The modern medicine "Prednisolone" refers to drugs with a wide spectrum of action. This remedy can be prescribed to patients, for example, with inflammation of the gastrointestinal tract, hepatitis, multiple sclerosis. Quite often, Prednisolone is prescribed for asthma.
The composition and form of the drug
This tool belongs to the group of glucocorticosteroids hormonal drugs and the effect on the patient's body has a similar effect to hydrocortisone. At the same time, it is several times superior in activity to this popular medicine. Prednisolone may be produced in the form of:
- pills
- solutions for intravenous and intramuscular administration;
- ointments for external use;
- eye drops.
In asthma, Prednisone is prescribed to patients in the first two forms. Ointments are used for joint diseases. Drops are used for inflammation of the eyes. The main active ingredient of all varieties of this medication is prednisone.
Tablets of this remedy are in pharmacies about 68 p. Additionally, this form of Prednisolone contains substances such as:
- calcium stearate;
- milk sugar;
- potato starch.
The cost of the injection for this drug can range from 46-130 r. In addition to prendizolone, they include such components as:
- nicotinamide;
- sodium hydroxide;
- water for injections.
Indications for use
In addition to bronchial asthma, this tool can also be used for treatment with asthmatic status. In both of these cases, the medicine helps, judging by the reviews, very well. But asthma, as already mentioned, is not the only disease in which "Prednisolone" is prescribed. This drug is also used if the patient has, for example, problems such as:
- acute and chronic allergies;
- inflammatory joint diseases;
- skin diseases: eczema, dermatitis, etc.
- cerebral edema;
- inflammation of the eyes;
- adrenal insufficiency;
- diseases of the blood;
- pulmonary tuberculosis;
- tuberculous meningitis;
- multiple sclerosis;
- lung cancer;
- hepatitis;
- ulcerative colitis, etc.
When not to take
A feature of this medicine is that in emergency cases it is administered without taking into account various kinds of contraindications. Long-term treatment with Prednisolone, like with almost any other medication, is, of course, not always possible. Contraindications to the use of this medication can become, for example, with prolonged treatment:
- osteoporosis;
- stomach ulcer;
- diabetes;
- all kinds of psychoses;
- polio;
- AIDS;
- Cushing's syndrome;
- severe arterial hypertension.
If the patient has problems such as acute renal or hepatic insufficiency, it is necessary to use Prednisolone for bronchial asthma strictly under the supervision of a doctor.
When else should be taken under the supervision of a specialist
With caution, only in the most extreme cases, in case of emergency, "Prednisolone" in asthma, as in other diseases, can also be prescribed:
- pregnant women in the first trimester (prolonged treatment using this drug disrupts the process of fetal development);
- lactating women;
- children under 18 years old.
In the latter case, the medicine can be prescribed for treatment for a long time. However, at the same time, it is supposed to conduct a thorough preliminary examination and undergo consultation with several specialists at once.
In addition, with caution, this medicine is prescribed for:
- ulcers, gastritis and colitis;
- heart attack, heart failure, high blood pressure;
- with infectious diseases;
- 8 weeks and 2 weeks after any vaccination;
- with glaucoma.
Important
In no case should you prescribe this tool yourself on your own. You can take Prednisolone far from all drugs at the same time. Choosing the wrong treatment with this remedy can lead to extremely negative consequences, even death. Before you start a course using this drug, you should definitely visit a doctor. If any negative reactions of the body occur during the use of this agent, this should also be reported immediately to a specialist.
What is the drug for asthma
The treatment of asthma with Prednisolone becomes possible primarily because it:
- able to have anti-inflammatory and anti-allergic effects;
- eliminates and significantly reduces swelling of the mucous membranes;
- limits connective tissue reactions;
- inhibits erosion of the mucosa;
- reduces the likelihood of scar tissue formation.
Once in the human body, the active substance of this drug increases the sensitivity of beta 2-adrenergic receptors of small and medium bronchi to catecholamines and sympathomimetics, inhibits the synthesis of adrenocorticotropic hormone. Also, this medicine can reduce the viscosity of mucus.
Side effects
As already mentioned, Prednisolone is able to exert a negative effect on the patient’s body. Most often during treatment with its use in patients, the following side effects appear:
- vomiting, nausea, bloating, loss of appetite;
- heart rhythm disturbances;
- headaches, sleep disturbances, cramps;
- the development of diabetes;
- the formation of Itsenko-Cushing's syndrome;
- weight gain;
- sweating and swelling;
- allergic reactions.
What will happen in case of an overdose
Of course, this medicine can be taken only as directed by a doctor and under his supervision. The dose of Prednisolone in asthma, chosen by a specialist, can not be exceeded in any case.
