In the article, we consider the instructions for use with Riboxin.
The active component that is part of the drug is required by the body to generate energy and the occurrence of biochemical reactions. The drug has a positive effect on the activity of many organs, takes part in the respiration of tissues, and is able to increase heart health. This medication can be used for the purpose of therapy only for adult patients. It is not in the public domain in pharmacy chains; a prescription from a doctor is required for its purchase. The composition of "Riboxin" is of interest to many.
Pharmacological forms
The manufacturer "Riboxin" is available in two pharmacological forms - tablet and injection. Each tablet contains 200 mg of the active component, each ampoule of the injection solution - 20 mg / ml.
Composition, description
According to the instructions for use with Riboxin, the active component in the composition of the drug is inosine, the structure of which contains sugar and a nitrogenous base. In the human body, inosine is a component of transport RNA, delivering amino acids to the site of protein synthesis. Inosine is also a purine base and is involved in the formation of ATP, which is the main energy source for the activity of the body. With a lack of this substance, a violation of many functions occurs, the general condition of the patient worsens.
Inosine is necessary for the normal functioning of many systems and organs, since it:
- Promotes microcirculation of blood in the myocardium, is able to reduce tissue necrotization zones.
- Slows down the destruction of cardiomyocytes.
- Provides energy transport within the cell.
- It takes part in tissue respiration.
- It has a stimulating effect on the production of nucleic acids.
- Affects enzymatic activity in the Krebs cycle.
- Contributes to the activation of metabolism in the myocardium.
- It acts anabolic. That is why Riboxin is so often used in sports.
The pharmacological significance of inosine is a metabolic, antiarrhythmic, antihypoxic effect. Mostly, the drug is used by cardiologists, since against the background of its use, blood circulation in the coronary arteries improves, the supply of myocardium with energy increases, metabolic processes are activated during hypoxia. As a result of the influence of inosine, the force of contraction of the heart muscle increases; during diastole, it fully relaxes. This is the unique composition of Riboxin.
The most important property of the drug is its ability to activate tissue repair, in particular, gastrointestinal mucosa and myocardium.
When the drug is administered intravenously, the entire volume of incoming inosine is attracted by the body to biochemical reactions.
As indicated by the instructions for use, "Riboxin" is a drug that affects the metabolism of the body.
Indications for use
What are the indications of Riboxin? For adult patients, it is prescribed for use in the following cases:
- With the onset of intoxication from cardiac glycosides.
- With myocardial dystrophy.
- In order to correct abnormalities in the heart rhythm.
- After myocardial infarction (in the acute or recovery period).
- As an element of the complex therapy of coronary heart disease.
Also, in addition to cardiology, Riboxin can be used:
- With open-angle glaucoma.
- In order to prevent the development of leukopenia, if radiation therapy is ahead.
- With urocoproporphyria.
- In order to treat liver pathologies.
Contraindications
Instructions for use "Riboxin" contains information about the contraindications of the medication.
Do not use it in the treatment of children, pregnant women. Its use in the lactation period is also prohibited. Such a ban is caused by the lack of sufficient data indicating the safety of the use of Riboxin in these categories of patients.
It is contraindicated to prescribe the drug to patients who have allergic reactions to its components, however, such cases are quite rare.
It is better to refuse to take the medication for patients suffering from hyperuricemia, gout. If the patient has kidney failure, the doctor needs to adjust the dosage of the drug.
Use of medication
When using the “Riboxin” tablet, patients need to swallow the medicine whole without chewing or crushing the tablet. It should be washed down with water in large quantities, and it is better to take them after a meal. The dosage of the medication can vary significantly and should be determined by the doctor individually for each patient. Per day, taking into account the patient’s condition and the nature of the disease, up to 2400 mg can be indicated, which corresponds to a dozen tablets.
