"Polydex" is a drug with antimicrobial and anti-inflammatory components. The medication is used externally for the treatment of infectious and inflammatory pathological processes of ENT organs.
The drug is made in the form of a spray and drops. The second dosage form is a colorless solution of a light yellow hue. Polydex contains several main active ingredients:
- Dexamethasone sodium metasulfobenzoate.
- Polymyxin B Sulfate.
- Neomycin.
In addition, the structure of the drops includes additional substances, which include:
- caustic soda;
- lemon acid;
- ethylene glycol polymer;
- thiomersal;
- ethoxylated sorbitans;
- water.
Pharmacological properties
According to the instructions for use, nasal drops are considered a combined drug, the therapeutic effect of which is due to the main active components included in its composition:
- Neomycin has the maximum pharmacological effect against bacteria such as staphylococci, Escherichia coli, Klebsiella pneumonia, hemophilic bacillus.
- Polymyxin B has a bactericidal effect on gram-negative bacteria.
- Dexamethasone lowers the severity of the inflammatory process by suppressing the activity of immunity.
According to the instructions and reviews for "Polydex", nose drops have an extensive spectrum of action against a huge number of different types of bacteria.
Indications
The use of drops of "Polydex" is indicated for infectious and inflammatory pathologies:
- Purulent rhinitis (a consequence of improper or insufficient treatment of acute rhinitis).
- Sinusitis (an infectious and inflammatory disease of the sinuses that are inside the upper jaw, on both sides of it).
- Sinusitis (inflammation of the mucous membrane of the sinuses).
- Frontitis (inflammation of the frontal sinus, a type of sinusitis, more complex inflammation of several sinuses).
- Acute and chronic rhinopharyngitis (acute, chronic inflammation that appears on the mucous membrane of the nasal passages and posterior pharyngeal wall).
- Otitis (otorhinolaryngological disease, which is characterized by inflammatory lesions in the ear).
- Chronic adenoiditis (acute or chronic damage to the pharyngeal tonsil of the lymphopharyngeal ring).
Contraindications
According to the instructions for use and reviews of "Polydex", ear drops and nose drops are prohibited in certain conditions of the body, which include:
- Hypersensitivity to neomycin.
- Traumatic or infectious disorders of the thin, impermeable to air and liquid membrane that separates the outer and middle ear.
- Viral infectious lesions of the middle ear (herpes virus or herpes zoster), in which the use of dexamethasone, which is part of the structure of the medication, can cause additional activation of pathogens.
- Angle-closure glaucoma (a pathological process that leads to injury to the optic nerve).
- Kidney and liver disease.
- Albuminuria (a pathological phenomenon, which indicates the appearance in the urine of a protein, mainly serum albumin and a much smaller amount of serum globulin).
- The patient's age is less than 2.5 years.
According to reviews, drops of "Polydex" in the ear and nose should be used with extreme caution if people have signs:
- Hyperthyroidism (a chronic disease characterized by an increase in the hormonal activity of the thyroid gland and excessive production of hormones).
- Pregnancy
- Hypertension (a chronic disease characterized by a prolonged persistent increase in blood pressure).
- Angina pectoris (pain in the heart due to insufficient blood supply to the heart muscle).
- Coronary heart disease (organic and functional damage to the muscles of the heart, which is characterized by a lack of myocardial microcirculation).
- The period of breastfeeding.
How to take the medicine
According to the instructions for use and reviews for drops of "Polydex", children and adults are prescribed to drip in the ear from 1 to 5 drops twice a day for ten days.
Before use, you need to hold the bottle in your hand a little. After instillation, the head should be kept tilted for several minutes to better get the solution into the ear.
According to the instructions and reviews for the drops of "Polydex" for the nose, children from twelve years old need to irrigate the nasal passages no more than three times a day. Therapy lasts from five to ten days.
It must be held vertically, with the head slightly tilted forward. If within ten days there is no improvement, you need to see a doctor and stop the drug therapy.
It is not recommended to use the medication to rinse the sinuses. Reviews about the "Polydex" (ear drops and nose) confirm that the positive properties of the use of the drug depend on the individual characteristics of the patient's body.
Adverse reactions
In general, Polydex drops are well tolerated by patients. Sometimes local allergic reactions may occur in the area of using the medicine in the form of rashes and itching of the skin. Instillation in case of a disturbed eardrum can lead to toxic damage to the middle and inner ear.
If side effects occur, therapy should be discontinued and consult a doctor. Sometimes the appearance of resistance of pathogenic microorganisms to the active components of the drug is possible, which requires its cancellation and the selection of another antimicrobial agent.
What other negative effects can the drug cause?
