Acne is a serious enough cosmetic problem that concerns not only boys and girls of adolescence, but also many people over 30. Acne can appear due to malnutrition, bad habits or hormonal failure in the body. In any case, self-medication should not be. A professional dermatologist will be able to establish the exact cause of skin problems, as well as pick up a good drug. Excellent results show the remedy "Roaccutane" from acne.
What is it like?
Roaccutane is a brown oval capsule filled with suspension. The main active ingredient is isotretinoid. As auxiliary substances, soybean oil, titanium dioxide are used. The capsule shell consists of gelatin, glycerol, potato starch and sorbitol. The drug is produced in various dosages - 10 and 20 mg. Means "Roaccutane" 10 mg is used for complex treatment of skin diseases. In more serious cases, an increased dosage is used.
The main substance of the drug (isotretinoid) belongs to the group of stereoisomers. The exact mechanism of action of this component has not yet been studied. Despite this, scientists were able to find out that isotretinoid helps to suppress the activity of the sebaceous glands. In addition, the substance affects the pore size and has an anti-inflammatory effect. The enlarged time, clogged with sebaceous secretion, is an excellent environment for the development of pathogens. Wrong do those who seek to get rid of the problem on their own. This only leads to the spread of infection. Although the tool “Roaccutane 20” does not give an instant result, but it allows you to get rid of acne on the skin forever.
Capsules not only reduce the production of skin secretion, but also contribute to the rapid differentiation of skin cells. This means that after removing the pimple, the wound heals completely without a trace. This helps to avoid troubles such as scars and pits on the face after acne.
Pharmacokinetics
How Roaccutane 10 will affect the skin condition can be judged from the first days of its administration. The fact is that the kinetics of the main active substance is linear. This means that isotretinoin does not affect the activity of enzymes that are involved in metabolism. The concentration of the drug in the blood is quite low. The main substance is largely absorbed into the plasma. The maximum concentration is achieved only 4 hours after taking the medication. Fasting is not recommended to take the drug "Roaccutane". Admission with food provides better absorption, which means that the result can be seen much faster.
Isotretinoin is excreted without problems with urine and feces. A day after the use of the drug in the patient’s body, there are no more substances that make up the Roaccutane preparation. The use of the drug should definitely be discussed with the doctor for those patients who have liver problems. Perhaps another medication will be prescribed or the dosage simply reduced. Renal failure does not affect the absorption of isotretinoin. Therefore, this disease is not a contraindication.
Indications and contraindications
Remedy "Roaccutane" from acne is not always used. The drug is used only in severe clinical cases, as well as when gentle treatment does not give the desired result. For the treatment of small acne, as well as to reduce oily skin, the pore size of the medication is not used. Roaccutane capsules can only be prescribed by a dermatologist who has experience working with systemic retinoids. This drug is quite potent. Independent use of it can lead to serious consequences.
The drug has a number of contraindications. It is not prescribed for children under 12 years of age, as well as for patients with liver failure, hypervitaminosis, obesity, diabetes mellitus, and chronic alcoholism. It is forbidden to donate blood to people who have been taking Roaccutane medication for a long time. The instruction for use states that the substance is completely excreted from the body only after a month.
During the period of treatment with the drug, each patient should monitor liver function. In order to avoid unpleasant consequences, it is periodically necessary to donate blood and urine for analysis. The doctor pays special attention to the concentration of lipids in the blood. If their content is increased, the drug is canceled completely, or its dosage is reduced.
Use during pregnancy
Fetal bearing is a serious contraindication to the use of Roaccutane. If pregnancy occurs during treatment or a month after the end of the course, there is a serious risk of having a baby with pathologies. In most cases, dermatologists recommend terminating the pregnancy. Doctors do not recommend women of childbearing age to take Roaccutane capsules. Instructions for use describe all possible contraindications. Prescribe the drug only when a woman suffers from a really strong form of acne and other medicines do not give a good result. In this case, the patient should be familiar with the consequences in the event of pregnancy, and also carefully follow all the instructions of the doctor.
The main substance of the drug is characterized by a strong teratogenic effect. During pregnancy, this leads to serious fetal malformations. Contraindication is also breastfeeding. A woman should decide what is more important for her. Having fed a healthy child for about a year, it will be possible to tackle their own cosmetological problems. Before prescribing the drug “Roaccutane”, the specialist is obliged to ask the woman about the marital status and the presence of babies. A dermatologist may also require a pregnancy test.
Dosage
It should be taken strictly according to the instructions of the Roaccutane capsule. Treatment begins with one capsule per day with meals. Depending on the form of the disease and individual characteristics of the patient, the doctor may prescribe the drug in a dosage of 10 or 20 mg. For most patients, the dosage is calculated as follows: 0.5 mg per 1 kg of body weight. If there are visible results, the doctor may increase the dose.
For one course of treatment, the patient can take from 120 to 150 mg of the drug. After some time, therapy should be repeated. If the patient has a tendency to remission, you can take several courses at once. In any case, treatment should be prescribed only by a doctor. If the patient does not tolerate the dose prescribed by the doctor, the course of treatment may be longer. In this case, you will have to take a drug with less active substance. In addition, you can replace the drug "Roaccutane." Good analogs are presented in almost every pharmacy. The doctor will be able to suggest the most suitable option.
