The medicine “Cipralex” is an antidepressant. The drug inhibits the reuptake of serotonin, which provokes an increased concentration in the synaptic cleft of this neurotransmitter, increasing and increasing the duration of its effect on postsynaptic receptor regions. The active substance is escitalopram. The absorption of the product does not depend on the use of food. The bioavailability of the active ingredient is about 80%. After repeated administration, the average achievement of the highest concentration is about four hours. The metabolism process takes place in the liver cells. Most are excreted in the form of breakdown products through the kidneys.
Indications for taking Cipralex
The drug is recommended for depressive episodes of varying severity, panic disorders without or with agoraphobia.
Dosing schedule
The medicine “Cipralex” recommends taking it once a day, regardless of food. Against the background of depressive episodes, the medicine is usually prescribed at ten milligrams per day. In accordance with the tolerance of the patient, the amount of the drug can be increased to 20 mg / day. Two to four weeks after the start of therapy, a persistent antidepressant effect develops.
The Cipralex tool (the instructions for use confirms this) is recommended to be taken for another six months after eliminating the manifestations of the pathological condition in order to consolidate the achieved effect. In panic disorders without and with agoraphobia, treatment is started with 5 mg / day. Subsequently, the amount of drug is increased to 10 mg / day. Taking into account individual tolerance, the dosage can be increased to twenty milligrams per day. The medication reaches the highest therapeutic effect by about the third month of treatment.
Tablets "Cipralex". Adverse reactions
During therapy, nausea, anorexia, dry mouth, constipation or diarrhea, insomnia, hallucinations, and irritability may occur. The medication can provoke motor disorders, serotonin syndrome, convulsive seizures, excessive sweating, mania, anxiety, and hyperthermia. Orthostatic hypotension occurs on the basis of therapy , hyponatremia, galactorrhea, myalgia, depersonalization, agitation are likely. In some cases, impotence, decreased libido, anorgasmia, ejaculation disorder, anaphylactic reactions are noted. The medicine causes urinary retention, angioedema, purpura, sinusitis, rash, itching of the skin, arthralgia. Against the background of a sharp cessation of therapy with Cipralex (the instructions for use warns about this), dizziness, nausea, and headache are likely. As a rule, these reactions are slightly expressed and are of a short nature. Usually undesirable effects develop during the first two weeks of treatment, gradually disappearing with continued medication.
Contraindications
The tool "Cipralex" instructions for use does not allow for appointment during pregnancy, in combination with MAO inhibitors, with hypersensitivity. Do not prescribe it to patients under 15 years of age. Contraindications include lactation.