For what deviations can Zinnat medication be prescribed by doctors? Analogs of this drug, its pharmacological properties and instructions for use will be presented below. We will also tell you about whether this product has contraindications and side effects, in what forms it goes on sale, what composition and properties it has, what is its cost and so on.
Forms of release of the drug and their composition
In what form can you find the Zinnat medication in a pharmacy? Its analogues are made in different forms. As for the drug itself, it can be purchased in the form of tablets and granules for the preparation of a suspension. Consider the composition of these drug options in more detail:
- Zinnat tablets. The instructions attached to the drug states that all tablets are coated with a special coating. This medicine contains an active element such as cefuroxime. In addition, the Zinnat medication (125 and 250 mg) includes some auxiliary components. These are: hydrogenated vegetable oil, croscarmellose sodium, colloidal silicon dioxide, microcrystalline cellulose, white Opaspray, sodium lauryl sulfate, propylene glycol, propyl parahydroxybenzoate and methyl hydroxypropyl cellulose, methyl parahydroxybenzoate. In a cardboard pack of a drug may be 5 or 10 tablets.
- The medicine "Zinnat" (suspension). These are granules intended for the preparation of a sweet suspension for the treatment of young children and adolescents. The made solution must be taken only inside. As in tablets, the active substance of this form of the drug is cefuroxime. Also, Zinnat medicinal granules (125 and 250 mg) also contain auxiliary components. These are potassium acesulfame, sucrose, purified water, povidone K30, stearic acid, aspartame, xanthan gum and children's flavor “Tutti-frutti”. The Zinnat preparation goes on sale in granules
in a bottle of dark glass in a volume of 50 ml. Also, for a more convenient use, the kit includes a dosage spoon and a measuring cup.
It should be noted that some pharmacological companies also produce Zinnat powder for intravenous and intramuscular administration.
Pharmacological properties of the drug
What pharmacological characteristics does the Zinnat drug (250 and 150 mg) have? The mentioned preparation is a second generation cephalosporin antibiotic intended for oral administration. It acts bactericidal, disrupting the synthesis of bacterial cell walls. The medication has a fairly wide spectrum of action. We can not say that it is resistant to many beta-lactamases.
The effectiveness of the drug against infections and bacteria
What bacteria are most effective for Zinnat (250 and 150 mg)? As a rule, it is very often prescribed against gram-positive aerobic bacteria such as Staphylococcus aureus and epidermal staphylococci (including strains that are resistant to penicillins and with rare exceptions of methicillin-resistant strains). Also, the drug is highly effective in pyrrolidonyl peptidase, pneumococci, group B streptococci and whooping cough.
In addition, the presented drug is often prescribed to combat aerobic gram-negative bacteria (Escherichia coli, Klebsiella SPP., Providencia SPP., Haemophilus influenzae and ampicillin-resistant strains).
It cannot be said that the Zinnat preparation is very effective against gonococci (strains producing and not producing penicillinase), meningococci, salmonella, and so on.
In addition, it should be noted that methicillin-resistant strains of Staphylococcus aureus golden and epidermal, Campylobacter SPP., Pseudomonas SPP., Listeria, etc. are resistant to the active substance - cefuroxime.
According to the studies of specialists, when combining the active component of the drug with antibiotics belonging to the group of aminoglycosides, an additive effect, and sometimes synergism, can be observed in patients.
Indications for the use of the drug
In what cases is the Zinnat antibiotic prescribed? The price of the drug in different forms is presented below. According to the instructions of the medication, it should be taken in the presence of such pathologies as:
- ENT infection. The drug is prescribed for tonsillitis (inflammation of the tonsils), pharyngitis (inflammation of the pharynx), acute otitis media (inflammation of the middle ear) and sinusitis (inflammation of the sinuses).
- Lower and upper respiratory tract infections. The drug "Zinnat" with angina helps very well. However, it is often prescribed in the presence of other diseases. These include postoperative infection of the chest, lung abscess (or the process of accumulation of pus in the lung tissue), infected bronchiectasis (that is, an expansion of the part of the bronchus that is irreversible), bacterial pneumonia, and chronic / acute bronchitis.
