"Rumikoz" is a popular drug that treats fungus. The product has a wide range of effects, because it helps to get rid of various types of fungal ailments. Many people know about this tool, but not everyone is familiar with the instructions of "Rumikoz", and even before the start of use, it would not hurt to learn more about the product itself.
What is the composition of the product?
Each capsule or tablet of this drug contains one hundred milligrams of the active substance, and in this case itraconazole. Also in the composition of "Rumikoz" there are the following components:
- lutrol;
- sucrose or, in other words, sweetener;
- wheat starch.
All of these ingredients complement the action of the main component.
What are the medicinal properties of the drug?
The drug "Rumikoz" refers to substances such as triazole, which means that the product has a wide spectrum of action. Itraconazole is present in the product, and this product inhibits the creation of ergosterol, which is present in the structure of the cell membrane of pathogenic cells of the body. The active ingredient of the product is active against a number of microorganisms. This is a dermatophyte, a yeast-like fungus, as well as mold fungi.
If you use the drug orally, then there will be an early absorption by the mucous membranes in the gastrointestinal tract, and the highest coefficient in the bloodstream can be seen after four hours after the drug was taken.
If you want to achieve good results and get the highest bioavailability parameter, you will need to take the drug immediately after eating. After a week or two, it will be possible to observe the equilibrium concentration of itraconazole in the bloodstream.
The active component of the agent will accumulate in keratin tissue, and its excretion rate will directly depend on the regenerating features of the epidermis layer. As soon as two or three weeks pass, the necessary level of concentration of antifungal substance in tissues and mucous membranes will be saved. In this case, all metabolic mechanisms will occur in the liver and at the same time, the active production of metabolites will occur.
This drug is distributed over various tissues in the human body, its highest concentration will be observed in the bones, liver, spleen, lungs, and only then in the bloodstream.
What is the release form of this medicine?
The tool is available in the form of tablets and capsules. At the same time, Rumikoz capsules, like tablets, contain about one hundred milligrams of the active substance itraconazole. Each package contains five or six capsules, the same is available in tablets.
The presented preparation is characterized by a pronounced antifungal effect against many known and common strains. Only a qualified specialist is allowed to prescribe this tool.
Features of the tool
As part of the medicine, there is an active substance that prevents the development of ergosterol, which allows the fungal disease to multiply. As soon as the growth and development of a given substance is stopped, the disease stops developing and, as a result, is eliminated.
It is worth noting that the medicine is perfectly absorbed in the digestive tract, but it is better to take it after a meal. In this case, the active component of the drug binds perfectly to proteins in the bloodstream.
In the nail plate, the active substance will begin to appear only a week after the start of treatment, and after six months it can also be detected in the human body, even if the treatment is already completed.
An interesting fact: the drug can also penetrate into the sebaceous and sweat glands in the human body.
The destruction of this component is carried out in the liver, however, all its metabolites remain active. Up to 20% of the drug is excreted through the intestines, less than a percent in an unchanged state is excreted through the kidneys, and 35% is also removed by the kidneys, but the substance will already be in a destroyed state.
It is worth noting that the drug is much worse absorbed in patients who have immune disorders. Which ones? This, for example, AIDS, renal failure, organ transplantation. If you suffer from cirrhosis of the liver, then your bioavailability will be reduced, and the time to remove the drug from the body will be long.
What are the indications for the use of the drug?
Before use, you should find out what indications Rumikoz has. Prescribe a drug product with:
- cryptococcosis or, in other words, with cryptococcal meningitis ;
- pityriasis versicolor;
- fungal keratitis, systemic mycoses, as well as onychomycosis;
- dermatomycosis, candidiasis in the mucous membranes and on the skin;
- systemic forms of candidiasis, aspergillosis, histoplasmosis, sporotrichosis, blastopicosis, paracoccidioidomiasis and other tropical mycoses.
In treatment, you can choose not only capsules, but also another form. There are tablets "Rumikoz". Choose for yourself what is more convenient for you to use, and be treated.
