For what purposes is Laferobion (suppository) prescribed? Instructions and indications for the use of this tool will be presented below. We will also tell you about the composition of the suppositories, whether they have adverse reactions and contraindications, whether the medicine can be used to treat young children, etc.
Composition, packaging of the drug
What determines the high therapeutic efficacy of the Laferobion medication? Candles contain such an active substance as human interferon. Suppositories also include additional components in the form of vitamin E and C, tocopherol acetate and solid fat.
You can buy the drug in a pack of cardboard, inside which contain 3 and 5 candles, placed in plastic packaging.
pharmachologic effect
What is Laferobion? Suppositories have a high antiviral activity and have an immunomodulatory effect. They are used in the treatment of various diseases.
The high therapeutic effectiveness of this medication is due to its unique composition. The active element of suppositories has an antitumor and antiviral effect. Recombinant human interferon has no toxic effects on the body.
After the introduction of a rectal suppository, a number of reactions are launched: proteins are synthesized, proliferation, as well as virus replication, are suppressed, immunity is increased, and so on.
Pharmacokinetics
How long is Laferobion (candles) absorbed? The instruction says that after rectal administration, the maximum concentration of active substances in the blood is observed after 5-10 hours. The half-life of the drug is 2-3 hours.
Indications for use
Why is Laferobion medication prescribed? Candles are used as part of complex therapy of various infections that are caused by:
- human papillomavirus;
- hepatitis B virus (can be used for moderate and severe forms);
- herpes virus (including herpetic lesions of the mucous membranes of the eyes, genital herpes, herpetic eruptions on the skin, herpes zoster, etc.);
- mixed infections, bacterial or viral, including in infants up to one month.
In what other cases do Laferobion suppositories be used? Candles are prescribed as part of the complex therapy of cancer and multiple sclerosis:
- with melanoma of the eyes and skin;
- with tumors of various localization, including cancer of the ovary, bladder, chest and kidneys;
- with Kaposi's sarcoma;
- with myeloma;
- with other malignant tumors.
Contraindications
Are there any contraindications for Laferobion 100000? The instruction attached to the drug states that such a drug is not recommended for use in the following cases:
- with intolerance to the active element (interferon), as well as other components of the drug;
- in the presence of severe liver and kidney diseases;
- in the presence of severe diseases of the heart and blood vessels;
- with inhibition of the myeloid germ of hematopoiesis;
- with diseases of the thyroid gland;
- with epilepsy and other diseases of the central nervous system.
It should also be noted that the suppositories in question are contraindicated for use during gestation and during lactation. Such a ban is due to the lack of necessary clinical studies.
Dosage and application
Laferobion are rectal suppositories that can be prescribed for both adults and young children. As a rule, the course of treatment with such a remedy is about 10 days. This time is enough to activate the human immune system, and the body itself began to fight the infection.
However, it should be noted that the drug in question is prescribed not only as an immunomodulating agent, but also as an antiviral and antitumor drug. Therefore, its dosage should be determined only by the doctor, after a medical examination (depending on the type and severity of the existing disease).
For precancerous diseases of the cervix, papillomavirus infection, mixed, viral and bacterial infections, as well as urogenital mix infections that are sexually transmitted, for adults this drug is prescribed 1 suppository (1.5 million IU) twice a day. Suppositories are recommended to be inserted every 12 hours.
Dosage for children
Is it possible to use Laferobion medication in relation to a child? Suppositories for children are prescribed only as part of complex therapy. The baby is inserted one suppository (150 thousand IU) every 12 hours. The duration of such therapy is 5 days.
In the treatment of meningitis, acute respiratory viral infections, pneumonia of various etiologies, one course is usually enough. As for the treatment of infections caused by the Epstein-Barr virus, in this case, an increase in the duration of the course and dosage is necessary.
Adverse reactions
Few people know, but Laferobion candles (500000-15000000 IU) can cause undesirable consequences. However, the side effects that occur are fairly quick after the end of the course of treatment.
According to the attached instructions, such suppositories can cause the following reactions:
- sleep disturbance (drowsiness, insomnia);
- chills, fever;
- sweating
- fatigue;
- increase in body temperature;
- severe headaches;
- myalgia;
- lethargy;
- arthralgia.
How to get rid of adverse reactions that arose while taking Laferobion medication? Reviews of experts say that in order to reduce these symptoms it is necessary to take the Paracetamol tablet.
It should also be noted that with prolonged therapy with the drug in question, the following side effects may occur in patients:
- dizziness;
- arthralgia;
- drowsiness or irritability;
- paresthesia;
- alopecia;
- ataxia;
- tachycardia;
- cough;
- tides;
- thrombotic and leukocytopenia;
- itching or skin rash ;
- vomiting
- herpetic eruptions.
According to patients' reviews, when using suppositories and other forms of the Laferobion drug, depressive and anxiety states, as well as confusion and nosebleeds, can occur. In this case, you should consult a doctor for advice.
Drug interaction
It is highly recommended not to prescribe suppositories at the same time, as well as other forms of the Laferobion medication with glucocorticosteroids. As for the combined use of this drug with other medicines, there are no contraindications.
Overdose
When using high doses of Laferobion, the patient may develop profound impairment of consciousness, prostration and even lethargy. According to experts, such conditions are reversible and regress immediately after the cessation of the use of the drug.
special instructions
To date, the effect of the drug “Laferobion” on the speed of psychophysical reactions of a person and the ability to control vehicles and complex mechanisms has not been studied. There is also no data on the possible penetration of drugs into breast milk. In this regard, such suppositories are not recommended for women during lactation.
Before using this tool, be sure to read the attached instructions. It states that during treatment with Laferobion it is forbidden to consume any alcoholic beverages.
Candles "Laferobion": reviews of doctors and patients
Like other medications based on interferon, Laferobion suppositories are quite often criticized by many therapists and pediatricians. Experts justify their negative attitude to this medication by the fact that its frequent use can significantly reduce a person’s natural response to the fight against viruses. After all, it is no secret to anyone that with diseases the body itself produces the necessary amount of interferon. However, this applies only to the treatment of acute respiratory viral infections.
As for serious diseases or serious viruses that a person cannot cope on their own, the use of the medication in question is more than justified.
In connection with all of the above, it should be noted that Laferobion suppositories are not recommended for the prevention of diseases, since the body can decide that it no longer needs to produce interferon, which will lead to even greater negative consequences.
As for patients, they note the high effectiveness of this drug, especially in relation to young children. Although some people complain that such a remedy often causes adverse reactions.
Also, patients consider the Laferobion drug to be very expensive. For 10 suppositories (1 million IU) you will have to pay about 700 Russian rubles.