In the article, we consider the instructions for use and analogues of Cabergoline.
This drug is a medication that effectively lowers prolactin. This tool is a structural analogue of some derivatives of ergotamine.
About the drug
"Cabergoline" is a domestic drug. The medicine is produced in tablets of 0.5 milligrams. One package contains two or eight pills. This medicine can stimulate dopamine receptors, inhibits the production of prolactin and reduces its content in the blood.
The presented drug eliminates the manifestation of excess prolactin, such as oligomenorrhea and amenorrhea, decreased libido, impotence, infertility and inhibition of breast milk formation. The drug can also reduce extrapyramidal disturbance, affecting dopaminergic transmission. It is used for patients with increased prolactin levels. This drug is also used in the presence of pituitary adenoma in order to eliminate menstrual irregularities. Instructions for use with "Cabergoline" confirms this.
Dosage and duration of use largely depend on the goals of therapy. "Cabergoline" is able to cause allergic reactions along with dyspeptic symptoms, headaches, dizziness, general weakness, psychosis, sleep disturbances and so on. This medicine has contraindications. The cost of the funds ranges from three hundred to seven hundred rubles.
What are the cheap analogues of Cabergoline?
Bergolak
One of the analogues of the drug in question is a drug called "Bergolac". The cost of this substitute ranges from two hundred to eight hundred rubles. This analogue is synonymous with Cabergoline. It is produced by the Russian company Veropharm. The drug is in the form of tablets. This drug has the same active substance, and in addition, the same mechanism of action.
Bergolak is used to treat menstrual irregularities, to eliminate impotence, sexual drive disorder and infertility, which is caused by secondary and primary hyperprolactinemia. In addition, this tool is used to suppress milk production after childbirth and against the background of established lactation if there is a medical indication for this.
Also, this analogue of the drug “Cabergoline” eliminates the severity of the manifestation of a decreased blood estrogen content (we are talking about obesity, osteoporosis, edema, and so on). The dosage of this drug depends on the goals of treatment and the level of progesterone in the body.
The analogue of Cabergoline is capable of causing a skin rash in people with itching and pain. Bloating is not ruled out, along with nausea, vomiting, upset stools, general weakness, dizziness, and increased activity of liver enzymes. Also, in patients with its use, drowsiness is observed in combination with paresthesia, visual field disturbance, leg swelling, heart pain, lowering blood pressure, tachycardia, baldness and muscle cramps.
This drug is contraindicated for its intolerance, and, in addition, in the case of severe pathologies of the liver and lungs, with psychosis and disease of the peripheral arteries. You should also not take it for stomach ulcers, in childhood, and for women bearing a child.
Analog "Agalates"
This analogue of Cabergoline will cost consumers five hundred rubles. The medicine "Agalates" is also a synonym. It is produced by the Czech company Teva in the form of tablets. The active substance in this case is also cabergoline.
This medicine stimulates dopamine receptors in people, inhibits the formation of prolactin, and in large doses reduces extrapyramidal disorders. The drug perfectly eliminates the violation caused by an increased amount of prolactin. Thus, under its influence, amenorrhea is treated along with oligomenorrhea, libido disorder, impotence and infertility.
This analogue is used in the presence of idiopathic hyperprolactinemia, which is caused by pituitary adenoma, and it is also often used to suppress lactation. This substitute can be used to treat Parkinson’s disease and if a person has secondary Parkinsonism.
It is worth noting that the drug in question can provoke general allergic reactions along with impaired functioning of the digestive system. Against the background of its use in patients, such adverse reactions as increased transaminase activity, hypotension, accelerated heart rate, dizziness, the appearance of drowsiness and general weakness are observed. Also, syncope along with visual impairment, peripheral edema and cramps in the muscles of the legs are not excluded.
You can not use this medicine if it is intolerant, and, in addition, against the background of severe liver pathologies, with psychosis, pleurisy and severe pneumofibrosis. The drug is prohibited for pregnant women and patients who are breastfeeding in the absence of medical indications.
Which analogue of Cabergoline to choose, the doctor will tell.