- Zinnat granules and tablets, the instructions for use of which contain complete information on the method of taking the medication, can be prescribed by a doctor for diseases of soft tissues and skin. These diseases include the following pathological conditions: phlegmon (or purulent inflammation of the fiber), erysipeloid (that is, an infectious lesion of the skin), furunculosis with the formation of many boils, wound infection in which pathogens, impetigo (that is, the formation of pustules) multiply in the tissues. caused by streptococcus and staphylococcus), erysipelas (severe inflammation of the skin caused by streptococcus), pyoderma (skin diseases that were triggered by pyogenic microorganisms isms).
- Infections of the genitourinary system. Zinnat medicine, analogues of this drug (if it is necessary to replace the described drug) can be prescribed for acute or chronic pyelonephritis (inflammation of the kidneys), urethritis (inflammation of the walls of the urethra), cystitis (inflammation of the bladder), asymptomatic bacteriuria (colonization by urinary bacteria) ways), gonorrhea (an infectious disease that is caused by gonococcus).
- Pelvic infections. The drug well treats cervicitis (i.e. inflammation of the cervix), endometritis (or inflammation of the uterine mucosa) and adnexitis (inflammatory processes in the uterine appendages).
- Diseases of the joints and bones. As you noticed, the use of Zinnat is quite extensive. It can be used not only to treat internal organs and skin diseases, but also bones. So, it is often prescribed to patients with septic arthritis (when bacteria enter the joint cavity) and osteomyelitis (with purulent inflammation of the periosteum).
- Also, the drug is very effective for meningitis (inflammation of the membranes of the brain and spinal cord), Lyme disease (transmitted through tick bites) and sepsis (that is, an infectious disease caused by bacteria, unicellular fungi or toxins entering the bloodstream).
In addition, with the help of the Zinnat medication, complications are also prevented during operations on the chest, abdominal organs, pelvis, and joints.
According to the reviews of patients and specialists, this drug is very effective in all of the above pathologies. But this is only if they were caused by bacteria sensitive to the drug. If there is no effect from taking the drug, then you should consult a doctor and undergo a medical examination again.
Contraindications to the use of the drug
The Zinnat medication, the photo of which is presented in this article, is not recommended for allergic reactions of the patient to penicillins, for hypersensitivity to the active substance (cefuroxime), as well as diseases and bleeding of the digestive system. Do not give it to children up to three months.
It should also be noted that the drug should be taken with special care by pregnant women (especially in the first trimester) and during breastfeeding.
The drug "Zinnat": instructions for use, price
After prescribing the mentioned drug, the doctor is obliged to explain to his patient how to use this medication. Also, before starting the reception, it is recommended that you read the attached instructions.
Zinnat tablets must be taken during or immediately after eating food. With angina and other diseases, the drug is recommended to be used for 5-10 days. In Lyme disease, the duration of patience should be at least 20 days.
In most cases, the Zinnat medication for angina and other infectious diseases is prescribed to adults in the amount of 250 mg twice a day. With pyelonephritis, an antibiotic is used with the same frequency, but in an amount of 125 mg.
If there is a suspicion of pneumonia, as well as Lyme disease, in severe infections of the respiratory tract, taking the drug in a single dose should not be 250, but 500 mg. At the same time, double periodicity is maintained. With gonorrhea (uncomplicated), the drug is recommended to be taken once a day in an amount of 1 g.
The drug "Zinnat" (suspension for children): instructions for use of the medication
In the event that treatment with this drug was prescribed to a child, then doctors recommend using granules intended for the preparation of a sweet suspension. It should be borne in mind that 10 ml of a liquid preparation corresponds to 250 mg of the active substance (cefuroxime).
At what dosage is the Zinnat (suspension) medication prescribed for children? The instruction for this tool states that a teenager over 12 years old is prescribed an antibiotic twice a day for 125 mg.
For children from three months to 12 years, a single dosage is calculated by multiplying 10 mg per kilogram of the child’s weight. The frequency of admission for babies remains the same as for adolescents.
In severe infectious diseases and otitis media, an adolescent over 12 years of age can be prescribed a drug in the amount of 250 mg twice a day, and for a child from three months old - 15 mg / kg (with a similar frequency).
Injectable form of the drug: instructions for use
Now you know how Zinnat (suspension) is given to the child. However, it should be noted that, in addition to granules and tablets, such a medication is available in the form of a powder for injection.
With intramuscular and intravenous administration to adults, an antibiotic is prescribed three times a day at 750 mg. If the patient has more severe forms of the disease, then the single dosage is doubled.
