The drug "Lotseril" is an antifungal drug for topical use. It is used for the treatment of nail lesions (onychomycosis) caused by dermatophytes, mold and yeast, as well as for the prevention of damage to nail fungi.
The medicine "Lotseril", reviews of which are completely positive, is produced in the form of nail polish with a 5% content of amorolfine - the active active substance. The delivery set includes swabs for cleaning, spatulas and disposable nail files.
Pharmacokinetics of the drug "Lotseril"
Reviews of pharmacists describe the therapeutic effect of the drug. The active substance from the varnish enters the nail plate, and then in the nail bed, where it stops the reproduction of fungi, causing their destruction. The therapeutic concentration of the drug is stored in the affected organ for a week, with prolonged use, the medicine does not accumulate in the body.
Amorolfin slows down the production of enzymes involved in the biosynthesis of fungal cells, reduces ergosterol, and destroys the structure of fungal cells. Depending on the concentration, the drug has a fungistatic or fungicidal effect.
Indications for the use of the drug "Lotseril"
Doctors' reviews recommend using the medicine to treat nail diseases caused by fungi in cases of damage to more than two-thirds of the nail plate. The medication is also prescribed for preventive purposes.
Dosage and administration of the drug "Lotseril"
Patient reviews indicate that varnish should be applied to the nails twice a week. Before the first use of the product, the affected areas of the nail should be removed as much as possible, using files for this. Then the nail surface must be degreased and treated with swabs moistened with alcohol. At the next use of varnish, the affected nails are again removed with a file that cannot be reused. The medicine "Lotseril" is applied to the surface of the nail with a spatula. Before processing the next finger, the spatula must be dipped in varnish, it is forbidden to wipe off excess funds on the neck of the bottle. After the procedure, the nails should dry for three to five minutes.
Drug treatment is continued continuously until a new nail grows or the affected areas are completely cured. The duration of therapy depends on the site of infection and its severity. Usually, the standard course of treatment for fingernails lasts for six months; for fingernails, it takes nine months to a year.
Contraindications side effects of the drug "Lotseril"
Reviews of patients who used the tool indicate a slight burning sensation around the circumference of the nails after applying the varnish, which soon passes. This is caused by the action of the solvent. There are practically no contraindications. You should not use the drug for children, as well as for people with individual intolerance to the components of the drug.
Due to the lack of information on the effect of the drug on pregnant and lactating mothers, varnish is not recommended for use in this category of patients.
The drug "Lotseril": analogues
The drug according to the active substance has no structural analogues. Preparations similar in their anti-fungal effects are Anmarin, Binafin, Diflucan, Nizoral, Fungoterbin, Flucostat. The closest in form and treatment is the Batrafen medical device. Both “Loceryl” or “Batrafen” varnishes are effective for the prevention and treatment of nail mycosis. However, it should be remembered that varnishes will help if the area of damage does not exceed 80 percent of the nail plate.