The course of "Riboxinum" is recommended to start with a minimum dose of 600 mg, taking the medicine four times a day for 1 tablet. If the drug is well tolerated, then the initial dosage is increased step by step, first twice, and then four times.
The average duration of the course is up to 3 months.
In order to treat urocoproporphyria, it is recommended to take a standard dose of 800 mg, which is divided into four doses.
Riboxin is used intravenously in injections. The introduction can be carried out drip or jet. When using the drip method of administration, it is recommended to administer the drug no faster than 60 cap./min. Before use, the solution should be diluted with sodium chloride or glucose to obtain a volume of 0.25 L. If the response of the body is normal, the dosage is doubled, dividing it into two applications. The average duration of the course of treatment when using injectable "Riboxin" is 15 days.
Inkjet administration of the drug is indicated in the presence of acute cardiac arrhythmias. The recommended dosage in such cases is up to 400 mg.
Negative impact
Against the background of the use of “Riboxin” in injections or tablets, some negative reactions of the body may appear, in connection with which it is important to monitor the patient’s condition at the initial stages of therapy. When using the drug, the following negative symptoms may develop:
- Soreness at the injection site.
- General weakness.
- Hyperuricemia, exacerbation of gout.
- Vomiting
- Headache.
- Nausea.
- Dizziness.
- Reinforced sweat compartment.
- Decrease in blood pressure.
- Heart palpitations.
- Itchy skin.
- Immediate allergic reactions.
- Rash.
With the development of these symptoms, the patient should inform the doctor about them.
Interaction with other medicines
Most often, the interaction of Riboxin with cardiac medications is noted, so with the simultaneous use the therapeutic effect of heparin medicines is enhanced. This is due to the ability of "Riboxin" also affect platelet aggregation.
With parallel use, the inotropic effect of drugs of the cardiac glycoside group is enhanced, thereby reducing the risk of arrhythmia.
When used together with beta-blockers, the effect of "Riboxin" does not change. It is also allowed to combine the medicine with furosemide, nifedipine, spironolactone, nitroglycerin.
Injection "Riboxin" should not be mixed in one container with acids, alkaloids, salts of heavy metals, pyridoxine. Do not use liquids not prescribed for the dilution of the drug.
Special instructions for use
The drug cannot be used as an emergency aid. The development of hyperemia or skin itching should be considered a side effect, which serves as the basis for refusing to use "Riboxin".
During therapy, the patient must periodically monitor the level of urea in blood and urine tests. If the patient has kidney failure, the medication should be limited. For patients of this category, the drug is prescribed only when its use is justified, and the likely benefit exceeds the potential risk.
Lactose is present in the tabletted Riboxin, this is important to consider for patients with rare hereditary intolerances.
The drug does not affect the psychomotor and speed of reactions, therefore, it can be used in patients whose activities are associated with the management of complex mechanisms and vehicles.
Overdose
When an overdose of "Riboxinum" occurs in a patient, the severity of side effects increases, most often allergic ones. Therapy in this case should be canceled, and symptomatic therapy is indicated to the patient.
Analogs of Riboxin
If necessary, Riboxin can be replaced by Inosin-Eskom, Adenocin, Cytoflavin, Remaxol. However, it is important to remember that each of the Riboxin analogues has its own contraindications and negative effects. It is necessary to consider and coordinate the replacement of the medicine with the doctor.
The average cost of packaging a drug in Russian pharmacies is 60 rubles.
Reviews on "Riboxin"
The vast majority of reviews found characterize Riboxin for the better. An important feature of the drug is a short list of negative effects, which seems insignificant in comparison with the indications and the breadth of drug use. Riboxin is indispensable in sports. It acts like an anabolic.
The drug is effective in the treatment of many diseases, including those that affect the heart, gastrointestinal tract, kidneys, and liver.
The availability of the product and its affordable price are separately noted.
However, you must not forget that this drug is a medication, and its appointment should be carried out by a doctor.
Now we know what Riboxin is for.