In the article, we consider the instructions for use for the Ersefuril remedy.
Most people know what diarrhea is. This pathology can be triggered by various reasons: the reasons can be commonplace, for example, poor-quality products, alcoholic drinks and the like, but sometimes more dangerous, such as intestinal infections. On sale there are many medications that will assist in the treatment of this disease state. Ercefuril is considered the best antiseptic, although often patients mistakenly consider it an antibiotic. Its second name, international - "Nifuroxazide" (for the active ingredient in the composition).
Pharmacological forms of this drug
What can be learned from the instructions for Ercefuril? The drug is made exclusively in capsule form. The drug does not have other pharmacological forms. Use capsules orally. The drug is packaged in blister packs, each of which contains 14 capsules. In a cardboard bundle, 1 or 2 cell blisters can be located.
Instructions for use with Ersefuril for children will be discussed below.
Composition, description
The capsules of the preparation are gelatinous, have a yellow color, are hard, have a size of No. 1. Each of them contains a powder.
The main active component of the drug is nifuroxazide. Each capsule contains 200 mg of the main component. In addition to nifuroxazide, the preparation contains such auxiliary ingredients as sucrose, magnesium stearate, and corn starch. The capsule shell is made of titanium dioxide, yellow iron oxide, used as a dye, gelatin.
Pharmacological group
In accordance with the instructions for Ersefuril, the main effect of the medication is antimicrobial. It belongs to the group of intestinal antiseptics, antidiarrheal drugs.
Nifuroxazide is a derivative of nitrofuran. Under the influence of this component, dehydrogenase activity is blocked, respiratory chains, tricarboxylic acid cycles, and other processes in the microbial cell are inhibited. Nifuroxazide also destructively affects the membrane of the microbial cell, reduces the ability of the microorganism to produce toxins. The activity of the main component is observed against Vibrio parahaemolytique, Vibrio cholerae, Clostridium perfringens, Salmonella spp., Campylobacter jejuni.
Proteus indologenes, Enterobacter cloacae, Citrobacter spp. Have weak sensitivity to nifuroxazide. Microorganisms such as Providencia spp., Proteus mirabilis, Pseudomonas spp., Klebsiella spp. Are resistant to Ersefuril.
While using Ersefuril, the balance of intestinal microflora is not disturbed. If nifuroxazide is used to treat diarrhea of bacterial origin, it is able to normalize intestinal eubiosis. When infected with enterotropic viruses, it acts as an obstacle to the emergence of superinfection of a bacterial nature.
In the digestive tract, nifuroxazide is practically not absorbed, the antibacterial effect of the drug is observed exclusively in the intestinal lumen. The drug is removed by the intestine, about 20% of the used dose is evacuated unchanged, the rest - in the form of metabolites.
Indications for use
As indicated by the instruction, Ersefuril is often used to combat disorders involving antibacterial therapy.
For adult patients, the medication is prescribed for diarrhea, which is bacterial in nature, acute in nature, proceeding without obvious signs of a deterioration in the patient’s well-being - intoxication manifestations and fever.
For children, the drug is prescribed in similar cases as for adults. The use of the drug from 3 years is allowed.
Information on the negative effects of the active component on the fetus during pregnancy is not available. Despite this, experts do not recommend the use of the drug in this category of patients. This is due to the lack of a sufficient number of studies confirming the safety of the drug and describing the likely effects on the body of a pregnant woman. If necessary, the drug can be prescribed in the lactation period, however, therapy should be carried out under the supervision of a doctor and short courses.
Contraindications
According to the instructions for Ercefuril, the use of a medication may not be possible if some factors are present. So, it is contraindicated in pregnant women, children under 3 years of age, patients with individual susceptibility to any of the components of the drug.
Since a component such as sucrose is present in the preparation, it should not be used for the treatment of patients suffering from fructose intolerance, isomaltase and sucrose deficiency, glucose-galactose malabsorption syndrome.
This is confirmed by the instructions for Ercefuril capsules.
Use of this drug
On average, therapy takes up to 7 days. It should be noted that in the absence of positive effects within three days from the start of the use of the drug should consult with a specialist.