Dostinex
This substitute will cost consumers six hundred rubles. This drug is produced by the pharmaceutical company Pfizer. The medicine is German and is produced in the form of tablets, which also contain cabergoline as their active component.
The analogue of Cabergoline perfectly stimulates dopaminergic transmission and inhibits the production of prolactin. It is used to treat patients suffering from high levels of prolactin in the body. Thus, this drug is used in a number of the following clinical cases:
- If the patient has Turkish saddle syndrome.
- Against the background of the development of primary hyperprolactinemia.
- In order to stop the production of breast milk after childbirth.
- In the presence of amenorrhea and oligomenorrhea.
- Against the background of impotence and infertility.
While taking this drug, patients may experience some allergic reactions along with dyspeptic symptoms, dizziness, drowsiness, general weakness, hypotension, tachycardia, peripheral arterial spasms, leg swelling, calf muscle cramps, sensitivity disorders, and increased liver enzyme activity.
The presented remedy is contraindicated in the presence of idiosyncrasy and against the background of severe liver pathologies. Also, it should not be used for diseases such as severe pathologies of the peripheral arteries and heart, severe pneumofibrosis, psychosis, and severe cognitive changes. Dostinex is prohibited for pregnant women and children.
What else is included in the list of analogues of Cabergoline? You can also purchase funds such as Alactin, Caberlin.
Indications for use
Indications for taking this medicine are the following appointments and deviations:
- In order to prevent or suppress postpartum lactation.
- In the presence of hyperprolactinemia, accompanied by a violation of the cycle. For example, the drug is prescribed to patients with amenorrhea, oligomenorrhea and anovulation.
- Against the background of the presence of galactorrhea, infertility, impotence and a decrease in libido in men.
- In the presence of prolactin-secreting pituitary adenomas.
- In the case of idiopathic hyperprolactinemia.
- With the syndrome of the Turkish saddle.
- With acromegaly as part of maintenance therapy after radiation therapy and surgery.
What else does the application instruction for Cabergoline tell us?
Contraindications
As contraindications, the following pathologies are given:
- The presence of hypersensitivity to ergot derivatives.
- The period of pregnancy along with postpartum psychosis.
- In the period of postpartum hypertension.
- In the presence of preeclampsia.
- In children under the age of sixteen, since safety and efficacy have not yet been established.
With caution, this drug is taken in the presence of arterial hypertension, coronary heart disease, kidney failure, and, in addition, in the case of severe mental illness.
Side effects
Adverse reactions when taking this drug are usually mild and occur within the first two weeks, and usually go away on their own:
- The nervous system can react with dizziness, headache, insomnia, and in the case of prolonged use, weakness is possible along with drowsiness, depression, asthenia, paresthesia, and fainting.
- The digestive system may be accompanied by nausea, dry mouth, pain in the epigastric region, and in case of prolonged use, vomiting with constipation and the development of gastritis is likely.
- Perhaps a decrease in pressure and the development of orthostatic hypotension.
- Nasal bleeding, flushing of the face along with transient hemianopsia, twitching of leg muscles, allergic skin reactions, and so on are not ruled out.
Method of administration and dosage of medication
The presented drug is taken orally while eating. In order to prevent postpartum lactation in the first day after birth, take one milligram of the drug once. In order to suppress established lactation, they use 0.25 milligrams twice within two days. As part of the treatment of hyperprolactinemia, 0.5 milligrams is used twice a week. The therapeutic dosage is from 0.25 to 2 milligrams per week. The average therapeutic dosage is 1 milligram per week in two divided doses. The maximum weekly dosage is 4.5 milligrams.
Reviews
In reviews of the drug Cabergoline, people write that this drug effectively lowers prolactin. But, according to patients, against the background of its use, one or another adverse reaction can often be observed.
Comments on analogues
As for the analogues of Cabergoline, consumers also speak of them as effective medicines. True, they express dissatisfaction with the frequent occurrence of side effects.
We reviewed the instructions for use for "Cabergoline", reviews and analogues.