The drug "Nystatin", reviews of which note the effectiveness of this drug, especially against Candida fungus, is a proven antifungal drug. It is low toxic. It is well tolerated by patients, rarely causes side effects, is effective, affordable.
Composition and form of release of the drug
The Nystatin remedy belongs to antibacterial antifungal drugs. In reviews of it, patients note that when using this medication, the appearance of side effects is possible, which manifests itself in the form of an upset gastrointestinal tract.
The drug "Nystatin" has several forms of release:
- Tablets.
- Vaginal suppositories.
- Rectal suppositories.
- Ointment.
For all forms of release, only one active substance is used - nystatin. Auxiliary components vary, depending on the form of release.
The tablets have a round shape and yellow saturated color. Produced in a dosage of 25,000 and 50,000 units (abbreviation means units of action). Packed in aluminum blisters of 10 pieces, as well as in glass and polymer cans of 20 and 100 pieces. Packed in cardboard boxes, which contains instructions for use.
About rectal and vaginal suppositories "Nystatin" reviews are favorable. They write that these drugs remove thrush in just a few uses. Suppositories are painted yellow and packaged in cell blisters of five pieces. The carton contains two such blisters.
Ointment, like other forms of release, has a yellow color. Packed in an aluminum tube with a volume of 15 or 25 ml.
Tablets are stored in a dry place, protected from the sun and children, at a temperature of 18 to 20 ° C. Suppositories and ointment should be kept at a temperature regime not exceeding + 5 ° C, preferably in the refrigerator.
The shelf life of tablets and suppositories is two years, and ointments - three years from the date of their manufacture. After the expiration date, the drug should not be used.
The drug is produced in Russia.
Pharmacology
In reviews of "Nystatin" it is noted that he quickly and successfully heals fungal diseases.
The medicine refers to antibiotics of the polyene series. It has a pronounced antifungal effect. It is active against yeast-like fungi such as Candida. Does not affect bacterial infection. The resistance of these fungi to the drug develops slowly. It has a fungistatic property.
The structural compounds of nystatin are dual, which provokes the appearance of tropism with the created cells of yeast-like fungi. The nystatin molecule with this interaction enters the membrane and creates its own channels for the movement of electrolytes in the inner part of the cells. An increase in osmolarity leads to the death of a cell damaged by the fungus. The cell itself is leased.
The medicine is practically not absorbed from the gastrointestinal apparatus. The main part of the medication, which is taken orally, is excreted in feces. Means "Nystatin" is not characterized by cumulative qualities.
Indications and contraindications
According to reviews of some patients, tablets, suppositories and Nystatin ointment in the advanced stage do not help from thrush. They note that the drug is effective only at the initial stage of development of a fungal infection. This remedy is also prescribed for candidiasis affecting the internal organs. The medicine is used to prevent the appearance of candidiasis, which often appears in patients who have used antibacterial drugs for a long time.
Reviews of candles "Nystatin", mostly positive. Patients note that they are indispensable for thrush (vaginal candidiasis). Vaginal suppositories are used not only for treatment, but also for the prevention of fungal complications that occur during the course of antibiotics.
Rectal suppositories are administered for candidiasis affecting the intestines and to prevent the appearance of a fungal infection in this organ.
Contraindications to the use of "Nystatin" are violations of the liver, pancreatitis, duodenal ulcer and stomach. Do not use the product during pregnancy and while breastfeeding. A ban on the use of the drug is excessive sensitivity to the substances that make up the drug.
Method of application, dosage
It is recommended to apply only the oral instructions to the Nystatin tablets. Reviews of patients note that the pills help completely remove candidiasis of any localization in two weeks of regular intake.
For adults, the drug is recommended to be used from 4 to 8 times a day, 500,000 units. If generalized candidiasis takes place , then the drug is prescribed in a dosage of 6,000,000 units / day.
In childhood (from one to three years), tablets are prescribed to drink 3-4 times a day for 250,000 units. At the age of three years and older, the drug should be taken 4 times a day for 250,000-500,000 units. The therapeutic course is two weeks. If necessary, then after seven days the treatment can be repeated.
Nystatin ointment is used in the treatment of candidiasis of the skin and mucous membranes. During treatment, the drug is applied in a thin layer on the damaged surface twice a day. Therapy lasts for 7-10 days. To achieve a better effect, the use of Nystatin tablets is added to the use of the ointment. This drug is also used in combination with other antifungal agents.
Treatment with vaginal suppositories is carried out twice a day. Suppositories are inserted into the vagina in the morning and evening after hygiene procedures. The duration of treatment is 14 days.
Reviews and instructions for the use of suppositories "Nystatin" rectally report that the drug should be used twice a day. They are introduced into the rectum for two weeks. If necessary, the treatment is repeated after a week.
The drug in the form of tablets or suppositories is used only as directed by a doctor.
Side effects
Reviews about the Nystatin tablets are mostly positive. They note that the drug is no less effective than modern means. Despite the effectiveness of the drug, in some cases, patients noted negative reactions of the body after taking the pills. Side effects occurred in the form of vomiting, nausea, diarrhea. People were worried about discomfort and abdominal pain. The activity of the gastrointestinal apparatus was disrupted.
During the use of Nystatin preparations, allergic reactions appeared, these are:
- Itching of the skin.
- Derma irritation.
- Hives.
In some cases, the patient's body temperature increased, a complication of the disease was observed against the background of the development of resistance to Candida fungi.
If negative symptoms occur, the use of tablets and other Nystatin preparations should be discontinued and consult your doctor to review treatment.
To date, no cases of overdose with this drug have been identified.
special instructions
When taking antibiotics, Nystatin protects against thrush. Reviews note that the tool prevents the risk of this disease. It should not be taken without a doctor's prescription, as there are contraindications and there is a likelihood of side effects.