If the patient will be injected with too much solution of this drug, or he will take many tablets, he may have an increase in the side effects listed above. Unfortunately, a specific scheme to eliminate intoxication of the body with this medicine was not developed. Treatment with an overdose is usually carried out only symptomatic.
Instructions for use of the solution for bronchial asthma
To treat this disease, the liquid form of Prednisolone is used quite often. Injections are usually prescribed during hospital treatment.
Dosages of Prednisolone in asthma are selected by the doctor individually, depending on the condition of the patient and his weight. During the course of the patient, 75 to 675 mg of the drug can be administered. Only with serious complications, the amount of the drug is sometimes increased to 1400 mg. The intervals between doses of medicine are also prescribed individually by a specialist. As soon as the patient's condition improves, the dose is gradually reduced.
Instructions for asthmatic status
In this case, initially the patient is administered 500-1200 mg of the drug per day. When the patient's condition improves, the dose is gradually reduced to 300 mg per day. Subsequently, they switch to maintenance treatment. In this case, the doctor sets the dosages individually.
Directions for use for tablets
Very often with asthma "Prednisolone" is prescribed to patients in this form. The first course of therapy when using tablets according to the instructions should not last more than 16 days. They usually begin to treat asthma by taking 5-6 mg of the drug per day. After stabilization, the dose is reduced to 3 mg.
Maintenance therapy using this medication is carried out in an amount of 1.5-2.5 tablets per day, 1 time per day. It is also allowed to take a double dose of the drug every other day. During exacerbation of bronchial asthma, Prednisolone tablets, like its liquid form, can be prescribed in an amount up to 1400 mg for the entire course.
How to take
The release of glucocorticoids in the human body occurs, as you know, cyclically. Therefore, Prednisolone is supposed to be taken during the period of active wakefulness, that is, from 8 am to 6 pm. At the same time, many doctors believe that the greatest effect of using this drug will be achieved if it enters the patient's body at noon - from 13:00 to 15:00. It is at this time that the active suppression of bronchopulmonary fluid occurs.
It is supposed to gradually reduce the dose of the drug during treatment. Abrupt cessation of the amount of Prednisolone taken can, unfortunately, lead to exacerbation of bronchial asthma.
As you can see, this remedy gives a lot of side effects. Therefore, patients in the treatment of bronchial asthma "Prednisolone":
- periodically undergo blood pressure monitoring, the level of electrolytes and water in the body;
- are under the supervision of an optometrist;
- periodically take a blood test for sugar.
In order to reduce the risk of side effects, in combination with this drug, patients may be prescribed medications containing male hormones. To prevent heart problems, the patient is also often prescribed pharmaceutical potassium or preparations made on the basis of this substance.
Interaction with other medicines
Combining this drug is not allowed with all medications. For example, you should avoid the simultaneous use of the solution and tablets of Prednisolone in asthma with:
- diuretics and Amphoricin B, since this increases the risk of heart failure;
- cardiac glycosides, which may exacerbate hypokalemia;
- immunosuppressants, as this can provoke the development of infectious diseases;
- m-anticholinergics, which can cause an increase in intraocular pressure;
- anticoagulants, non-steroidal anti-inflammatory drugs, as this increases the risk of gastric bleeding;
- paracetamol and cyclosporine, as this increases the likelihood of toxic liver damage.
Patient Reviews
The drug "Prednisolone" with asthma attacks is used quite often and is considered a very powerful tool. It is usually prescribed in severe cases. It helps with asthma, as many patients note, better than most other medicines used for the same diseases. But you need to drink it, according to doctors and patients, only if it is really necessary. This medicine actually gives a lot of side effects. Patients undergoing treatment using this medication often have to start taking various kinds of additional drugs to support other organs that they have a negative effect on. And this, in turn, of course, does not affect the condition of the liver in the best way.
Prednisolone is produced today by many pharmaceutical companies. At the same time, this drug produced by the St. Petersburg company Severnaya Zvezda deserved the best reviews. However, unfortunately, it is difficult to find a drug from this manufacturer today, judging by the reviews.
Analogues of the drug
"Prednisolone" with bronchial asthma and bronchitis is able to help patients very well. But if necessary, tablets and ampoules of this drug can be replaced, for example, with such means as:
- Prednisone
- Medopred;
- "Prednisolone Nycomed."
Also, asthma is sometimes treated using an analogue of this drug, Prednisolone Gemsuccinate. You cannot replace this medicine on your own with any drugs with a similar therapeutic effect. If necessary, the analogue should be selected exclusively by the attending physician.