czech Industries sro in a single form - in the form of a nasal spray. The bottle is made of dark glass and is equipped with a spray tip of a convenient elongated shape and a protective cap. Each bottle is packaged in an individual cardboard box, which contains instructions for use.
What works in the drug?
Contains all the detailed information about the drug "Nazarel" (nasal spray) instructions. She points out that only one component works in it - fluticasone propionate. In one dose of the drug, this substance will be exactly 50 ml. As auxiliary components, the composition of the medicine includes:
- dextrose;
- polysorbate;
- benzalkonium chloride;
- phenylethanol;
- dispersive cellulose;
To give the drug the desired concentration, water is used. The sprayed substance is homogeneous, that is, homogeneous, opaque, has a white color. Vials of the drug in pharmacies can be purchased in the amount of 60, 120 or 150 doses.
How does the active component work?
For the drug "Nazarel", the instructions for use clearly specify the pharmaceutical accessory - glucocorticosteroid for topical use.
The substance of fluticasone propionate in this medicine has a local effect, manifesting its anti-inflammatory, anti-allergic and decongestant properties.
This functionality of the active component is due to its ability to interact with glucocorticosteroid receptors in the human body - it inhibits the ability of reproduction by dividing mast cells, lymphocytes, macrophages, eosinophils, neutrophils. Also, this substance affects histamine, leukotrienes, prostaglandins, cytokines and other inflammatory mediators by reducing their production. Fluticasone propionate is active during the initial and late phases of an allergic reaction. Its local application has a therapeutic effect 2-4 hours after a single spray, and the action lasts a day. Using "Nazarel" allows you to get rid of such unpleasant sensations of rhinitis as runny nose and sneezing, itching in the nose and nasal congestion. The action of the drug also actively reduces the feeling of pressure in the paranasal sinuses, as well as eye reactions against allergic rhinitis.
What is the pharmaceutical route?
Talks about the drug "Nazarel" (spray) instructions for use. It indicates that the drug, when used in therapeutic doses, does not have a systemic effect on the body. This is due to topical application of the drug and the inability of the active substance fluticasone propionate to dissolve in water. The intranasal use of the drug in the dosages indicated by the doctor even makes it possible to detect it in the blood plasma in any significant parameters. Since the medicine is poorly absorbed, and the nasopharynx is arranged so that the excess fluid that accumulates on the nasal mucosa can be swallowed, a certain amount of the medicine is swallowed. But even in the stomach it is not absorbed for the same reasons, the concentration of the active substance in the blood plasma practically does not increase.
Fluticasone propionate has the ability to pass through the liver twice: the first passage leads to the metabolism of most of the substance with the formation of an inactive metabolite of the carboxyl group. The second passage leads to the withdrawal of the drug from the body through the intestines, and the renal clearance of both the active component and its metabolite is less than 5%.
In what cases is a medicine prescribed for use?
One of the sought-after medicines that help solve the problem of rhinitis of various etiologies is the Nazarel spray. The instruction for use of this tool tells in which cases its use is indicated - for the treatment of rhinitis of allergic origin, both seasonal and year-round. Also, this drug can be used for prophylactic purposes to prevent the development of a runny nose against an allergy background.
Are there any contraindications?
For the intranasal preparation "Nazarel" (spray), the instructions for use indicate that it is not recommended for children under 4 years of age for treatment and prevention. For other groups of people in need of this drug, a contraindication will be only hypersensitivity to the active component, fluticasone propionate, and to other components of the drug. Only a specialist can solve the question of the appointment for use of this particular intranasal drug, taking into account the diagnosis made, as well as the patient’s history.
Special periods in a woman’s life
The preparation "Nazarel" is worthwhile to use the drug "Nazarel" in the treatment of rhinitis for pregnant and breast-feeding women, the instructions for use. The active substance of this medicine, fluticasone propionate, is poorly absorbed into the active bloodstream, which means it does not have any significant systemic effect on the human body. But, despite this proven fact, the use of "Nazarel" during pregnancy is not recommended. Its use can only be recommended by a doctor if the benefits to the mother's well-being significantly exceed the risk to the fetus. Studies on the penetration of fluticasone propionate into breast milk have not been conducted, and therefore a medicine based on it is not recommended in therapy for women breast-feeding a baby.
Potential negative
Use in the treatment of allergic rhinitis can be the drug "Nazarel". The instructions to it indicate that only a doctor can prescribe treatment or prevention of a runny nose with this medicine. As with any other remedy, Nazarel spray has the potential for side effects. Moreover, according to the World Health Organization, some of the negative effects occur in patients when using this medication quite often. These are headaches, violation of smell and taste, irritation and dryness of the mucous membranes of the nose and nasopharynx, nosebleeds. In rare and very rare cases, anaphylactic shock, bronchospasm, skin rash, increased intraocular pressure, the development of cataracts and glaucoma, osteoporosis, growth retardation in children are noted.