If negative reactions of the body occurred during treatment with this drug, then you should consult a doctor, refuse to continue using the drug or reduce the dosage.
During menstrual bleeding, vaginal suppository therapy should not be interrupted. If there is a fungal disease of the vagina, then treatment should be carried out immediately in both sexual partners. During therapy, sexual contact should be avoided.
If the treatment is carried out by "Nystatin" and "Clotrimazole" at the same time, then the effectiveness of the second drug is reduced.
This is indicated in the instructions for the candles "Nystatin." In the reviews, patients note not only the effectiveness of this medication, but also its affordable price.
The cost of the drug, analogues
The drug "Nystatin" has several forms of release and is affordable. So, tablets in a dosage of 500,000 units, in the amount of one hundred pieces, cost between 100-120 rubles, 20 tablets can be purchased for 40 rubles. Ointment "Nystatin" in a volume of 15 ml costs about 60 rubles. The price of vaginal suppositories ranges from 50-70 rubles. Rectal suppositories (10 pieces) can be purchased for 50 rubles.
If for some reason the drug "Nystatin" did not fit, it can be replaced by the following analogues:
- Pimafucin. The active substance is natamycin. It treats candidiasis of the internal organs, skin and mucous membranes. It can be used in antibiotic treatment to prevent thrush. Vaginal candles cost around 500 rubles, for 6 pieces. The price of 20 tablets ranges from 400 rubles.
- "Ketoconazole." This is another antifungal drug that can replace Nystatin. It is used not only for candidiasis, but also for onychomycosis, seborrhea, histoplasmosis, paracoccidiomycosis and other fungal infections. The spectrum of its action is somewhat wider than that of Nystatin. The active substance is ketoconazole. Ten tablets can be purchased for 170-200 rubles, and ointment 15 g for 200-240 rubles.
- "Mikosist." It is made in the form of capsules and candles. Contains the active substance fluconazole. Effective for deep mycoses and systemic candidiasis. It can be used to prevent fungal infections. Seven capsules with a dosage of 50 ml can be purchased for 500 rubles, one capsule of 150 mg is within 300 rubles.
There are many other analogues that can become a worthy alternative to Nystatin. Most of them are more expensive.
Do not forget that the selection and replacement of the drug should only be done by a doctor. Otherwise, the treatment may not bring the long-awaited result and can cause negative reactions of the body.
Positive feedback from doctors
Candles and pills "Nystatin" reviews of doctors earned a variety of different. Those doctors who use the drug in their practice say that it is an old and proven remedy. As a rule, it is prescribed if, as a result of bacteriosis, the sensitivity of Candida fungi to nystatin was revealed.
Doctors often prescribe Nystatin suppositories for thrush. Reviews of experts note that for better effectiveness, they combine the use of suppositories with taking pills. Additionally, other drugs may be prescribed.
To prevent pathogenic fungal microflora from developing against the background of antimicrobial therapy, some doctors prescribe Nystatin thrush tablets with antibiotics.
Reviews of doctors warn that this drug must be taken for a long period. To avoid nausea, tablets should be drunk on a full stomach. It is not recommended to reduce the dose on their own, since a lower dosage can develop resistance in Candida fungi.
Negative opinion of doctors
Instructions for "Nystatin" and reviews of doctors warn that this tool can not be used without the appointment of a specialist. Some of them speak out about the drug is not quite benevolent. They claim that this is an old drug, you need to drink it for a long time, unlike modern medicines. Many consider this medicine rather weak. Doctors note that Nystatin tablets often cause diarrhea and nausea, as well as other negative reactions of the body. They believe that it is better to buy a medicine more expensive, but safer and more effective.
Some doctors, at the beginning of their practice, used Nystatin, but then, due to its low effectiveness, they were forced to abandon it.
Instructions for use of "Nystatin" and reviews of doctors describe in detail the contraindications for which this medicine should not be taken. In addition, doctors constantly warn that this drug can only be used as directed by a doctor.
What patients say
Instructions for use with Nystatin tablets and patient reviews report that they can cause negative reactions of the body. Patients are advised to use them only at the dosage prescribed by the doctor.
Many patients were satisfied with this drug. They believe that the drug acts quickly and effectively. These people treat them with candidiasis of the mucous membranes, skin, larynx and other organs. Some patients report that the medicine practically does not cause side effects. Nystatin may be used to treat oral candidiasis in children. In this case, a quarter of the tablets are ground into powder and placed on the tongue of the baby. Moms testify that candidiasis in the mouth passes in 2-3 days.
This drug is also used to treat thrush in women both in combination with other medicines, and as an independent drug. How effective is the drug in this area? In some, the result was on the second and third day after the use of tablets or suppositories. Others did not notice the action of this drug at all, so they had to choose another treatment. Some women note that vaginal suppositories are uncomfortable to use, as they leave marks on underwear. Therefore, many ladies refuse to treat vaginal suppositories in the morning and inject candles only at night.
Negative reviews indicate a low effectiveness of the drug. Patients indicate that it is unable to cope with the advanced stages of fungal infection and can cause serious bowel problems. After treatment with Nystatin, some patients had to restore the intestinal microflora for a long time.
Some ladies found the Nystatin tablets to be of non-standard use and successfully treated dandruff by adding medicine to hair masks and shampoo.
The drug "Nystatin" reviews deserved different. A lot of people are happy with the effect of the drug. As many patients refused to use it in favor of modern and more effective means.
What to choose for treatment, "Nystatin" or more modern analogues? The final decision in this matter remains with the doctor, who, based on diagnostic data, prescribes therapy.