Today, heart pathologies are often diagnosed in people of different ages and gender. Heart failure develops for many reasons. In medicine, there are many drugs whose action is aimed at eliminating negative symptoms, reducing the risk of complications. One such drug is Presartan. The instructions for the medication indicate that it belongs to the group of cardiovascular drugs that regulate blood pressure and affect the renin-angiotensin system.
Characterization and description of the drug
"Presartan" - pills for white pressure and oval shape. One tablet may contain 25 or 50 milligrams of the active substance - losartan. As additional components, corn starch, talc and cellulose, magnesium stearate, silicon dioxide and others are used.
Three blisters of ten pills in each or two blisters of fourteen tablets each can fit in one package.
Store the medicine in a dark place where the air temperature does not exceed twenty-five degrees. Shelf life is three years.
With this drug, antihypertensive therapy is carried out in case of chronic heart failure, hypertension, chronic ischemia, as well as in the case when treatment with ATP inhibitors did not give the desired result. Often, a medication is prescribed as a prophylaxis of pathologies of the cardiovascular system with hypertrophy of the left ventricle of the heart.
The use of a medicine to protect the liver in those people who suffer from type 2 diabetes is also indicated if it is accompanied by high blood pressure in order to reduce the intensity of organ damage.
Drug action
The effect of the drug is determined by its composition. "Presartan" contains losartan, which acts as an antagonist of receptors of the angiotensin of the second type. It helps to reduce resistance in peripheral vessels, reduces the load on the heart, and lowers blood pressure.
Many will also be interested in why losartan still helps. This component eliminates the symptoms of pulmonary hypertension, increases the body's stamina when performing power loads, removes excess fluid from the body along with sodium ions.
The active substance of the drug "Presartan" after it enters the stomach is well absorbed in it, it breaks down into metabolites in the liver. Its bioavailability is 33%. After two hours, the half-life of losartan, along with urine and bile, begins.
"Presartan": instructions for use
For hypertension, it is recommended that you first use the drug in a daily dosage of 25 milligrams, take one tablet per day. Gradually, the dosage is increased to 50 milligrams per day, a tablet is drunk once a day.
After six weeks of antihypertensive therapy, the maximum effect can be expected. If necessary, the dosage of the drug can be increased by the attending doctor to 100 milligrams per day. Then the tablets are taken twice a day.
In heart failure, the drug is taken once a day at a dosage of 12.5 milligrams (half a tablet). After a week, the dosage is increased to 25 milligrams per day, and after another seven days - up to 50 milligrams per day. It all depends on how well the patient will tolerate the drug.
With the simultaneous use of diuretics, the daily dosage of the drug should be 25 milligrams. For those who suffer from liver pathologies, the dosage of the drug is prescribed as a minimum.
According to the instructions, “Presartan” is drunk regardless of the meal, but always at the same time. The pill is washed down with a small amount of clean still water. The simultaneous use of other drugs against high blood pressure is allowed.
In those people who suffer from dehydration, symptomatic arterial hypotension may be observed at the initial stage of therapy, in which case they will correct the water-salt balance or reduce the dosage of the drug.
Usage restrictions
There are some contraindications to the use of this tool. These include:
- High susceptibility to the components of the drug.
- Age to eighteen.
- Pregnancy.
- Severe dehydration.
- Hyperkalemia
With caution, the drug is prescribed to those who have liver pathologies, dehydration and cerebrovascular diseases. During breastfeeding, the drug can be used in the event that it will be temporarily discontinued, and the child is transferred to artificial nutrition.
Negative reactions
According to the instructions, “Presartan” can cause side effects. These include:
- muscle and head pain;
- diarrhea;
- swelling
- hyperkalemia
- sleep disorder;
- respiratory distress;
- tachycardia;
- allergic reactions;
- an increase in the concentration of bilirubin in the blood;
- asthenia;
- dizziness;
- runny nose;
- fainting
- pain in the abdomen;
- pharyngitis;
- depression.
Important! A sharp decrease in blood pressure in the presence of pathologies of the vessels of the brain can lead to the development of myocardial infarction or stroke.
But usually the drug is well tolerated by patients, negative reactions occur in rare cases.
The simultaneous use of the drug with potassium preparations leads to the development of hyperkalemia. When using the drug together with other drugs against high blood pressure, their effect is enhanced.
The effect of losartan will be reduced with the simultaneous use of NSAIDs. When using diuretics during treatment with this medication, a drop in blood pressure is possible.
Excess doses
With an overdose of the drug, the following symptoms develop:
- drop in blood pressure;
- bradycardia or, conversely, tachycardia;
- loss of consciousness;
- collapse.
In this case, the treatment is symptomatic. Hemodialysis is not used.
Cost and acquisition of medication
Presartan can be bought at any government pharmacy. But for its acquisition, you need a prescription from a doctor. The cost of the drug is about one hundred and twenty rubles.
Analogs
Today, there are a large number of antihypertensive drugs on the pharmacological market. Therefore, it has Presartan analogues. The most commonly prescribed are:
- Blocktran has a similar composition and pharmacological effect. Its cost is two hundred and eighty rubles per pack of thirty tablets.
- "Vazotens". The composition of the drug includes losartan potassium and hydrochlorothiazide. Together, these components lower blood pressure more effectively than individually. Its cost is two hundred seventy-five rubles.
- "Losartan." The cost of this medicine starts from sixty rubles, which is much less than other analogues of the drug.
- “Lorista” in tablets has the same composition and drug effect. The price of the medicine is six hundred rubles per pack of ninety tablets.
- Centor also has losartan. Its price is about two hundred rubles.
Drugs to lower blood pressure should be prescribed only by a doctor, self-medication can lead to disastrous consequences.
Reviews
There are various reviews about Presartan. Basically, patients respond well to it, indicating the effectiveness of the drug and its relatively low cost. But some note the development of adverse reactions, for example, swelling of the limbs, attacks of tachycardia. Many doctors indicate that the development of side effects is permissible, therefore, does not require discontinuation of the drug. Other doctors prescribe analogues to patients in case of development of unpleasant symptoms.
Often the drug is taken by people of advanced age, while it is very well tolerated by them, it has a low cost. Some patients prefer to use a similar drug called “Losartan.” This is due to the fact that it costs much cheaper, and its composition and pharmacological action are identical to Presartan. In any case, only a qualified specialist can select the necessary drug.
Conclusion
According to the instructions, "Presartan" is the medicine that lowers blood pressure. Today, this medication has a large number of analogues, however, it is popular among people who have problems with the cardiovascular system. The drug is dispensed in pharmacies by prescription, it has a small list of contraindications and adverse reactions. It is generally well tolerated by patients, including those of advanced age.
The drug is intended for prolonged use. The maximum effect can be felt already in the sixth week of its application. The dosage of the drug is selected by the doctor in each case, as necessary, it can be adjusted during therapy.
If all the prescriptions and recommendations of the doctor are observed, patients will not have health problems during treatment with antihypertensive drugs. In addition, the medicine will help reduce the risks of developing strokes and heart attacks.