How is the drug used and what doses are allowed?
The instruction "Rumikoz" is extensive, it all depends on the ailment. The drug is intended for oral administration, capsules or tablets should be swallowed whole (do not chew them and do not share). Drinking the medicine after meals is recommended. The duration of treatment and dosage is determined by the attending physician. However, you can give the standard instruction "Rumikoz" for some diseases:
- Vulvovaginal candidiasis. There are two methodologies for treating this disease. In the first scheme, the patient is prescribed a two-milligram drug twice a day, and the therapy lasts a day. The second method involves taking the medicine for three days at two hundred milligrams.
- Oral candidiasis. In this case, the instruction "Rumikoz" will be the following - one hundred milligrams per day, take the drug for fifteen days.
- Fungal keratitis, dermatomycosis, pityriasis versicolor. If you suffer from such ailments, then you need to drink two hundred milligrams of this remedy per day. Treatment will continue in different ways: with dermatomycosis and lichen - a week, with keratitis - twenty-one days. If you have advanced dermatomycosis, you will have to be treated for two weeks.
- Onychomycosis. In this case, you will need to take two hundred milligrams of the drug daily for seven days. Then you need to take a three-week break, and then repeat the course of treatment. If the nail plate is severely affected, then it is better to undergo a couple of continuous courses of treatment, if you have onychomycosis on your legs, then you need to undergo three courses of treatment. There are extremely neglected cases when treatment can last up to three months.
- The defeat of highly keratinized zones. Four hundred milligrams of products per day will be required in two sets - this is a week, and then for a month, one hundred milligrams of products will be consumed daily.
- Mycoses of a systemic nature. Usually, treatment is carried out with the intake of one to four hundred milligrams, and the duration of therapy is from three weeks to eight months. If you suffer from aspergillosis, then the daily intake of the drug will be two hundred milligrams and will have to be treated from two to five months. With cryptococcosis, you will need to drink two hundred milligrams of the drug daily for up to a year. With sporotrichosis, you need to drink one hundred milligrams of the drug for three months. Histoplasmosis - it is necessary to take two hundred milligrams twice a day, therapy lasts for eight months. Cryptococcal meningitis - should be consumed four hundred milligrams of the drug per day, therapy lasts up to two months. Blastomycosis - you need to drink from one hundred to four hundred milligrams of the drug for six months. Chronomycosis - the daily dose of the drug is one hundred to two hundred milligrams, the medicine is taken for six months. Paracoccidioidomycosis - a day you will need to drink one hundred milligrams of the drug, you need to take the drug for six months.
- Thrush. If you suffer from this ailment, then it is recommended to drink the medicine for one hundred to two hundred milligrams throughout the day, the duration of treatment is from one to seven months.
It is worth noting that if the patient suffers from AIDS or has had an organ transplant, then the dosage will need to be adjusted individually, this will be done by your doctor. As you can see, the indications of "Rumikoz" are extremely extensive, but caution is always necessary with medicines - side effects may not keep you waiting.
Can there be side effects after taking the drug?
Yes, "Rumikoz" with nail fungus or other ailments is extremely effective, but do not forget about unwanted reactions. During treatment, a person may experience the following side effects:
- in the gastrointestinal tract: vomiting, pain in the epigastric zone, nausea, anorexia, digestive upset, impaired stool;
- in the central nervous system: dizziness, headaches;
- allergic manifestations: Quincke's edema, rashes, itching, urticaria, anaphylactic shock;
- in the liver and biliary tract: hepatitis, toxic effects on the liver, liver failure, stimulation of the production of liver enzymes;
- in the skin: photosensitivity, alopecia;
- different edema, menstrual irregularities, dark color of urine, decreased potassium in plasma.
To avoid all this, you will need to strictly adhere to the dosages prescribed by your doctor and know what contraindications Rumikoz is.
In what cases is it forbidden to use the product?