For adult patients, the drug is shown in the amount of 1 capsule, which must be taken four times a day. Between receptions should be left the same time intervals of about 6 hours.
Consider the instructions for Ercefuril for children.
When treating children, lower dosages are recommended. So, patients 3-6 years old should take one capsule, and the frequency of doses is reduced to 3. Children 6-18 years of age are also assigned one capsule per reception, and the frequency of doses can reach 4 at the discretion of the doctor.
Pregnant women use Ercefuril is contraindicated.
If necessary, the drug can be used by lactating women. The dosage and regimen in this case should be determined by the doctor.
Negative impact
According to the instructions and reviews for Ersefuril, negative reactions such as skin rashes, angioedema, anaphylactic shock, urticaria can develop against the background of using the medication.
If any of these side effects develops, the patient should consult a doctor.
Interaction of Ersefuril with other medicines
You should not take "Ersefuril" in parallel with drugs that can provoke the development of disulfiram-like reactions.
It is not recommended to be combined with medications that depress the central nervous system.
What else does the Ersefuril capsule application guide tell us?
Special instructions for use
Throughout the course of therapy using the medication, the patient is shown to undergo rehydration procedures.
In the event of additional negative clinical symptoms, expressed in worsening condition, high temperature, symptoms of intoxication, it is necessary to consult a treating specialist who is likely to make adjustments to the treatment regimen or advise the use of systemic antibacterial medicines.
Alcohol is not allowed throughout the course of therapy.
The composition of the drug includes sucrose. You should pay attention to this if it is intended to conduct therapy for patients with diagnosed diabetes mellitus.
Ersefuril is not able to affect the ability of patients to perform work associated with the management of complex mechanisms and vehicles and requiring increased concentration, speed of psychomotor reactions.
Overdose
There are currently no reported cases of overdose with Ersefuril. However, it should be borne in mind that the use of the drug in excessively high doses can provoke the development of pronounced negative reactions. In such cases, symptomatic therapy should be prescribed to the patient.
Storage
Ersefuril must be stored in a place that is protected from sunlight, moisture, inaccessible to children. Storage temperature should be room temperature.
The drug retains its medicinal properties, subject to proper storage, for 5 years. It is unacceptable to use the medication after its expiration date has expired.
In drugstores, he is released freely, that is, a prescription is not required for his purchase.
We will not consider in detail the instructions for the analogues of Ersefuril.
Analogs
Currently, there are many drugs, the composition and effect of which is similar to Ersefuril. The most popular are:
- "Nifuroxazide." Able to have antibacterial effects. The manufacturer produces two pharmacological forms - in the form of a suspension and tablets. The use of the drug in the treatment of children from 2 months is allowed. The mechanism of action of the drug is completely similar to that of Ersefuril.
- "Mirofuril." This medication is produced by the manufacturer in capsule form, as well as in the form of a suspension. The active substance in its composition is similar to that in Ersefuril. Indications for use are similar. Mirofuril has an antimicrobial effect. It can be used in the treatment of children from 1 month.
- Enterofuril. It is an antimicrobial medication with a wide range of effects. It can be in two pharmacological forms - capsules and suspensions. It is recommended for use not only with diarrhea, but also with gastrointestinal lesions having a bacterial etymology, chronic in nature, accompanied by dyspeptic manifestations.
If it is necessary to replace Ercefuril with a similar medication, consult a specialist who will assess the feasibility of choosing another drug.
Cost
Currently, the average cost of one package of Ersefuril, which includes 14 capsules, is 320 rubles. It depends on the region and the pharmacy network.
Reviews for Ercefuril
The reviews left by patients are almost all positive. Consumers note the high effectiveness of the drug as an intestinal antiseptic, speed of action, almost complete safety.
The only often noted drawback of the drug is its unreasonably high cost. There are many similar products with a similar composition and mechanism of action, the price of which is much lower.
It is important to remember that the need to use the medication, as well as the treatment regimen with his help, should be determined by a specialist.
We reviewed the Ersefuril product instructions for use and reviews.