How to take "Pirantel" for adults? We will understand in this article.
Thousands of people are exposed to helminths annually, therefore modern pharmacology has to constantly develop new medications for helminthic infestations. Nevertheless, time-tested drugs continue to lead, among which can be noted Pirantel. For several decades, this medical product has been trusted by both patients and doctors.
Description
The drug is low toxic and can be used in anthelmintic therapy even in children from six months. However, taking medicines against helminths is always associated with a certain risk, therefore, a doctor should prescribe the drug for babies. Reviews about the "Pirantel" are abundant.
Release form
The tool refers to synthetic medicines. The main drug component of this drug is pyrantel pamoate. It is available in the form of tablets and suspensions (syrups). Auxiliary components may vary depending on the dosage form of the drug.
The tablets are packaged in cartons of six or three pieces. The suspension is represented by a yellow liquid in glass bottles with a volume of 15 milliliters.
Structure
Pirantel tablets from worms contain 250 mg of the main substance. Dosage is not divided into adult and child. The tablet form of the medication is prescribed, as a rule, to adults and adolescents, since treatment is limited to a single use of the drug.
Young children can not swallow tablets, so for them you need to purchase the drug in the form of a suspension that can be given to the child separately or added to the drink - juice, compote or tea.
pharmachologic effect
“Pyrantel” is an anthelmintic drug that can cause neuromuscular blockade of helminths sensitive to it. Actively given medication in relation to the following types of parasites:
- Enterobius vermicularis;
- Necator americanus;
- Ancylostoma duodenale;
- Trichocephalus trichiurus.
Affects sexually mature and immature helminths. The mechanism of action of this drug is based on the main property of the active substance to block the activity of the nervous and muscle systems of worms in the developmental phase and adult nematodes. After taking the medicine, parasites lose their ability to move and fix on the internal walls of the intestine, as a result of which they are naturally excreted from the body with feces. This pharmacological effect deprives the drug of anthelmintic properties against larvae and migratory helminths, therefore, for absolute disposal of them, therapy should be carried out in two courses. Used "Pirantel" and for prevention.
Pharmacokinetics and pharmacodynamics
The main substance is practically not absorbed through the walls of the intestine. Since it is unable to penetrate the blood, its systemic effect is extremely low. This is favorable in terms of minimal risks of side effects, however, it is bad for the treatment of helminths migrating throughout the human body.
The highest concentration of the drug is achieved 1-3 hours after taking the pill or suspension. Substances that enter the blood in small quantities undergo a metabolic process in the liver. The drug is removed from the body, mainly through the intestines.
"Pyrantel" from worms can be considered one of the least toxic drugs that are used in clinical medicine to eliminate worms. The tool is effective against helminthic infestations caused by pinworms, hookworms, roundworms and a number of other intestinal worms belonging to the class of round. Depending on the type of parasite, the dosage of this agent varies, and therefore it is necessary to carefully study the instructions for its use.
Indications for use
Pyrantel tablets are prescribed to patients who suffer from the following pathologies:
- ascariasis;
- enterobiosis;
- necatorosis;
- hookworm infection.
You can take "Pirantel" for prevention.
It must be remembered that self-medication of helminthic infestations can be hazardous to health, therefore, in order to choose the right medical tool, determine the dosage and treatment regimen, it is necessary to identify the type of parasite. For this purpose, you should contact a medical institution and conduct appropriate laboratory diagnostics.
Contraindications
The drug practically does not have a general systemic effect on the body, however, it has a number of certain limitations in use. The drug "Pirantel" is not prescribed during the treatment of myasthenia gravis, as well as in patients with severe forms of liver failure. This drug in tablets can be prescribed only from the age of three, and in the form of a suspension - from the age of six months.
Since it is possible to develop allergic reactions to the active components of the drug, it is not recommended to take it to people who are highly sensitive to such substances. With caution, it should be used during pregnancy. As for the treatment with the drug during lactation, the feeding of the child should be interrupted for the period of therapy.
Adverse reactions
Since the Pirantel medicinal product exerts its effect mainly on the intestines, adverse reactions occur to the greatest extent in this digestive organ. According to the reviews of Pirantel, the patient may experience symptoms such as nausea, diarrhea, bloating, cramping, vomiting, etc. Skin allergies, itching, and rashes are possible with the development of an allergy to the elements of the drug.
Overdose
If the dosages of this medication are exceeded, disorders of the nervous system can occur, which are expressed, as a rule, by dizziness, hallucinations, confusion, and some other signs. Special symptomatic medicines used in case of an overdose of Pirantel have not been developed, therefore, in case of extremely severe conditions, the patient needs to wash the stomach.
