"Dioxidin" is an antibacterial drug that is part of the quinoxaline group. Often used in a variety of medical fields. In the article, we consider the instructions for use for the drug "Dioxidin" in ampoules.
The drug is available in the form of a solution that can be used for external and internal use. The concentration of the solution is 1%; it is packaged in ampoules made of transparent glass and having a volume of 10 ml. Additionally, the ampoules are packed in a cardboard box. Each box has instructions from the manufacturer. The solution is sterile, may have a greenish or yellowish tint.
Structure
According to the instructions for “Dioxidine” in ampoules, the main active component of the solution is hydroxymethylquinoxalindioxide. Each ampoule contains 100 mg of the active ingredient. The auxiliary substance is injection water.
Indications for use
As indicated by the instructions for "Dioxidine" in ampoules, the solution can be prescribed to patients for preventive and therapeutic purposes. Suitable for use in the following cases:
- Wound surfaces that have a purulent character and provoked by polio.
- Processing phlegmon that infects soft tissue.
- Burns of varying severity, accompanied by the attachment of a bacterial infection.
- Trophic ulcers that do not heal for a long period.
- Wound surfaces having different depth and severity of the course.
- The processes of inflammation of an infectious nature, provoked by the activity of pathogenic microflora. However, the drug is recommended to be used only in cases where other chemotherapeutic and antibiotic agents are ineffective.
For injections, “Dioxidine” is used if the patient has the following pathologies:
- Complicated rhinitis, sinusitis, sinusitis and other pathological changes in the nasal cavity.
- Complicated otitis media.
- Inflammatory processes of a purulent nature, affecting organs located in the chest and abdominal cavities - postoperative wounds, phlegmon, mastitis, cystitis, lung abscess, peritonitis.
Contraindications
According to the instructions, “Dioxidine” in ampoules should be used exclusively on the recommendation of a specialist. It is important to carefully study the proposed instructions before starting a therapeutic course, since there are situations in which the use of the drug is strictly contraindicated. It is forbidden to use the medication if the patient has the following physiological or pathological conditions:
- Severe renal dysfunction, acute renal failure.
- Inadequate adrenal cortex activity.
- The lactation period.
- Pregnancy.
- Individual susceptibility to any of the components of the product.
Using
Most often, "Dioxidine" is prescribed to patients who are in hospital. The drug is used internally and externally in various medical fields.
If you want to enter "Dioxidin" intravenously, the contents of the ampoule must first be diluted with sterile saline to the desired concentration. The treatment regimen, its duration and the recommended dosage are determined by the doctor individually, taking into account the clinical symptoms and nature of the disease.
If therapy is supposed to be for long healing or suppurating wounds, lotions with a solution must be used. You should take a sterile cloth from gauze, moisten it with the drug and attach to the affected area. If the wound is deep, it is tightly tamped with gauze turundas dipped in Dioxidine. If there is a drainage system, it is shown several times a day to pour 100 ml into the wound cavity. In this case, “Dioxidin” acts as an antiseptic.
When treating wounds provoked by osteomyelitis, it is shown to wash the wound surface with a 1.5% solution of the drug, after which a gauze cloth moistened with a solution of 1% concentration is applied to it.
As the instructions for Dioxidin in ampoules inform us, the solution can be used as a prophylactic in case of the likelihood of complications after surgery. To this end, it is necessary to treat the wound surface every day. If the patient does not have individual intolerance, the solution can be used for up to 2 months.
According to the instructions for use, Dioxidin in ampoules for the nose can also be used.
If the patient has a process of inflammation localized in the nasal cavity, for example, sinusitis, sinusitis, frontal sinusitis, it is indicated to rinse the nasal cavity with a solution. For convenience, you can use a syringe without a needle. Such washing is indicated twice a day. The drug is effective in the treatment of complicated sinusitis in cases where other medicines do not help. Rinse punctured maxillary sinuses should be carried out up to 3 times during the day. After rinsing, gauze turundas moistened in the preparation are placed in the nasal cavity.
According to the instructions for use, "Dioxidine" in ampoules for inhalation can also be used.
The procedure is as follows:
- Dilute the medicine with saline (1: 4 at a concentration of 1% and 1: 2 at a concentration of 0.5%).
- Initially, the process should take no more than 2-3 minutes. Subsequently, it is extended to 5-7 minutes.
- With a runny nose and nasal congestion, inhalation is carried out through the nose. With angina, cough and sore throat, the procedure occurs through the mouth.
- You can not drink and eat food for an hour after the completion of the procedure.
- Inhalations are carried out once a day for 6-7 days.
About whether it is possible to carry out inhalation with a drug such as "Dioxidine" to a child, you should definitely check with your pediatrician. Most often, such therapy is not recommended under the age of 2 years.
"Dioxidine" in ampoules for the nose of a child according to the instructions can be used only after a full examination.
The medication can be prescribed to patients as an independent tool for the treatment of purulent otitis media, accompanied by the spread of pathology to the Eustachian tube, and as an element of complex treatment. With otitis media, patients undergoing inpatient therapy wash the ear cavity with a solution, and then insert gauze from the gauze into the ear.
Intracavitary administration
If intracavitary administration of the drug is required, then the solution is injected into the cavity using a catheter or drainage tube. The volume of solution used depends on the volume of the cavity in which the pathological process is localized. For administration, a solution with a concentration of 1% is used, and its administration is carried out once a day.
The duration of the therapeutic course is determined by the doctor individually. If the patient has good tolerance to the drug, then its use is allowed for up to 2 months.
This is confirmed by the instructions for use with "Dioxidine" in ampoules. For children, the drug can be used only after consulting a doctor. The instructions indicate that it can only be used by patients over 18 years of age. However, Komarovsky believes that the remedy can be used for colds, bronchitis and some other diseases, if the attending physician considers it necessary.
Use of the drug in the lactation period, during pregnancy
It is strictly forbidden to use it during pregnancy. When conducting special studies, it was found that the active substance "Dioxidine" can have teratogenic and mutagenic effects on the fetus. In addition, the solution is quite toxic to the embryo, its use can provoke the appearance of abnormalities and congenital malformations.
The use of "Dioxidine" in the lactation period is also contraindicated, since the active component can be excreted together with breast milk and subsequently enter the child's body. If there is an urgent need for the use of the drug, the woman must first stop breastfeeding.
Negative impact
When using "Dioxidine" the following negative phenomena may develop:
- External use can provoke allergic manifestations in the form of swelling, rash, dryness, tightness, burning of the skin. This is stated in the instructions for "Dioxidine" in ampoules. Use it carefully for the nose.
- Intracavitary, intravenous use can cause convulsions, general weakness, headaches, chills.
Severe intoxication may be accompanied by anaphylaxis and the occurrence of angioedema.
With the development of adverse reactions, the patient must abandon the use of the drug and consult a doctor. A dose adjustment or drug replacement is likely to be required.
Overdose
Intravenous or intracavitary administration of the drug over a long period of time can cause an overdose, expressed in impaired activity of important organs and kidney function. Intoxication therapy is symptomatic, since the specific antidote is unknown.
Analogs
If necessary, "Dioxidin" can be replaced with drugs whose mechanism of action is similar. The most popular analogues of the drug are Trinefron, Ofloxin, Gatifloxacin.
Before replacing Dioxidin with another drug, the patient should consult a doctor, since not all of these drugs have the same therapeutic activity. Moreover, each of them has its own set of contraindications and is able to provoke specific negative effects.
It is important to remember that Dioxidine therapy can only be administered as directed by a specialist.