Quite often, doctors prescribe their patients the drug “ACC” (“ACC”) for coughing. Instructions for the use of this tool, as well as its contraindications, indications and side effects, will be presented in this article. In addition, we will tell you about the form in which the mentioned medicine is released, what patients say about it, how much it costs and so on.
Packaging of the drug, its release form, composition
Do you know in what form the medicine “ACC” (“ACC”) for cough is released? Instructions for use inform us that this drug is produced in two different forms. Let's consider them in more detail:
- Medication “ACC” - powder (granular), intended for the length of the preparation of the solution. Such a medicine should be taken only by mouth. One 3 gram sachet of powder may contain 200, 100, or 600 mg of acetylcysteine. In a cardboard pack is 10, 6 or 20 bags.
- The drug "ACC" - effervescent tablets. In aluminum or cardboard tubes can be 20, 10, 100 or 50 pieces. One tablet contains 600, 200 or 100 mg of acetylcysteine. As for the auxiliary components, they include citric anhydride, sodium bicarbonate, ascorbic acid, mannitol, lactose anhydride, sodium citrate, blackberry flavor and saccharin.
Pharmacological action of the drug
What is the remedy “ACC” (“ACC”) for coughing? Instructions for use claims that it is a mucolytic drug. Due to the fact that the structure of the acetylcysteine molecule contains sulfhydryl groups, this causes the disulfide bonds of mucopolysaccharides of (acidic) sputum to break. As a result of such exposure, the patient visibly decreases mucus viscosity.
The drug in question has a mucolytic effect, and also facilitates sputum discharge due to a direct effect on its rheological properties. This tool remains active even in the presence of purulent mucus.
The medicine "ACC", the instruction of which is presented below, is very often used for prophylactic purposes. In this case, there is a decrease in the severity and frequency of exacerbations in patients with cystic fibrosis and chronic bronchitis.
Pharmacokinetics of the drug
What are the pharmacokinetic properties of the drug "ACC"? The instruction does not contain such information. This is due to the fact that pharmacokinetic studies of this medication have not been conducted.
The drug "ACC": indications
The drug in question is prescribed for the following deviations:
- acute and chronic sinusitis;
- diseases of the respiratory system, which are accompanied by the formation of difficult to separate and viscous sputum (for example, with bronchiectasis, acute and chronic bronchitis, cystic fibrosis, obstructive bronchitis, pneumonia, bronchial asthma and bronchiolitis);
- otitis media.
Contraindications
In the presence of any deviations, in no case should the “ACC” medication (powder and effervescent tablets) be prescribed? Contraindications to the use of this tool are the following conditions:
- blood spitting;
- an ulcer of the duodenum and stomach (especially in the acute phase);
- pulmonary bleeding;
- pregnancy period;
- hypersensitivity to the drug;
- period of breastfeeding.
It should also be noted that this medication is prescribed with extreme caution to patients with dilatation of the veins (varicose) of the esophagus, diseases of the adrenal glands, renal and / or liver failure.
Mode of application
How should I take ACC for cough? Instructions for use contain the following instructions on this subject. Adolescents and adults are prescribed 200 mg three times a day. For children from 6 to 14 years old, the medicine must be taken 100 mg three times a day. For babies from 2 to 5 years, the medication is prescribed 1 tablet (100 mg) twice a day. With such a deviation as cystic fibrosis, a child over 6 years old is given 2 tablets of the drug (100 mg) three times a day. As for babies from 2 to 6 years old, they should take a medicine of 100 mg four times a day.
Patients with a body weight of more than 30 kg with cystic fibrosis can increase the dosage to 800 mg per day.
With colds of short duration, the duration of therapy with the medication presented is 5-7 days. With cystic fibrosis and chronic bronchitis, the drug must be used for a longer time (for the prevention of infections).
How should I take the medicine "ACC 200"? The instruction says that this drug should be used only after eating (in order to avoid a negative effect on the gastric mucosa). It should be especially noted that an additional intake of fluid enhances the mucolytic effect of the drug.
Before use, effervescent tablets must be dissolved in half a glass of plain water. Ready solution should be used immediately. In exceptional cases, it can be left for 2 hours.
Overdose
With a deliberate or erroneous overdose of the drug, the patient has signs such as vomiting, stomach pain, diarrhea, heartburn, and nausea. Until today, no serious and life-threatening side effects have been observed.
Drug interaction
What will happen if you simultaneously take any medications and the ACC? Experts say that combination treatment can cause a number of undesirable reactions. Let's consider them a bit further.
With the simultaneous use of acetylcysteine and other antitussive agents, mucus congestion hazardous to health may occur (due to suppression of the cough reflex).
During the simultaneous administration of nitroglycerin and acetylcysteine, there is a chance of enhancing the vasodilating effect of the former.
Synergism of acetylcysteine with the simultaneous use of bronchodilators is noted.
Acetylcysteine is able to reduce the absorption of penicillins, cephalosporins and tetracycline. In this regard, they must be taken orally 2 hours after taking the first.
Acetylcysteine is not compatible with antibiotics such as Penicillin, Erythromycin, Cephalosporin, Tetracycline and Amphotericin, as well as proteolytic enzymes.
Upon contact of acetylcysteine with rubber and metal, sulfides are formed, which have a characteristic odor.
special instructions
With obstructive bronchitis and bronchial asthma, the drug in question should be prescribed with extreme caution. In this case, systematic monitoring of bronchial patency is required.
If, after taking the medication, the patient develops side effects, then it is necessary to stop taking the drug and immediately consult a doctor.
When dissolving any form of medicine, it is recommended to use glassware. In this case, contact with rubber, metals, oxygen and easily oxidized elements must be avoided.
When treating patients with diabetes, it should be borne in mind that 1 effervescent tablet corresponds to 0.006 XE.
To date, there is no information about the negative effect of the drug (in recommended dosages) on the ability to drive a car, as well as perform other activities that require special attention.
Shelf life and storage methods
The drug in question should be stored only in a dry place inaccessible to small children. At the same time, the air temperature should not be higher than 25 ° . The shelf life of the drug is three years. After this time, the use of medication is prohibited.
After taking an effervescent tablet, the plastic or aluminum tube must be tightly closed.
Price and analogues of the drug
The price of the “ACC” tablet can be different, depending on the pharmacy network, as well as on the margin for the goods. However, on average, such a medicine costs about 75-150 Russian rubles. The price of granular powder is similar to effervescent tablets.
What can replace the tool in question? In pharmacy chains, there are a huge number of analogues of the drug, as well as drugs with a similar effect (expectorant, mucolytic). Among the most popular, I would like to single out the following medicines: "Atsestin", "Acetylcysteine", "Vicks Asset ExpectoMed", "Mukobene", "Mukomist", "Mukoneks", "N-AC-Ratiopharm", "Fluimucil", "Exomyuk 200" , "Atsestad", "Lazolvan", "Ambrobene", "Ambroxol", "Mukosol", "Bronkatar", "Solvin", "Bromhexin", "Gedelix", "Mukaltin", "Prospan", "Stoptussin", " Ascoril "," Linkas "and others.
Testimonials of patients about a medical device
Now you know what “ACC” analogues are and what its price is. Tablets and powder for the preparation of the solution quite effectively cope with the task. This is the opinion most patients adhere to. The drug quickly treats acute and chronic sinusitis, as well as other respiratory diseases . Thanks to him, viscous and difficult to separate sputum easily moves away from the bronchi, significantly improving the condition of a sick person.
It is impossible not to note the fact that the tool in question has not only high efficiency, but also a relatively inexpensive cost. This fact is very pleasing to patients who cannot afford to buy expensive medications.