Lordestine tablets, the price of which is from 200 rubles, is a histamine H1 receptor blocker drug. The medication, being the primary active decomposition product of loratadine, inhibits the release of C4 leukotriene and histamine from mast cells, prevents the onset and alleviates the symptoms of an existing allergic reaction. Medication “Lordestine” is a medicine that has an anti-exudative, antipruritic effect, reduces capillary permeability, and prevents swelling of tissues. The drug has almost no sedative effect, in therapeutic quantities does not affect the rate of psychomotor type reactions . With oral administration, the medication undergoes rapid and almost complete absorption. In plasma, maximum concentrations are reached after three hours. Eating simultaneously with the drug does not affect the bioavailability of the drug. The drug is metabolized in the liver. It is excreted through the intestines and kidneys.
Medication "Lordestine." Instructions for use. Indications
The tool is recommended for seasonal allergic rhinitis. The drug is prescribed, in particular, to eliminate symptoms such as rhinorrhea, sneezing, itching in the eyes and nose, redness of the eyes, lacrimation, cough, discomfort in the throat. The indications also include idiopathic urticaria of a chronic course, accompanied by a rash and skin irritation.
Means "Lordestine". Instructions for use. Contraindications
Do not prescribe medication under the age of twelve years, with individual intolerance to the components. Due to the fact that the drug is found in milk, treatment is not recommended for nursing patients. Means "Lordestine" instructions for use does not allow reception during pregnancy. Caution is exercised when prescribed to persons with severe renal failure .
Adverse reactions
The drug can cause drowsiness or insomnia, palpitations, psychomotor hyperreactivity, pain in the abdomen, tachycardia, hallucinations, hepatitis. Based on the treatment, dyspepsia (diarrhea or nausea before vomiting), anaphylactic shock, myalgia are likely. Instructions for use include hyperbilirubinemia, itching of the skin, rash, dysmenorrhea, angioedema, increased fatigue among the negative consequences of therapy with the medicine “Lordestine”.
Dosage regimen
The drug is prescribed orally. Five milligrams (1 tab.) Is recommended once a day for patients from the age of twelve. It is advisable to take the medicine at the same time, regardless of food. Do not crush (chew) tablets. For patients with hepatic or renal failure in the chronic stage, a dose adjustment is recommended. For these patients, the initial amount of medication is prescribed every day.
additional information
In practice, overdose cases are not described. Theoretically, drowsiness, increased adverse reactions from the gastrointestinal tract are likely. Recommended standard patient care measures. Hemodialysis with an overdose is ineffective.