This article will discuss how to take Phosphogliv. It is a drug that helps restore liver cells and eliminates the causes of organ damage. However, this is not the only property of this drug. Below we consider its composition and indications, as well as the method of application and patient reviews.
The composition of "Phosphogliv"
The product is produced in Russia by the pharmaceutical company Pharmstandard. The drug is dispensed in pharmacies by prescription. The drug includes two active components at once. There are various forms of medication, including lyophilisate for the preparation of a solution for intramuscular and intravenous administration. This is confirmed by the instructions for use with Phosphogliv.
Lyophilization is a method of drying substances, which without exposure to high temperatures makes it possible to preserve the biological activity and structure of the active components.
The composition of Phosphogliv includes the following substances:
- Phospholipids of the lipoid C100. They are the main components of cell membranes.
- Trisodium salt of glycyrrhizic acid. It has antioxidant and anti-inflammatory effects.
- Maltose (refers to excipients).
The lyophilisate looks like a white or yellowish powder. Packed in bottles of 5 pieces in one package. The shelf life of the drug is two years.
The properties
According to the instructions for use, "Phosphogliv" has a complex effect, consisting in the following properties:
- Stabilization of intracellular and cell membranes. If they are damaged, then the active components of the drug restore and protect the cells.
- Phosphogliv acts as a hepatoprotector. It normalizes the metabolism of proteins and lipids, and also restores the liver, stopping the growth of connective tissue. Cells when taking the drug are protected from enzyme deficiency. The risk of developing cirrhosis and liver fibrosis is reduced.
- It has an antiviral effect on the liver. Active components relieve inflammation and stimulate the synthesis of interferons and phagocytes, increasing their effectiveness.
- With liver damage of a non-infectious nature, the drug reduces the severity of allergic reactions.
- Unlike analogues, Phosphogliv has a combined effect.
Indications and restrictions for admission
According to the instructions for use, Phosphogliv shows its effectiveness in the treatment of liver diseases, such as:
- Hepatitis of viral origin. The inflammatory process in the glandular tissue of the liver can have serious consequences for human health and lead to complete organ dysfunction.
- Hepatosis. Its other name is fatty degeneration of the liver. This disease leads to a violation of metabolic processes in the liver cells. The main prerequisite for the development of hepatosis is excessive consumption of fatty foods.
- Intoxication with alcohol or drugs that occurs when toxic substances enter the body.
- Cirrhosis. This is an irreversible process of replacing hepatic glandular connective tissue. The organ with this disease loses part of its capabilities and properties. Cirrhosis is a complication of alcohol dependence or hepatitis.
- Psoriasis. This is a dermatological disease, but one of the reasons for its development may be a pathological process in the liver.
- Neurodermatitis and eczema. These are diseases of an allergic origin. The drug neutralizes the negative effects of allergens and toxins. Thus, it is possible to achieve positive dynamics in treatment in a short time.
Indications "Phosphogliv" should be strictly observed.
Contraindications
There are a number of contraindications that limit or prohibit the use of the drug. Among them:
- Individual reaction to the active components of the drug.
- Gestational and lactational periods.
- Children under 12 years old.
The decision to prescribe Fosfogliv tablets to pregnant women and children can be made by a doctor, taking into account all possible risks and consequences. However, it should be borne in mind that no studies have been conducted on this issue.
Under the categorical ban is the simultaneous administration of the drug and alcohol-containing drinks. Ethanol reduces the effect of the drug, and with alcohol abuse can aggravate the patient's condition. Even drinks with a low ethanol content should be excluded. What else can you learn from the instructions for use with Phosphogliv?
Preventive use
The tool is not always prescribed in cases of exacerbated course of the disease or in its chronic form. Quite often, the drug is prescribed for preventive purposes in the following conditions:
- Stress.
- Unbalanced diet and frequent overeating.
- Low physical activity.
- Adverse environmental conditions.
- Alcohol abuse.
- Taking various drugs that negatively affect the liver.
Phosphogliv tablets are able to eliminate bloating and weakness in the abdomen, soreness and discomfort. Moreover, it has an effect in a short time.
It should be remembered that even for preventive purposes it is necessary to consult a doctor before taking the drug. The active components of the drug are rapidly absorbed in the small intestine, after first entering the bloodstream, and reach the liver. The peak concentration of the drug occurs six hours after use. The complete elimination of Phosphogliv occurs two days later.
Instruction manual
The lyophilisate is dissolved in water for injection at the rate of 2.5 g per 10 ml, the solution must be prepared immediately before use. The drug is administered slowly intramuscularly or intravenously. For droppers "Phosphogliv" is not used. The powder is forbidden to mix with other drugs or dilute with saline.
With an exacerbated form of the disease, injections are made 1-2 times a day. The duration of treatment is up to a month. If the pathology takes a chronic form, then therapy can be extended up to 6 months, and sometimes up to a year. In the future, injections can be replaced by a tablet form of the drug. Capsules "Phosphogliv" are taken two pieces three times a day, one month in case of exacerbation and six months with a chronic form of pathology.
Side effects
It is a relatively safe drug. Specialists note very rare side effects. The most common adverse reaction to intravenous administration of the drug is an allergy, accompanied by the appearance of urticaria. However, it passes as soon as the drug is no longer used. This is confirmed by reviews of Phosphogliv.
If the dosages prescribed by the doctor are exceeded, an overdose is possible, which is manifested by the following symptoms:
- Swelling.
- High blood pressure.
- Hypokalemia, in which the level of ions in the blood decreases sharply.
To eliminate the above conditions, the dosage of the drug is reduced or spironolactone is prescribed, which is a diuretic that does not affect the level of potassium in the body.
"Phosphogliv" does not adversely affect a person's psychomotor reactions. Therefore, against the background of his admission, it is allowed to perform work requiring attention concentration and drive a car.
Analogs of Phosphogliv
There are no similar solutions for injection, but there are quite a few similar drugs:
- Heptor. It is also available in the form of a lyophilisate. The active ingredient is ademethionine. It has not only the effect of hepatoprotector, but also has a psychotropic effect.
- Heptral. Similar to “Heptor” in composition and application.
- "Laennec." Acts as a hepatoprotector and immunomodulator. As part of a human placenta hydrolyzate .
- "Remaxol". It is made on the basis of succinic acid, methionine, meglumine, nicotinamide and riboxin. It is an inexpensive analogue of Phosphogliv.
- Gepa-Merz. It is produced in the form of a concentrate for the preparation of a solution. The main component is ornithine.
Injection solutions are most often used during exacerbations. For preventive purposes and as maintenance therapy, capsules are used.
Reviews
There are many reviews of Phosphogliv. I must say that opinions on the drug differ. He did not help some patients; others caused an allergic reaction.
However, there are much more positive comments about the drug. Many people use Phosphogliv for a long period of time, and it helps maintain liver function. At the same time, the state of health and general well-being improves markedly.
There is much debate about the effectiveness of hepatoprotectors in the treatment of liver pathologies. Many are of the opinion that such drugs are good only for prevention, not treatment. Many even healthy people regularly use Phosphogliv as a preventative measure and feel good.
However, you can not self-medicate and take drugs prescribed independently. Both doctors and people who are faced with the consequences of such independence are cautioning against this. You should not rely solely on reviews in search of the drugs you need, because each organism has its own characteristics that must be considered before taking Phosphogliv.