Children can also be injected with Zinnat. In this case, it is administered three times a day. In this case, the dosage is calculated by multiplying: 60 mg of the active substance x per kilogram of the weight of the teenager.
With clinical indications, you can switch from parenteral use of the antibiotic to a suspension or tablets.
Side effects after taking the medication
Are there any side effects after taking Zinnat? The answer to this question is contained in the instructions for the medication.
So, the following negative phenomena can be attributed to side effects after applying the aforementioned funds:
- fever, urticaria, and itching (appear on the skin), skin rash, and the development of anaphylaxis;
- hypoprothrombinemia, leukopenia, hemolytic anemia, thrombocytopenia and eosinophilia;
- hearing impairment, cramps, headaches, and drowsiness;
- diarrhea, increased activity of liver enzymes, vomiting, hepatitis, nausea and cholestatic jaundice;
- vaginosis, dysbiosis and interstitial nephritis.
It should also be noted that in patients' reviews about the mentioned medication, information is often found that after taking the drug, some representatives of the weaker sex have thrush. The appearance of such a deviation is due to the large growth of Candida group mushrooms during antibiotic therapy.
Special instructions for the use of the drug
If the drug has been used for a long time, then patients may experience increased reproduction of resistant microorganisms. As a rule, this requires immediate cessation of treatment.
It is no secret to anyone that taking anabiotic drugs very often leads to diarrhea. And the Zinnat medication is no exception. Thus, patients taking this drug should be aware that against this background, they may develop pseudomembranous colitis.
As therapeutic practice shows, during the treatment of Lyme disease with antibiotics in patients, a Yarish-Herxheimer reaction can be noted. According to experts, it is a certain consequence of the bactericidal effect of the drug on the causative agent of the disease - spirochete Borrelia burgdorferi. So that the patient does not spontaneously stop taking the medication, the doctor must explain to him that this is a fairly common and frequent consequence of treating Lyme disease with antibiotic agents. After a certain period of time, it passes on its own.
If the Zinnat drug was prescribed to patients with a diagnosis of diabetes mellitus, it should be borne in mind that sucrose is included in the suspension. In this case, it is recommended to replace the mentioned form of the drug with another. For example, tablets or powder intended for the preparation of a solution for intravenous or intramuscular injection can be used.
In the event that a drug in the form of a suspension was prescribed for a small child or teenager to treat a disease, you should be aware that it must be prepared using warm rather than hot liquid.
Interaction with other medical devices
Is it possible to take Zinnat medicine with other drugs at the same time? In most cases, yes. But there are several factors to consider. For example, the simultaneous administration of the drug cefuroxime and a medication such as Probenecid can lead to an increase in the AUC of the former by 50%.
It should also be noted that with the simultaneous use of an antibiotic and antacids, the bioavailability of the former decreases. But this only applies to the drug in the form of a suspension.
Price and analogues of an antibiotic
How much does the Zinnat drug cost? The price of this tool in different pharmacy chains may vary. However, the average cost of a medication in tablets is about 400 Russian rubles (for 10 pieces). As for the suspension, then for 50 ml of the drug you need to give about 350 rubles. A similar price is set for powder for injection.
What to do if, for one reason or another, the patient was unable to purchase the Zinnat drug? Its analogues are always sold in pharmacy chains. If you do not know what these drugs are, then we will list them right now.
So, the following drugs are analogues of the Zinnat remedy for the active substance:
- "Super."
- Aksetin.
- Cefurus.
- "Axosef."
- "Cefuroxime axetil."
- "Antibioksim."
- "Cefuroxime sodium."
- "Acenoveris".
- "Cefuroxime Kabi."
- "Zinacef."
- "Cefuroxime."
- Zinoksimor.
- "Cefurosin."
- Ketocef.
- "Cefurabol."
- Kefstar.
- "Cefroxim J".
- Xorim.
- "Tsetil Lupine."
- Proxim.
It can not be said that all the drugs mentioned have different forms of release. In this regard, they can be used both for adults and adolescents and young children.
Shelf life of the drug and its storage conditions
The shelf life of the Zinnat tablets is 2 years from the date of production, and the suspension and powder for injection are 12 months. But this is only on condition that the storage of the drug was carried out exclusively at room temperature. By the way, it is advisable to place the already prepared suspension in a refrigerator. Keep it in this form should be no more than ten days. After the specified time, the use of the drug is strictly prohibited.