Runny nose is an unpleasant and annoying symptom. Shortness of breath causes discomfort and lack of oxygen, and the constant use of handkerchiefs contributes to the redness and flaking of the nostrils. In such cases, specialists can prescribe the Avamis nasal spray, the instructions for use of which will be discussed in detail in this article.
What is this remedy? What are its positive and negative properties? How to use the drug to treat the common cold? We will try to find answers to these questions.
In addition to the instructions for use, we will also familiarize ourselves with the reviews on the Avamis nasal spray, as well as with its analogues or substitutes.
A little bit about the composition
Composition - this is one of the first things that people pay attention to when studying the annotation for a drug. What does “Avamis” spray consist of, according to the instructions for use? The active substance is micronized hormone fluticasone furate. In one dose of the drug, there are 27.5 micrograms of active ingredient.
Other so-called excipients are also present. First of all, it is anhydrous dextrose (or glucose), polysorbate 80, dispersible cellulose, disodium edetate, benzalkonium chloride solution, purified water.
How is the product
Although some, faced with colds of the nasopharynx, prefer to be treated orally, that is, using tablets, the instructions for use with Avamis say that this drug is a nasal spray. That is, it must be applied intranasally.
Is Avamis a nasal drop? Instructions for use with this tool explain that the active substance is released as a spray, so they should not be instilled with a nose. The drug is sprayed (or sprayed) directly into the nostril. However, we will talk about this later.
“Avamis” is a white homogeneous suspension. Comes in a glass bottle protected by a plastic case. The kit also includes a dispenser in the form of a button and a nozzle as a sprayer of the solution itself. The volume of vials is designed for thirty, sixty and one hundred and twenty doses.
In what cases can doctors prescribe this drug?
What diseases are used
Most often, doctors prescribe the drug for allergic rhinitis (especially seasonal type), as well as for other ailments accompanied by nasal congestion and shortness of breath. For example, it may be sinusitis or an increase in adenoids.
What happens when an active ingredient enters the human body?
How does the drug work?
Although the main active ingredient of the drug is a hormone that has an anti-inflammatory effect, getting into the body, it does not provoke the production of hormones of its own. Its task is to influence the receptors of the nasal mucosa in order to lower their response to penetrating foreign substances. Thus, the protective function of the body against irritants decreases, since in a particular case it is not necessary, it only provokes unnecessary painful symptoms.
Absorbing into the blood, fluticasone furoate combines to interact with plasma proteins, after which not only the allergic reaction of the whole organism is inhibited, but also the vessels are narrowed, swelling subsides, and the runny nose stops.
Drug withdrawal
Rapidly entering the bloodstream, the hormone is almost immediately eliminated from the body with the help of the liver. Only one percent of the substance is processed by the kidneys, so the drug does not come out through the urine, but through the feces (intestines).
How to take the drug in order to achieve the most effective result?
General usage tips
Before injecting the medicine, make sure that the spray device is not broken. To do this, shake the drug for eight to ten seconds, then remove the cap-cap and press the spray button while holding the bottle in an upright position. Sometimes it will be necessary to press several times before a steam cloud of medication appears.
So, we found out that the device is working. What's next? Immediately before use, it is necessary to clean the nasal passages (blow your nose), shake the bottle well again and carefully insert the spray nozzle into one nostril.
Be careful! It is recommended to hold the glass bottle vertically, and direct the tip of the nozzle to the outside (i.e. to the ear), and not to the inside or towards the nasal septum. This orientation will ensure the best distribution of the drug. The head should be held upright, in no case throwing it back.
When you press the button, you need to take a breath in order to improve the distribution of the drug throughout the nasal passage. As soon as the injection has been made, it is necessary to remove the nebulizer from the nostril and exhale. If necessary, repeat the manipulation or inject into another nasal passage.
Once the drug has been used, it must be closed to prevent foreign substances (including moisture or dust) from entering the vial.
Be careful! When spraying, it is important to avoid contact with eyes. If this still happened, immediately rinse your eyes with running water.
