Many medicines, when taken together with alcohol-containing drinks, form quite dangerous compounds, as a result of which severe consequences for the individual's body occur. In this article, we will consider how the combined use of alcohol and Suprax, an antibacterial agent (in the dosage form it is dispersible tablets), affects the patient's condition.
Description of the drug. Pharmachologic effect. Pharmacokinetics
The active substance of the drug "Supraks Solutab" is cefixime trihydrate. Of the additional substances it contains:
- magnesium stearate;
- microcrystalline cellulose;
- hyprolosis;
- colloidal silicon dioxide;
- povidone;
- calcium saccharinate;
- calcium carmellose.
As well as flavorings and colorings.
The drug belongs to the group of semi-synthetic cephalosporin antibacterial agents belonging to the third generation. According to the instructions for use, Suprax in tablets has a bactericidal effect, inhibits the production of cell membranes. The drug is quite resistant to beta-lactamases, which are synthesized by bacteria, both gram-positive and gram-negative. Four hours after taking the drug, its maximum concentration in blood serum is achieved. The elimination half-life is within three to four hours and depends on the dose. Unchanged, approximately fifty percent is excreted by the kidneys and about ten percent with bile. The elimination half-life increases with an existing kidney pathology.
Indications for the use of Suprax Solutab
What does Supraks Solutab help from? Doctors recommend this medicine for inflammatory diseases of an infectious nature, provoked by bacteria that are sensitive to Suprax:
- acute and chronic bronchitis;
- otitis media;
- uncomplicated gonorrhea;
- shigellosis;
- sinusitis;
- pharyngitis;
- tonsillitis;
- uncomplicated infectious processes in the urinary tract.
Contraindications
Among the contraindications, individual sensitivity to the antibacterial drugs of the penicillin and cephalosporin series and the components of the drug should be noted, and it is also not indicated for use in children with low body weight (up to 25 kg) and for children with impaired renal function.
With caution, its use is indicated for renal failure in the chronic phase, in the elderly and for inflammation of the large intestine, which was provoked by the use of antibiotics. Using the drug while the baby is waiting is possible if the potential risk to the fetus is lower than the benefit to the expectant mother. During the administration of the product, natural feeding is stopped.
Side effects
Among the undesirable reactions can be distinguished such as:
- Itching and redness of the dermis, exudative erythema, fever, anaphylactic shock.
- Nausea, flatulence, pain in the abdomen, dysbiosis, stomatitis, jaundice.
- Cramps, dizziness, tinnitus.
- Thrombocytopenia, anemia, agranulocytosis, leukopenia.
- Genital itching, vaginitis.
- Shortness of breath, candidiasis.
- Acute renal failure, impaired renal function.
In addition, there are other adverse effects associated with taking Suprax Solutab tablets.
Suprax and Alcohol: Compatibility
There are known reasons explaining why it is impossible to drink alcohol-containing liquids and antibiotics at the same time, including Supraks. For example, the metabolites that are formed during the absorption of antibacterial substances significantly complicate the entire process of alcohol decomposition. As a result, an overestimated amount of acetic aldehyde appears in the body of the individual, which provokes the development of the following undesirable effects:
- vomiting
- cramps
- headache;
- nausea;
- difficulty breathing
- a feeling of heat in the chest, neck and face;
- tachycardia.
In the case of taking large doses of both alcohol and the antibiotic of the cephalosporin group, to which Suprax Solutab belongs, there is a high probability of death. In this case, the form of release of the medication does not matter. The above signs appear in any case. In addition, the liver suffers from the joint intake of alcohol and Supraks Solutab. Having received a large load, it is difficult to cope with the splitting of the drug. As a result, the antibiotic is practically not absorbed and side effects appear. The drug, which is in the body of an individual, blocks the breakdown of ethanol, causing poisoning, which will intensify and accumulate. Thus, we can conclude that Suprax is absolutely incompatible with alcohol-containing drinks.
What to do with the negative consequences caused by taking Suprax and ethanol?
In case of intoxication caused by the simultaneous use of alcohol and Suprax, the following recommendations should be used:
- stop taking alcohol-containing fluids;
- drink more water;
- see a doctor if necessary.
It is important to remember that even a single dose of alcohol, taken in conjunction with drugs, has an adverse effect on the body of the individual. As a result, antibiotic treatment will not bring a positive effect, but will only aggravate the patient's condition. People who encounter such a problem in their reviews recommend:
- Do not mix alcohol with Suprax Solutab.
- Finish the course of treatment, take a short break, so that the body grows stronger, and only after that take the minimum amount of alcohol, since the reaction to the joint administration of a medication and an alcohol-containing drink can be completely unpredictable.
How much after "Suprax" can I take alcohol?
In order to correctly answer this question, one must have information about the compatibility of the drug and alcohol, and also know the period of removal of the drug from the body of the individual, since the greater the danger for the individual's body is the combination of alcohol-containing drinks with an antibiotic, the longer the interval between the end of drug withdrawal and drinking time.
Regarding the Suprax, the following can be said. Due to the fact that the structure of the molecule of this agent is somewhat similar to disulfiram, a disulfiram-like reaction forms when Suprax interacts with alcohol. This substance is used to get rid of addiction, it causes an aversion to alcohol. It does not have a negative effect on the body, but when mixed with alcohol-containing liquids it provokes a number of undesirable effects. Thus, the minimum period that must pass is at least one day. However, if the patient has pathologies of the urinary system, then this time increases.
Conclusion
Alcohol, entering the body of an individual, negatively affects all organs and systems. In the stomach, in response to the irritating effect of ethanol, the synthesis of digestive juice increases, in which hydrochloric acid predominates, and the amount of enzyme substances is significantly reduced. Liver cells are destroyed, the brain and central nervous system are affected.
And the simultaneous use of alcohol-containing drinks with antibiotics may well provoke irreversible processes. You should not risk your health and it is best to abandon the combined use of alcohol and Suprax for the treatment period, since the clinical picture of this combination, which manifests itself in the individual, is identical to alcohol intoxication.