Fields of application
Pirantel tablets are most often taken once. Dosage should be calculated based on the weight of the patient. Special preparation for anthelmintic treatment, as well as compliance with the rules of dietary nutrition is not required.
If a severe nematode lesion is observed, and the patient's weight exceeds 75 kilograms, the specialist, as a rule, adjusts the dosage of the drug upwards, dividing the dose by two or three times. So, the medication regimen, depending on the type of disease:
- Pinworms are worms, the most difficult to diagnose, however, the pathologies caused by these helminths respond well to drug therapy. Worms are small in size, and their life cycle runs exclusively in the intestinal cavity. Therapy of enterobiosis occurs through a single dose of the drug "Pirantel", calculated by the weight of the patient. After three days, you should pass an analysis for the presence of worms, which is subsequently repeated after another three days. If the expected effect of treatment is absent, then the patient is recommended to take the medicine again in the same dosage or the specialist replaces it with another medication.
- Ascarids require oxygen, and their larvae mature outside the intestinal cavity. As a result, adult individuals of this type of helminth living in the intestine and nematodes migrating throughout the body may be present in the patient at the same time. In this regard, therapy with the Pirantel drug is carried out twice, as a rule, with a break of two weeks.
- Hookworms, which parasitize mainly in the duodenum, are much more difficult to cure. The course of therapy with Pirantel medication is carried out for three days, and the total dosage of the drug is increased. To treat children for hookworm infection, the doctor may recommend another medical tool that has a less toxic effect.
Let’s figure out how to take “Pirantel” for adults.
Method of using tablets and suspensions
The medicine is allowed to be taken at any time of the day, regardless of the meal, however, treatment is recommended in the morning. Before applying the suspension, the vial is shaken for the best distribution of drug components. If the taste of the suspension is unpleasant for a child, it can be added to a sweet drink. That is, in the morning or in the evening, “Pirantel” to drink does not matter.
In cases of pinworm and roundworm lesions, the drug in suspension recommends taking 15 ml once. For children from six months of age, the dosage should be calculated on the basis of 2.5 milliliters of Pyrantel suspension per ten kilograms of body weight.
Ankylostomidosis is treated in 2-3 doses of the drug, that is, the treatment is extended for the corresponding number of days. In this case, a single dose per day is doubled. For children, it is 5 ml per ten kilograms of weight, adolescents are prescribed 30 ml of a Pirantel suspension.
The tablets of the drug are very large, which is why, when swallowed, there are certain difficulties. They should either be chewed or pre-crushed. It is better to take the medication during breakfast or in front of him, drinking plenty of fluids.
Dosages of tablets are:
- from three to six years - one tablet;
- up to 12 years - two tablets;
- from 12 years old and adults - three tablets;
- for people whose body weight exceeds 75 kg, four tablets.
How to take Pirantel during pregnancy?
This medication for the treatment of helminthic invasion is prohibited for use in the first trimester of pregnancy. In other cases, it is necessary to obtain the permission of a specialist who determines the dosage regimen and dosage, taking into account the type of disease and the risk to the fetus.
"Pyrantel" during pregnancy can be toxic.
During lactation, the drug can be taken subject to a temporary cessation of the lactation process. In this case, the child should be transferred to a mixture for artificial feeding. Since the concentration of active substances when taking the medication reaches maximum concentrations within 3 hours, after this time, breast milk can be decanted and poured, and the next portion can be given to the child.
special instructions
If the patient lives together with other family members, then Pirantel is recommended to be taken by all relatives at the same time to avoid re-infection.
People whose activities are associated with a high concentration of attention, as well as those who drive a car, should be careful, because the effect of the medication may be weakness, drowsiness, and dizziness.
After the release of helminths from the intestine, the likelihood of re-infection increases, so all members of the family are advised to carefully consider personal hygiene.
Concomitant use of this medication and alcoholic beverages increases the risk of toxic effects on the body.
Reviews of "Pirantel"
The opinion of specialists and patients about this medicine is very mixed. Many of them consider this drug to be the most effective and safe in the treatment of worms, while others, on the contrary, prefer to choose more modern medicines.
Positive reviews suggest that Pirantel is very well tolerated by both adults and children, practically does not cause side effects and effectively destroys the most common types of helminths. Based on this, doctors often prescribe it to children.
Negative reviews about the treatment with Pirantel reflect information that this drug is very difficult to take due to the large size of the tablets. This is especially true for those patients who experience discomfort when chewing tablets. In addition, some individuals experienced unpleasant symptoms associated with taking the drug, which were expressed in disorders of the stool, skin rashes and nausea.
We reviewed the reviews of the Pirantel.