Drug schedule
The first and most important - the tool should be used strictly according to the instructions, preferably at the same time of the day. Do not rush to abandon it without feeling the instant effect, since the drug begins to act after six, or even eight hours after administration. But how to apply the spray depending on the age of the patient? What does the annotation say?
First, let's discuss how the remedy is taken in treating small patients. According to the instructions for use, Avamis for children is prescribed one injection in each nasal passage once a day. This applies to children from two to twelve years old.
You can not use the medicine to treat babies up to two years. This is clearly recommended in the instructions for use "Avamisa" for children. According to reviews, this tool is not suitable for such babies and can cause serious complications and disturbances in the functioning of vital organs. For example, there is a danger of the spray entering the area of the ears, bronchi and even the digestive system. Moreover, taking a hormonal agent can provoke a hormonal imbalance in newborns and older children.
And what about the use of Avamis for adults? Instructions for use explain how the drug can be used to treat an adult. It is very important to follow the doctor’s prescription, as there are two treatment schedules for the spray. Firstly, it can be used one injection into each nostril twice a day. Or two injections into each nasal passage once a day. The optimal schedule and dosage, of course, is determined only by the doctor.
But how can Avamis be used in the fight against common diseases? This can be read below.
Allergic manifestations
How to use this tool to soften the body's reaction to irritating substances? In such cases, according to the instructions for use and reviews, Avamis should be used several weeks before a possible negative reaction, for example, fourteen days before the flowering of ragweed or the appearance of poplar fluff (these are the most common plants that cause seasonal allergies).
According to user reviews, many managed to overcome allergic manifestations or minimize their symptoms through the systematic use of hormonal drugs.
Common cold
Many experts do not recommend prescribing a drug for themselves, especially when it is not about allergic manifestations. However, in the annotation to the drug, general recommendations are written, according to which you can understand how to use this tool when spraying in the nose. Instructions for use “Avamisa” recommends using the product in accordance with the age indicator in combination with other treatment (antiviral or antibiotics). The drug does not cure a common cold on its own, it can simply alleviate the symptoms, reducing the sensations of itching, sneezing and profuse snot excretion.
Sinusitis Complications
This disease is also impossible to cure using only Avamis. However, otorhinolaryngologists proved that a hormonal agent can relieve swelling, thereby freeing the nasal passages from purulent secretions and cleansing the nasal mucosa for the use of other drugs. That is, Avamis is best injected before using other sprays or drops prescribed by a doctor for the treatment of sinusitis.
Adenoid Complications
According to the instructions for use, “Avamis” with adenoids cannot cure the disease on its own. It only eliminates symptoms, making breathing easier and thereby improving the overall well-being of children.
Are there any contraindications for this hormone?
When not to use
The annotation to the drug lists specific categories of patients who are contraindicated in the use of the drug. First of all, these are future and nursing mothers, since the effect of the active substance of this drug on the child has not been fully studied.
It should also be borne in mind that if a person suffers from serious pathological diseases of the liver and kidneys, then he needs to use Avamis with caution.
Also, as mentioned above, the hormone is contraindicated in children under two years of age. People of advanced age can use a spray, since not a single case has been recorded so that the drug is not suitable for the patient precisely because of his age.
Analyzing the topic of contraindications, it is also worth mentioning the individual intolerance of the active substance, which can cause various allergic reactions. However, this situation is quite rare.
And most importantly, Avamis cannot be used for any damage to the nasopharyngeal mucosa, whether it be ulcers, scratches, wounds, punctures or other surgical interventions.
Does the drug have side effects?
What you need to know about the side effect
It is very important to know that in case of an overdose, Avamis will not cause any severe symptoms or manifestations. This is proved by laboratory tests, when within three days the dose of the hormone was increased by 24 times. It is noteworthy that this practically did not affect the general condition of people and their well-being.
However, the spray can cause unpleasant side effects associated with individual intolerance to the hormone or its prolonged use. What can these symptoms express?
The most common adverse reactions to fluticasone furoate are nosebleeds. The main reasons for their appearance is the prolonged use of the spray (more than six weeks). Most often, unpleasant symptoms occur in small patients.
