In the article, we consider the instructions for "Xylen" in drops and spray.
This drug is an alpha-adrenergic agonist. This is a vasoconstrictor drug that is widely used in the practice of ENT doctors. The use of the drug helps to narrow the blood vessels of the circulatory system in the nasal mucosa. "Xylen" has the following effect - restores the free passage of the nasal passages, prevents hyperemia, that is, the accumulation of blood in the vessels, and also removes swelling from the mucous membrane and facilitates breathing.
The drug begins to act immediately after instillation. Its duration is up to ten hours.
Composition and properties
According to the instructions, "Xylene" is produced both in the form of drops and in the form of a spray. The composition of the drops and spray is practically identical. The dosage of the drug is 0.05% and 0.1% of the active component, which is xylometazoline hydrochloride.
“Xylen” for children according to the instructions is a 0.05% preparation, which contains 0.0005 grams per 1 ml.
In addition, the composition of the drops and spray is supplemented with the following auxiliary components:
- Disodium edetate.
- Dihydrogen phosphate sodium dihydrate.
- Sodium hydrogen phosphate dihydrate.
- Sodium chloride.
- Benzalkonium chloride.
- Purified water.
Drops are available in bottles of 10 and 15 ml.
Xylometazoline hydrochloride is an active component of the drug and is a non-selective alpha-adrenergic agonist. In minimal dosages, the substance acts on alpha1-adrenergic receptors, and in increased doses - on alpha2-adrenergic receptors. When instilled into the nasal passage, the substance has a narrowing effect on the vessels, relieves inflammation and eliminates exudation. The drug effectively removes swelling and redness, and also facilitates respiratory function in the treatment of rhinitis.
Under the condition of nasal use, xylometazoline is practically not absorbed into the systemic circulation, which makes it well tolerated even by young children, as well as patients with hypersensitivity to the nasal mucosa.
Indications for use
As indicated by the instruction, "Xylen" is actively used in modern medical practice in the treatment of various diseases of ENT organs. It is permissible to assign it to both adults and children.
The most common indications for prescribing a medication are:
- The acute form of rhinitis.
- Pollinosis.
- Ethmoiditis.
- Sinusitis
- Otitis media.
- Sphenoiditis.
- Rhinitis provoked by an allergic reaction.
Treatment of otitis media with Xylen involves instillation of the nasal passages, not the ears. Many people believe that the drug can be used to treat eye diseases, but the instruction does not confirm this information.
Excessive nasal discharge is also an indication for the use of Xylen, as well as nasal congestion arising from various viral and respiratory pathologies. Drops are also used after an operation related to the treatment of pathologies of the nose, and also as a prophylaxis before some medical procedures like rhinoscopy.
Contraindications
In accordance with the instructions to "Xylen", absolute contraindications for its use are:
- The presence in the patient's history of surgical operations performed on the meninges.
- The child's age is up to two years when using 0.05% of the drug, as well as the use of 0.1% drops under the age of six years.
- The lactation period.
- Rhinitis of atrophic type.
- Arterial hypertension of a pronounced nature.
- Tachycardia.
- Severe atherosclerosis.
- Hypersensitivity to the components of the drug, including auxiliary.
The instruction to "Xylen" in the nose reports that the following are considered relative contraindications:
- Benign prostatic hyperplasia.
- Diabetes.
- Coronary heart disease.
- Hyperthyroidism
As for the period of gestation, the drug is allowed to be prescribed only after assessing the potential risk to the developing fetus. Special attention is paid to compliance with the prescribed dosages.
Instruction manual
Xylen in spray and drops is intended exclusively for intranasal use. Before distillation of the drug, it is necessary to clear the nasal passages from the mucus.
The interval between two applications should be at least eight hours. The number of days in the course of therapy is determined by the doctor, but it should not exceed a period of five days.
How to apply according to the instructions "Xylen" for children and adults?
The standard dosage regimen is:
- Children who are six years old, and adults - 1-2 instillations of the drug in a dosage of 0.1% up to three times a day.
- Children under six years of age, more than two years of age - 1-2 instillations of the drug in a dosage of 0.05% once or twice a day.
- Children who are under two years of age - 1-2 installations of the drug in a dosage of 0.05% once (with extreme caution).
When skipping instillation, doubling the dosage is not recommended, as this can provoke undesirable reactions.
Adverse reactions
As indicated by the instructions for “Xylen” in spray and drops, if you often use the drug for a long time, the following undesirable reactions may occur:
- Irritation of the nasal mucosa.
- Burning.
- Tingling.
- Sneezing.
- Hypersecretion.
- Dry mucous membrane.
In some cases, the use of the drug can provoke swelling of the mucous membrane, as well as such systemic disorders as cardiac arrhythmias, palpitations, headache, increased pressure in the arteries, vomiting, sleep and vision disorders. Against the background of prolonged use of Xylen in excess of the prescribed dosages, depression of the nervous system may occur, accompanied by a depressive state.
If the above symptoms appear, stop using Xylen and consult a doctor. The specialist will adjust the dosages or pick up another drug.
Overdose
According to the instructions and reviews to "Xylen", with uncontrolled use of the drug in excess of the dosage prescribed by the instructions, the following system changes occur:
- Pain in the neck and temples.
- High blood pressure in the arteries.
- The state of depression.
- Drowsiness and apathy in relation to what is happening.
- Fatigue and lethargy.
- Dizziness.
- Increased intensity of adverse reactions.
Overdose symptoms are eliminated by drug withdrawal. In some cases, symptomatic treatment may also be required.
This is confirmed by the instruction for drops in the nose "Xylen".
Analogs
In pharmacies, you can find quite a few drugs, the basis of which is xylometazoline. Xylene is one of the most affordable, but it has a rather impressive list of limitations and possible adverse reactions.
Some compare the effect of "Xylen" with "Naphthyzine", since both drugs have a vasoconstrictor effect of a pronounced nature. The drugs practically do not differ in price, however, "Naphthyzin" is safe for children up to a year. By their properties, analogues of the drug can also be called:
- "Nesopin."
- "Sanorin."
- "Nazivin."
- "Rinosprey."
- "Nazol."
- "Oxymetazoline."
- Afrin.
Structural analogues of Xylen include the following drugs:
- Rinorus.
- "Galazolin."
- "Rinostop."
- "Asterisk Noz."
Before using a similar drug, you need to consult a specialist, since each drug has its own contraindications.
Reviews
The most attractive “Xylen” drops are their low cost (around 20 rubles per package), as well as a quick and lasting effect after use. Drops are convenient to use, as the bottle is equipped with a special dropper.
Many patients who used the drug noted that drops help cope with congestion, but then breathing problems return. This is due to the fact that Xylen only relieves swelling and inflammation, and also constricts blood vessels, but does not eliminate the cause of congestion, that is, it does not have a therapeutic effect. For this reason, the drug is not suitable for monotherapy and should be prescribed along with other drugs.