Is a medicine such as Desal effective? Reviews about the drug are presented at the end of the article. It also describes detailed instructions for the use of this drug, its composition, pharmacological properties, release form, etc.
Form, composition, packaging and description of the medicinal product
You can buy the medication in the following forms:
- Oral preparation "Desal" (tablets). Reviews of experts report that they are blue in color, round and biconvex. The active element of this preparation is desloratadine. As for the additional ingredients, they include magnesium stearate, microcrystalline cellulose mannitol, talc, pregelatinized corn starch. This drug goes on sale in cell packages packaged in cardboard boxes.
- Suspension "Desal" (syrup). The tablets are for adult patients, and the syrup is for children. The active substance of this form of the drug is also desloratadine. In addition, it includes auxiliary components in the form of sorbitol, propylene glycol, sodium citrate dihydrate, citric acid monohydrate, hypromellose, sucralose, disodium edetate and Tutti-Frutti flavoring. The clear liquid has no color. The medicine is free from foreign particles and is available in dark glass bottles (a measuring spoon is included in the kit).
The principle of action of the drug
How does Desal medicine affect the human body? Instructions for use (the prices of tablets and syrup will be indicated later) reports that this is an antihistamine that has a long-lasting effect.
The drug in question refers to histamine H1 receptor (peripheral) blockers.
According to experts, desloratadine is the primary metabolite of loratadine. This substance is able to inhibit reactions that are allergic in nature, as well as release pro-inflammatory chemokines and cytokines.
The antiallergic agent “Desal” (reviews about the drug are ambiguous) facilitates the course of allergies and prevents its development. In addition, the medication in question has an antiexudative and antipruritic effect. It reduces the permeability of blood vessels and capillaries, prevents spasms of smooth muscles and prevents the development of swelling.
How does the Desal medication (tablets) affect the human central nervous system? Instructions for use, reviews of experts report that this drug has no effect on the nervous system, and also never causes drowsiness.
It should be noted that the active substance of this drug does not affect the attention and psychomotor reaction of a person.
The therapeutic effect of Desal appears half an hour after its administration and lasts about a day.
Pharmacokinetic properties of the drug
Where is the Desal medication absorbed? Reviews of the drug say that its active component is absorbed from the digestive tract. In the blood, it is observed after 30 minutes, and its highest concentration is noticeable after three hours.
Binding to plasma proteins is 86-88%, and the half-life is approximately 27 hours. The removal of desloratadine from the human body is carried out through the intestines and together with urine.
Indications
What helps the medicine "Desal"? Instructions for use (the prices of this remedy are not very high) reports that this drug is prescribed to eliminate the symptoms of allergic reactions and alleviate the patient's condition. Indications include:
- allergic rhinitis (itching of the palate, rhinorrhea, nasal congestion, sneezing, itching of the eyes, redness of the eyes, lacrimation, itching in the nose);
- urticaria (skin itching and rash on the skin).
Contraindications
Under what conditions is it not recommended to take Desal? Reviews about the drug report that it should never be used during pregnancy. Also, it is not used in children under 12 years of age (only in tablet form) and during breastfeeding.
This medication is not prescribed for patients with hypersensitivity to the active or any auxiliary ingredient.
With caution, Desal tablets and syrup are recommended for people with severe renal failure.
How to use the medicine "Desal"?
The use, composition, reviews about this medication are presented in this article.
Antiallergic pills and syrup should be prescribed only by an allergist. Reactions such as itching, urticaria, rash, etc., in adult patients and children are treated according to a similar pattern.
Both forms of the drug in question are prescribed only inside. Taking the medication does not depend on eating. Its dosage is determined by the doctor. Usually it is 5 mg per day.
Side effects after taking
“I drink“ Desal ”from an allergy, and the condition only worsens ...” - these are the reviews that some patients leave about this medication. Experts emphasize that this drug really has many side effects. Consider the most common of them:
- fatigue, dry mouth, regular headaches;
- vomiting, diarrhea, abdominal pain, dyspepsia, nausea;
- drowsiness, dizziness, psychomotor hyperactivity, insomnia;
- an increase in the concentration of bilirubin, hepatitis, an increase in the activity of liver enzymes;
- palpitations, tachycardia;
- myalgia.
Also, while taking an antiallergic drug, people may experience mental disorders, hallucinations, itching, allergic reactions, anaphylaxis, rash, angioedema, urticaria.
Overdose cases
Take the drug “Desal” at the dosages recommended by the allergist, despite the fact that even with a significant excess of doses (for example, 9 times), the patient does not have any deviations. Although the development of drowsiness is possible.
For treatment purposes, after an overdose, it is necessary to rinse the victim's stomach and give him activated charcoal.
Through hemodialysis, desloratadine is not excreted from the human body.
Drug interaction
The medication in question does not affect the intake of other drugs. Also, other drugs do not affect its therapeutic properties. In addition, desloratadine is not able to enhance the effect of ethanol on the central nervous system.
Special recommendations for taking antiallergic drugs
Patients with severe renal impairment "Desal" is prescribed with extreme caution.
This medication does not have any effect on a person's ability to drive vehicles. Although at the same time it should be borne in mind that in some people it can cause drowsiness.
Price and analogues
How much does the desal anti-allergic agent cost? Reviews about the drug, the price will be presented right now. You can buy this medicine in a pharmacy for 210-370 rubles (depending on its form of release, the number of tablets and the amount of syrup).
You can replace this drug with drugs such as Desloratadine Canon, Ezlor, Lordestine, Nalorius, Blogir-3, Desloratadine-Teva, Desloratadine, Erius, Desloratadine-Pharmaplant "," Elisha ".
Patient Reviews
You can get a lot of information about the drug by reading the reviews. About antiallergic agent "Actavis Desal" comments leave a lot of patients. Among them, you can find both negative and positive ratings. Most people report that this drug effectively and fairly quickly eliminates all the symptoms that are inherent in allergic reactions.
According to satisfied patients, after taking a syrup or tablets, the patient's well-being improves markedly. In addition, the use of this drug is very convenient. To achieve the maximum therapeutic effect, it is enough to take it once a day.
As for the negative messages, most of them talk about the manifestation of many side effects.