The next frequent side effect is ulceration (or the formation of ulcers, micro-wounds) on the mucosa in the nasal cavity, as well as swelling of the nasal passages. Sometimes the lack of perception of the body is expressed in skin rash and urticaria, less often Quincke's edema or anaphylactic shock can be provoked.
Of course, as soon as you notice any deterioration or negative manifestations in your well-being, you must immediately stop using the drug and inform your doctor.
Are there any restrictions on the use of other drugs during the treatment with Avamis?
How interacts with various drugs
The nasal spray can not be used together with a ketanosole inhibitor and Ritonavir, since their joint use can enhance the effect of fluticasone furoate. This, in turn, can provoke undesirable allergic manifestations.
Shelf life
Many people wonder how long it is possible to store the spray after opening the bottle. According to the instructions, you can use an open product for two months. In this case, it is recommended to preserve the drug at a temperature of from fifteen to thirty degrees.
A closed vial can be stored for no longer than 36 months (or three years) from the date of manufacture indicated by the manufacturer on the package.
Other effective drugs
What are the analogues of Avamisa? Instructions for use of the nasal spray explain what is the active substance of the drug and what is its spectrum of action. What drugs are considered identical or similar?
For example, Nazonex. Its active ingredient is the hormone furoate mometasone in the form of micronized monohydrate. Available as a metered spray. Most often, the drug is prescribed for seasonal allergic manifestations, sinusitis (both acute and chronic), mild forms of rhinosinusitis, nasal polyposis.
How to take "Nazonex"? Otorhinolaryngologists for the treatment of adults prescribe two injections into the nasal passages once a day. If the effect does not occur, then twice a day. For the treatment of children from two to twelve years old, one injection in each nostril once a day will suffice.
“Flixonase” is another drug with a similar spectrum of action. Its active substance is the micronized hormone fluticasone propionate. Its anti-inflammatory effect is used in the treatment of hay fever (or hay fever) and allergic rhinitis (seasonal and year-round), which are accompanied by a sensation of pain in the sinuses, profuse lacrimation, shortness of breath, burning or itching in the nose.
According to the annotation to the drug, it is contraindicated for children under four years of age. Adults (from twelve years old) are prescribed two injections in each nasal passage once a day for fourteen days.
Then another two weeks spray is applied, however already on one injection once a day. For the treatment of small patients (age group from four to twelve years) - one injection in each nostril.
So, we briefly listed the funds that are analogues of Avamis. Instructions for use and expert advice regarding these drugs have also been indicated.
A bit about reviews
What do patients using Avamis say to treat allergies? In general, people are pleased with the effect of the drug, noting that it copes with allergic reactions. If you start using the drug a few weeks before contact with a possible irritant, then there are practically no negative symptoms.
Some patients also admit that they used the nasal spray during pregnancy, fleeing sinusitis and allergic rhinitis. However, as far as this is permissible in subjective cases, it is up to you to decide.
On the other hand, some note possible side effects of Avamis, accompanied by swelling of the nasopharynx and itching in the sinuses.
Many note that they used a hormonal drug to treat elderly parents. In such cases, the spray had only a positive effect, practically without causing side effects.
Very rarely, patients mention that “Avamis” was prescribed for sinusitis or other serious diseases. On the other hand, its use in the treatment of adenoids in infants helped to ease the well-being of young patients and reduce negative symptoms.
And finally
As you can see, “Avamis” is an effective remedy for allergies and sinusitis. However, due to the fact that the active substance of the drug is a synthetic hormone, the nasal spray should be used with extreme caution. Above, we discussed in detail in what cases and doses a remedy is prescribed. You should know that it can not be used to treat babies up to two years. Under special supervision and supervision of a doctor, treatment with “Avamis” of pregnant women should be carried out. In this case, you need to be very careful about the drug, given its negative properties.
As you can see, it is best if the remedy is prescribed by a competent doctor who will carefully and objectively evaluate the benefits and harms of its use. The specialist also recommends an individual schedule of administration and the correct dosage of the drug, suitable only for you and your situation. Remember that self-medication is very unsafe. This is warned by the instructions for use of the Avamis nasal spray, as well as numerous reviews by medical professionals and patients about this drug.