In the event of any unpleasant consequences of the use of this drug in the treatment of rhinitis, it is necessary to notify the attending physician about this, cancel the drug and, with the help of a specialist, choose another medicine.
How to use the medicine?
Intranasal dosage spray "Nazarel" is used for children. The instructions for the medicine stipulate the age of the child - from 4 years. How to use this drug taking into account the age of a person in need of his help?
For children from 4 to 12 years of age, the medicine should be used only 1 time per day: one press in each nostril (one dose) allows the child to get rid of rhinitis for 24 hours. Children over 12 years old and adults, including the elderly, also use the drug once a day, but to get the desired effect they need to make two clicks in each nostril.
The medicine is best used in the morning. If necessary, the use of the spray is carried out twice a day. When the desired effect of using "Nazarel" is achieved, the application can be reduced to a single press of one button in each nostril.
How to use a spray bottle correctly? At the first use of the medicine after purchase, as well as after a break in use for more than a week, it is necessary to remove the protective cap and make 6 clicks to clean the sprayer. The medicine itself is administered according to the following algorithm:
- clean out the nasal passages - blow your nose, use a napkin or cotton flagellum;
- remove the protective cap from the sprayer, after shaking the bottle;
- insert the tip into one nostril, hold the second with your finger;
- tilt your head forward slightly, while holding the bottle vertically;
- make one click, while breathing in air;
- hold your breath by removing the bottle;
- exhale by mouth.
Repeat the entire algorithm with a second nasal passage. Then carefully wipe the spray tip with a napkin and close it tightly with a cap. If you use the Nazarel spray for children, the instructions for administering the medicine will be exactly the same as for adults.
Can I use the medicine in complex therapy?
For many patients who have several diseases at the moment, the question of the interaction of the drugs used is important. For the Nazarel medicinal spray, the instructions for use stipulate that the active component does not have any significant central effect, since it practically does not penetrate into the systemic circulation. That is why we can say that this drug has no interaction with other medicinal substances. But since scientific research in this area has not been carried out, it is necessary to get advice from the attending physician on the use of all necessary drugs in combination.
How to buy and how to store medicine?
All the necessary information contains about the preparation "Nazarel" instruction. Its analogs, as well as the medicine itself, are sold in pharmacies according to the prescription of a specialist. After opening the bottle and the necessary course of treatment, the drug remains suitable for the entire period indicated by the manufacturer on the package. It is 3 years, after which it is impossible to use the remedy for treatment!
The medicine is sold at a very affordable price, which averages about 400 rubles per bottle, containing 120 doses of the active ingredient.
Some features of the drug
A frequently prescribed medicine to help patients with allergic rhinitis is the Nazarel drug. The instructions for the use of this tool indicate that it can only be used as prescribed by a doctor, and children under 4 years old, as well as pregnant and lactating women can not use it. After each use, the cap with the spray gun must be wiped with a napkin, and the bottle should be carefully closed, in a place protected from sunlight.
Are there any analogues?
All detailed information about Nazarel Intranasal Spray contains instructions for use. Its analogues should have the same therapeutic effect as the active substance fluticasone propionate. Such drugs are widely represented in the line of pharmacy products against the common cold. These are Beclomethasone, Benarin, Nasobek, Polydex. For example, in the drug Benarin, budesonide, also related to glucocorticoids, acts as an active component, and in the drug Nasobek, beclamethasone is functional. There are also synonyms for the drug Nazarel ". Fluticasone propionate works in them - these are the drugs under the names" Flixonase "," Avamix "," Nazofan ". Also, in pharmacies you can buy the generic" Fluticasone ". Which drug should be preferred in this or that case, only the attending physician will decide given many about circumstances relating to a particular patient.
What do patients say about the drug?
For the drug "Nazarel" instructions, patient reviews are a set of recommendatory information. Indeed, the vast majority of those who have used or are using this spray in the treatment of the common cold caused by allergies speak of it with gratitude only. People note a very convenient mode of use - once a day, it is almost impossible to disrupt or skip the use of the drug. A rare manifestation of the side effect of the active component is also noted. Many of those who need constant use of anti-rhinitis drugs note that the drug can be bought in different dosages, so a 150-dose bottle lasts for two and a half months of regular use.
The opinion of experts
Before using or prescribing a medicine, each patient and specialist needs to familiarize themselves with detailed information about him. Talks about the spray "Nazarel" instructions for use. Reviews of experts about him are quite positive. Based on the experience of the appointment in the treatment of allergic rhinitis, doctors note the effectiveness of the drug. According to patients, the drug rarely causes unnecessary effects. At the same time, its effectiveness allows you to use it in a gentle mode - only once in 24 hours. Also, experts note the fact that the medicine can be used in complex therapy, since it does not have a systemic effect on the patient's body.
The drug in the form of a Nazarel nasal spray, the instructions for which are enclosed in each package, is one of the most popular therapeutic agents for the treatment of allergic rhinitis. Fluticasone propionate is not absorbed into the systemic circulation, exerting a local effect, removing the manifestations of the common cold, which helps patients feel much better.