In this article, we consider the instructions for use and reviews for the Ginepriston preparation. What is this drug? Having a baby is a wonderful event when it is desired and planned. If pregnancy was not planned, but contraceptives were still failed, then the drug “Ginepriston” can help.
It is a means of emergency contraception, therefore it is advisable to use it only in case of urgent need.
Reviews about "Ginepristone" are abundant.
The composition and form of the drug
One tablet of the drug contains 0.01 g of the active substance mifepristone. As excipients, microcellulose, sodium carboxymethyl starch and calcium stearate are contained.
The drug is sold in pharmacies in the form of cylindrical tablets of light yellow color, weighing 10 mg each. One or two tablets are placed in a blister strip packaging or a plastic jar, which is packed in a pack of cardboard.
Reviews of gynecologists about Ginepriston will also be presented.
The mechanism of action of the drug
The drug is a synthetic steroidal antigestagen agent, that is, it blocks the action of progesterone at the receptor level.
Taking the drug causes an increase in the contractility of the myometrium, stimulates the release of substances that increase its sensitivity to hormones of a certain type. The effect of the drug is determined by the phase of the menstrual cycle in which it was taken. Depending on this, the medication causes inhibition of ovulation, a change in the endometrium or does not allow an already fertilized egg to gain a foothold.
What else does the Ginepristone manual tell us? According to reviews, it is very detailed.
Pharmacokinetics
After an hour and a half after the drug is taken, the highest concentration of the active substance is observed in the blood. Withdrawal in the first 3 days is very slow, then the process is noticeably accelerated, and after another 18 hours the drug is completely eliminated from the body.
Indications for use
"Ginepriston" is used as a means of emergency (postcoital) contraception. It is necessary to take the drug in a short time (no more than 72 hours) after sexual contact or in the event that the contraceptive used is unreliable.
According to reviews, "Ginepriston" for abortion is very effective.
Contraindications
This drug in some cases is contraindicated for use, among them:
- high sensitivity to mifepristone;
- adrenal insufficiency or prolonged treatment with glucocorticosteroids;
- any form of renal and liver failure;
- extragenital pathology in severe form.
Also, it should be taken with caution in diseases such as:
- various disorders of hemostasis, including those associated with previous treatment with anticoagulants;
- chronic obstructive pulmonary disease;
- severe arterial hypertension;
- diseases associated with cardiac arrhythmias;
- acute and chronic heart failure.
Side effects
According to reviews, "Ginepriston" can lead to various adverse reactions. Among them - a feeling of discomfort and pain in the lower abdomen, headache, weakness, dizziness, vomiting, nausea, blood from the vagina, menstrual irregularities, fever, urticaria.
Method of use and dosage of the drug
It is required to take 1 tablet orally for a maximum of 72 hours after unprotected intimacy. You should refrain from eating 2 hours before and after taking the medication.
You can use this drug, regardless of the phase of the menstrual cycle, this does not affect the effectiveness of the drug. This is confirmed by the reviews of doctors about "Ginepristone."
Overdose
Signs of an overdose occur when taking a dose of more than 2 g. In this case, the likelihood of unwanted adverse reactions increases. Also, in the case of taking a large dose of "Ginepriston", adrenal glands may malfunction, up to the development of adrenal insufficiency.
Symptomatic therapy is prescribed to treat side effects.
Taking the drug simultaneously with non-steroidal anti-inflammatory drugs is contraindicated, since NSAIDs significantly reduce effectiveness.
Alcohol interaction
Ginepriston, like most drugs, is not recommended for use with alcohol. Alcoholic beverages not only enhance undesirable side reactions, but also significantly reduce the effectiveness of the drug. At least five hours should elapse between drinking any alcoholic beverage and taking the drug.
Special instructions for use
"Ginepriston", as a means of emergency contraception, is undesirable for use as a means of planned, ongoing protection against pregnancy. Also, this drug is not used to prevent infection with sexually transmitted diseases, including HIV and AIDS.
It is considered safe to take the drug for emergency termination of pregnancy no more than 2 times a year. This frequency of use does not cause serious complicated reactions, in contrast to the regular intake of these tablets or other similar drugs.
Use during pregnancy and lactation
It is contraindicated to take "Ginepriston" while carrying a child. If you need to take the drug during breastfeeding, then after this you need to take a break in breastfeeding for two weeks.
Sold by prescription.
Analogs
Allocate the following drugs acting on an organism similarly to "Ginepriston":
- Ginestril;
- "Zhenale";
- "Esmiya";
- Miropriston;
- "Mifegin";
- Mifepristone
- Mifeprex;
- Pencrofton;
- "Mytholian";
- Mifotab;
- Farmateks;
- "Postinor";
- Escapel.
"Ginepriston" has a milder effect on the female body than, for example, "Postinor" or "Escapel", while not only not inferior to them in effectiveness, but often surpasses them. It also causes very few side effects, therefore it is recommended by gynecologists as a safer tool. At the same time, it is convenient to use - you need to take one tablet at once, and not two with an interval of several hours.
Next, consider the opinions of Ginepriston.
Reviews of gynecologists
According to doctors, "Ginepriston" is an effective and safe means of emergency contraception. The effectiveness of the drug with strict adherence to the instructions for use is more than 90%. However, experts categorically do not recommend the use of this tool on an ongoing basis, since this increases the risk of adverse effects. Instead, gynecologists advise carefully selecting reliable means of protection against unwanted pregnancy and genital infections.
Reviews about "Ginepreston" from patients
Most of the women who used this drug were satisfied with the result of its action. Its effectiveness and relatively mild, in comparison with other similar means, action are noted. At the same time, many patients complained of the occurrence of such adverse reactions as a lost menstrual cycle, pain in the lower abdomen, spotting from the genital tract, dizziness, and weakness. Many recommend this remedy as a last resort, while at the same time paying attention that reliable planned contraception is much safer than emergency.
conclusions
"Ginepriston" is a synthetic steroid emergency contraceptive used for termination of pregnancy in the first three days after unprotected intimacy. The drug is not suitable for routine contraception and is not able to protect against STDs, but its use is justified if the constantly used protection at some point was not reliable enough.
This tool can be taken, regardless of the phase of the menstrual cycle, but there are certain recommendations for use, non-compliance with which significantly reduces the effectiveness of the drug. So, you need to take a pill in the first 72 hours after intercourse, without mixing the drug with food, alcohol and NSAIDs.
Ginepriston has a number of side effects and contraindications, so you must carefully read the instructions before use.
Although this drug is considered one of the most effective and safe among emergency contraceptives, it does not give a 100% guarantee of termination of pregnancy, therefore it is recommended to use correctly selected means of planned contraception without resorting to extreme measures.
We reviewed the reviews of Ginepristone and the consequences of its use.