Overdose and interaction with other medicines
If you take the drug strictly as prescribed by the doctor, no unpleasant sensations should arise. An overdose leads to the appearance of symptoms of poisoning and hypervitaminosis. In rare cases, you can not do without washing the stomach. If you experience dizziness, nausea and vomiting, you should immediately consult a doctor. Routine intolerance to Roaccutane capsules may occur. The doctor will be able to pick up the analogues of the drug quickly, and treatment will continue without consequences.
Due to the fact that the medication can lead to the development of hypervitaminosis, it is not recommended to take it together with vitamin A. You can not take the drug "Roaccutane" also with tetracyclines. The interaction of these medicines can lead to increased intracranial pressure. Isotretinoin, among other things, also weakens the effect of progesterone on the body. Therefore, contraceptives with this substance together with Roaccutane capsules are not recommended.
Side effects
In most cases, the side effects of the drug are related to the dosage. If the drug is taken as directed by a doctor, discomfort does not occur. In rare cases, mild nausea and dizziness may appear. But these phenomena are reversible. Dose adjustment can significantly improve the well-being of the patient. In rare cases, Roaccutane may be discontinued. Analogs, reviews of which are the best, are prescribed by dermatologists in the first place.
In rare cases, taking Roaccutane is accompanied by psychological problems, such as mood swings, depression. Less commonly, intracranial pressure rises and vision deteriorates. Any obscure symptoms should be reported to your doctor. The specialist can replace the drug "Roaccutane" with an analog. A pharmacy is available in every medical institution. Therefore, the patient will be able to resume treatment with another medication as quickly as possible.
Storage conditions
Roaccutane capsules can be stored for 3 years from the date of release. The package must contain information on the date of production. The product must be stored in a place inaccessible to children, at a temperature not exceeding 25 degrees. Do not place capsules in direct sunlight. If the drug has become sticky or its color has changed, it is not recommended to use it.
Roaccutane: analogues in Ukraine
If, for a number of reasons, the drug cannot be prescribed, the doctor will be able to choose other high-quality drugs for the treatment of acne. There are many drugs that can completely replace the Roaccutane capsules. Analogs are presented in pharmacies in a wide range. Aknekutan, which is also based on isotretinoin, is popular. It is also a capsule with a dosage of the active substance 8 mg. The drug is prescribed when a radical treatment is not necessary. The drug "Aknekutan" quickly and effectively treats light forms of acne.
Like Roaccutane, analogues are contraindicated in women during pregnancy and lactation. Isotretinoin, which is part of the composition, can lead to severe fetal damage. It is not recommended to take the drug for children under 12 years of age, as well as for people suffering from liver failure, diabetes mellitus, chronic alcoholism. In rare cases, increased sensitivity to the components of the drug is possible. It is not recommended to take the medicine "Aknekutan" in parallel with tetracyclines. During treatment, liver function should be constantly monitored. Like Roaccutane, analogues are taken only under medical supervision. It is necessary to periodically take blood and urine for analysis. In case of detection of an increased content of lipids, therapy is stopped.
Sotret is another popular medicine that can replace Roaccutane. Photos of patients speak for themselves. Within a month, the number of foci of inflammation on the skin is significantly reduced. Do not prescribe "Soot" capsules for women during pregnancy, as well as for patients with hypervitaminosis A, liver failure, and diseases of the rectum. Like Roaccutane, analogues should not be taken with tetracyclines. The specialist should pick up antibacterial drugs from another group.
What should be remembered?
"Roaccutane" is a specific drug that gives really good results. But taking it, you should adhere to some rules. Isotretinoin, which is part of the drug, affects the functioning of the sebaceous glands. Skin secretion begins to be produced in a much smaller volume. The amount of acne, of course, decreases. But the skin becomes defenseless against many environmental factors. The skin of the face must be properly moisturized if you have to take Roaccutane capsules. Photos of patients show that the face looks beautiful only with proper care. Cosmetics should be not only high-quality, but also hypoallergenic. For a moisturizer, it is best to consult a dermatologist.
In the summer, it is not recommended to use the product "Roaccutane". Sunlight is an additional stress for the skin. The face becomes photosensitive. This means that other problems will be added to acne. In spring and autumn, you should not go outside without protective cosmetics.
Retinoid therapy is a serious blow to the liver. During the treatment period, it is worth eating only healthy foods and abandon bad habits. Isotretinoin is almost completely processed by the liver. The use of additionally any medications can lead to serious consequences.
During the application of Roaakutan, the skin becomes much thinner. Any damage heals much longer, scars may remain. You should treat your skin with special care, handle sharp objects carefully. These are only temporary measures. It will take quite a while, and the skin will again shine with health. Isotretinoin also affects the musculoskeletal system. During the treatment period, it is much easier to make a fracture or a serious sprain. Serious sports are best left for later.