The tool is forbidden to use for people who suffer from hypersensitivity to any components that are in the composition. It is also worth knowing that “Rumikoz” is not available in the form of ointment. Caution is required to take the medicine for patients suffering from chronic liver ailments, renal or heart failure. For children, the drug is prescribed in exceptional cases, and treatment is carried out under the supervision of a doctor.
All due to the fact that the active substance of the drug can have a negative inotropic effect. At the same time, this product can affect the metabolism of calcium channel blockers, slow down the excretion of calcium from the body, therefore it is necessary to carefully take the medicine.
Points to Know About in Advance
If you suffer from kidney failure, then this ailment can significantly reduce the bioavailability of the drug, because only with the permission of the doctor is allowed to drink this medicine and always adhere to the dosage.
Treatment will need to be immediately canceled with the development of neuropathy, which is caused by this medicine. If you suffer from low acidity in the stomach, then the absorption of the drug will occur with obvious violations. If it is necessary to take antacids, then this should be done only a couple of hours after "Rumikoz".
Do you suffer from achlorhydria or are you taking proton pump inhibitors or histamine H2 receptor blockers? Then the medicine should be taken with acidic drinks.
In rare cases, after treatment with "Rumikoz" people expressed severe liver damage. This was in patients with already existing hepatic pathologies, as well as in patients receiving drugs with hepatotoxic effects.
An increase in the dose of the medicine may be required for those who suffer from impaired immune systems. The tool should not be given to children.
What to do during pregnancy and lactation?
The presented drug is prescribed for pregnant women only for health reasons, all due to the fact that the medicine can have a negative effect on the fetus. Women of reproductive age when using a medicinal product are recommended to deliberately exclude the possibility of pregnancy in order to fully recover, and only then think about the birth of a child.
If you are a young mother, and the doctor has prescribed this drug for you, then breast-feeding will have to be stopped.
What is the cost of the drug?
The price of "Rumikoz" in each pharmacy is different. The cost starts from four hundred rubles per package (there are 5-6 capsules). Quite an expensive medicine, given that the course of treatment can be months, but the remedy is effective, this is evidenced by the reviews of grateful patients who were helped by the medicine. Despite the fact that the price of Rumikoz is high, the drug is actively in demand.
How to store medicine?
"Rumikoz" will need to be stored in a dark, dry and cool place. Shelf life of the drug is three years. You can see the production date on the packaging. Always store the medicine correctly, because improper storage will lead to the fact that the drug will deteriorate and will not bring a positive result at all.
What product analogues exist?
The drug "Rumikoz" analogues, of course, exist. The following drugs are referred to drug analogues for the active substance: Orungal, Itrazol, Irunin, Itramikol and Mikonyhol. The cost of drugs is different, there are drugs cheaper than Rumikoz, but you should not choose them if your doctor has prescribed you a specific remedy. As you can see, Rumikoz analogues are available in sufficient quantities, but the replacement of the medicine should always be discussed with the doctor. Do you want to recover completely? Then follow the recommendations of a specialist.
And what about the "Rumikoz" reviews?
People’s comments are different. The remedy helped some people, but not others. This is due to the fact that a lot of people do not adhere to the doctor’s recommendations and don’t drink the medicine as prescribed, which is why problems arise later. “Rumikoz” helped many girls to get rid of the fungus on the nails of their hands and feet, and returned confidence in their own beauty. Many praise the drug for its quick action, although not everyone likes the price.
Many girls are happy with the remedy, because they quickly discovered a developing fungus and managed to completely get rid of a developing ailment with the help of this drug in several applications.
As you can see, the reviews about Rumikoz are different, so it's up to you to decide whether to buy the drug. However, if your doctor has prescribed it for you, then you should not neglect the recommendations of a specialist, it is better to strictly follow them. Moreover, many doctors recommend the use of “Rumikoz”, because the remedy has shown itself to be excellent for a long time, and there is simply no reason to refuse an effective drug.
To summarize
"Rumikoz" is an effective drug that many people choose today. If you adhere to the prescribed dosages, then everyone can recover from the disease in a short time, the main thing is to make every effort to this.