According to reviews, drops of Polydex with phenylephrine for the nose in rare situations can provoke a feeling of dryness in the nostrils, as well as certain side effects:
- Nettle rash (a disease whose main sign is the occurrence of blisters on the skin).
- Tremor (fast, as well as rhythmic movements of the legs, arms or body, which are provoked by muscle cramps and are associated with a temporary delay in afferent signals).
- Migraine (neurological disease, which is characterized by frequent episodic or constant severe pain).
- Tachycardia (increased heart rate more than ninety beats per minute).
- Pallor of the skin.
- High blood pressure.
- Insomnia (sleep disturbance, which is characterized by superficial as well as intermittent sleep, a delay in its onset or premature awakening).
Features
Before starting therapy with Polydex drops, you need to thoroughly familiarize yourself with the instructions for the medicine. There are several important points to consider:
- Before starting treatment, you need to make sure that there is no damage to the integrity of the eardrum.
- It is not recommended to instill drops of "Polydex" in conjunction with other medicines for external use.
- The solution can be instilled strictly only in the external auditory meatus, it can not be administered under pressure or taken orally.
- If the inflammatory process does not go away after ten days of therapy from the start of therapy, then you need to see a doctor.
- Perhaps the use of the drug "Polydex" for pregnant and lactating women only for strict medical reasons.
- Dexamethasone is considered one of the active components of the drug, it can give the wrong result when determining the presence of stimulating chemical compounds in athletes (doping control).
- The drug does not directly affect the functioning of the central nervous system, as well as the speed of psychomotor reactions and the ability to concentrate. Therefore, you can drive a car during treatment with this drug.
- In pharmacies, drops of "Polydex" are dispensed according to a doctor's prescription. You can not use them yourself without medical prescription.
- Due to the small degree of absorption of the active components of the drops into the general bloodstream, there were no signs of drug poisoning.
Substitutes
According to reviews, drops of "Polydex" have a number of generics:
- Sofradex
- Maxitrol.
- Neladex.
- Isofra.
- Nazarel.
- Otipaks.
- "Nazofan."
- "Flixonase."
- "Rinofluimucil."
Before replacing the original Polydex product with an analogue, it is recommended that you consult a doctor to rule out contraindications.
"Polydex" or "Isofra", which is more effective
What kind of remedy is considered the most optimal for children and adults, only a doctor can tell in each specific situation. As part of Isofra, framycetin sulfate is an antibacterial substance that belongs to the same group as the active component of Polydex. To accurately determine how effective one of the drugs is, it is necessary to conduct bacteriosis in order to obtain complete information about the sensitivity of pathogens to each of the antibiotics.
In addition, it should be noted that Isofra contains only one active substance - framecithin sulfate, and several in the Polydex structure, therefore, the second drug has a combined effect, it can not only eliminate bacteria, but also participate in elimination all unpleasant signs of respiratory diseases.
Rinofluimucil or Polydex
The first medication, unlike the second one, contains acetylcysteine and tuaminoheptane, which have a vasoconstrictor, as well as anti-inflammatory and antioxidant effect. But Rinofluimucil, unlike Polydex, does not have an antibiotic in its structure.
According to the restrictions on the use of "Rinofluimucil" differs in that it is not recommended for use with thyrotoxicosis. Naturally, both medicines are prohibited with increased sensitivity to their existing or additional components.
Neither drug is recommended during pregnancy. Both drugs are prescribed with extreme caution under the supervision of a medical professional in a situation if the likely benefit is higher than the possible risks.
How to store the drug
According to the instructions for use, the shelf life of the Polydex medication is thirty-six months. The medicine can be stored in its original packaging, in a dark, as well as dry and inaccessible place for children at a temperature of no more than plus twenty-five degrees. The cost of "Polydex" varies from 260 to 320 rubles.
Opinions
Reviews of drops of "Polydex" confirm its increased effectiveness, since the drug is considered a new generation of medicine. It is noted that the drug in most cases improves the patient's condition after several applications.
In addition, drops will help reduce the pronounced intensity of pain in the maxillary sinuses, as well as migraines. But it should be remembered that during drug therapy it is necessary to strictly follow the instructions for use and use it only as recommended by a specialist.
In the reviews for Polydex ear drops for children, there are negative responses about the inconvenience of using the bottle. In their responses, patients indicate that the drug has a quick effect and exhibits increased effectiveness in the treatment of complicated rhinitis (runny nose), as well as bilateral sinusitis.
According to the opinions of medical specialists, nasal drops for children and adult patients are usually used in complex therapy due to their good compatibility with other drugs. Nevertheless, it is not combined with some medicines.
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