The drug "Physiotens" (synonyms: "Moxogamma", "Moxonidine") is included in the category of antihypertensive drugs. They have a central effect. The active substance is moxonidine.
Means "Physiotens" instruction refers to the clinical and pharmacological group of selective antagonists of imidazoline receptors.
A decrease in diastolic and systolic pressure with prolonged and single use is caused by a decrease in the pressor effect of the nervous sympathetic system on peripheral vessels, and a decrease in peripheral resistance. At the same time, the frequency of contractions and cardiac output are not subject to significant changes.
After administration, the drug is absorbed 90% from the digestive system. The drug reaches its maximum concentration in the blood after sixty minutes.
The drug "Physiotens" instruction recommends taking with arterial hypertension.
The use of the drug does not depend on food intake.
The initial dosage of the drug "Physiotens" instruction recommends setting no more than 200 mcg / day.
A single dosage should not be higher than 400 mcg, per day should not be taken more than 600 mcg (divided into two applications).
Hemodialysis patients and those with renal failure are prescribed a minimum therapeutic dosage of 200 mcg. These patients should not take more than 400 mcg per day.
The withdrawal of the drug "Physiotens" is recommended by the instruction, gradually lowering the dose.
When using the medicine, the development of negative manifestations is possible. During treatment, sleep disorders, nausea, drowsiness, dry mouth, headache, angioedema, dizziness may occur. Taking the medication can provoke orthostatic hypotension, an excessive sharp decrease in blood pressure, skin rash, peripheral edema, and asthenia.
As practice shows, these effects are eliminated gradually after the first weeks of therapy. If negative reactions persist or intensify, you should consult a doctor. You may need to cancel the medicine.
The drug is not prescribed for sick sinus syndrome (SSS), severe bradycardia, in patients under the age of eighteen years (due to limited clinical experience), as well as for hypersensitivity.
With caution, the medicine "Physiotens" is prescribed for kidney failure in a chronic course, as well as for severe liver failure.
Due to the poorly understood effect of the Physiotens medication on the condition of the fetus and pregnant woman, the doctor determines the advisability of the appointment during gestation. It has been established that the active ingredient - moxonidine - is excreted in breast milk. In this regard, if necessary, prescribe the drug Physiotens to a lactating woman, the patient should be warned about the cessation of natural feeding.
Despite the fact that there is no data on the negative effect of the drug on the ability to drive vehicles, mechanisms, and other equipment, one should remember about the possible occurrence of dizziness and drowsiness during therapy.
If necessary, stop taking the drug "Physiotens" and simultaneously taking beta-blockers, first cancel the last, and then (after a few days) the medicine "Physiotens".
ECG, heart rate, and blood pressure should be monitored throughout therapy.
It is not recommended to prescribe tricyclic antidepressants simultaneously with the Physiotens medicine.
The medication is allowed for use with thiazide diuretics, as well as ACE inhibitors.
Before you start taking the drug "Physiotens", analogues of the drug (for example, the drug "Moxonitex"), you need to consult a doctor.