Unfortunately, elevated cholesterol is a problem that many people face, especially in old age. The accumulation of this substance in the body leads to serious consequences, including disruption of the normal functioning of the cardiovascular system. In such cases, patients simply need lipid-lowering drugs.
Of course, the modern pharmaceutical market offers a huge selection of such drugs. Quite often, doctors recommend patients taking Ovenkor. Instructions for use here are quite simple, adverse reactions are rare, but the visible effect appears a few weeks after the start of therapy. So what is this tool? What properties does it have? Are there any contraindications? The answers to these questions will be of interest to many readers.
Composition and form of release
The drug "Ovenkor" - a medicine that is available in the form of round tablets with a solid film shell. The main active substance here is simvastatin. By the way, in a pharmacy you can buy a drug with a dosage of 10 or 20 mg of the active ingredient in each tablet.
Naturally, some auxiliary substances are also present in the composition. In particular, lactose, butyl hydroxyanisole, as well as citric acid, microcrystalline cellulose, castor oil, magnesium stearate, ascorbic acid, corn starch, talc, titanium dioxide, polyethylene glycol 4000, hydroxypropyl methylcellulose and pregelatinized starch are used in the production.
Pharmacological properties
"Ariescore" is a medicine that has several useful properties at once. Penetrating into the body, the active substance of the drug enters into metabolic reactions, during which the activity of the specific enzyme HMG-CoA reductase is inhibited. It is this substance that catalyzes the initial stages of cholesterol synthesis.
Thus, this drug reduces the level of triglycerides and low density lipoproteins in blood plasma, which, accordingly, reduces total cholesterol. Along with this, the drug increases the content of high density lipoproteins, which also positively affects the work of the body.
It is worth noting that really visible changes appear two weeks after the start of the drug. To achieve the maximum therapeutic effect, a treatment course of 4-6 weeks is required. As a rule, the effect of the drug ceases after discontinuation of the tablets - if the diet and other recommendations of the doctor are not followed, the cholesterol level gradually begins to return to the initial values.
The drug is adsorbed very quickly by the walls of the digestive tract. The maximum concentration of active substances in the blood is observed after 1-2.5 hours after taking the pill. The degree of communication with plasma proteins is 95%. The metabolism of the drug occurs in the tissues of the liver. The bulk of the metabolites are excreted from the body along with feces. About 10-15% comes out with urine.
The main indications for use
In which cases is it advisable to take Ovenkor? Indications for use - any violations that are associated with the accumulation and increase in cholesterol in the body. Quite often, doctors prescribe this medicine to patients with primary hypercholesterolemia, especially in cases where a proper diet, weight loss, physical activity and other activities do not have the expected effect. The course of therapy prevents the further development of coronary atherosclerosis.
Hypolipidemic drugs are also effective in combined forms of hypertriglyceridemia and hypercholesterolemia, which are not corrected by non-pharmacological methods.
In some cases, the medicine is prescribed to patients suffering from coronary heart disease. In particular, it is used to prevent myocardial infarction. The drug slows down the development of coronary arteriosclerosis, reduces the likelihood of risk during revascularization procedures, and also reduces the likelihood of developing cardiovascular disorders such as transient ischemic attacks and stroke.
The drug "Ariescore": instructions for use
Before starting therapy, the patient must undergo a complete medical examination. Only a doctor can correctly draw up a treatment regimen with the help of Ovenkor. Instructions for use contain only general recommendations.
As a rule, patients are recommended to take the drug once a day, preferably in the evening (for example, before bedtime). The adsorption rate does not depend on food intake, but the tablet needs to be washed down with plenty of water. The daily dose directly depends on the patient's condition and ranges from 10 to 80 mg of simvastatin. Dose changes (decrease or increase) should be carried out at intervals of four weeks. According to statistics, the maximum therapeutic effect in most cases is achieved when taking 20 mg of the drug per day. Throughout the treatment, the patient should follow a low cholesterol diet.
Are there any contraindications?
Many patients are interested in questions about whether all categories of patients can take Ovenkor. The instruction for use states that the medicine has a number of contraindications, which you should definitely familiarize yourself with. First of all, it is worth mentioning hypersensitivity to simvastine, statin drugs, as well as excipients that are present in tablets.
This medicine is not prescribed for patients suffering from porphyria, certain diseases of the skeletal muscles (for example, myopathy), as well as acute disorders in the liver, which are associated with an increase in enzyme activity. The drug is also not used to treat children and adolescents, pregnant women (there is evidence of negative effects on the fetus).
Relative contraindications include arterial hypotension, acute infections, endocrine disorders, metabolic disorders, and alcoholism. Also, the drug is not prescribed for patients who have recently suffered a serious injury, surgery or organ transplantation.
Possible side effects and complications
In some cases, therapy may be associated with some complications. In particular, sometimes patients complain of disorders of the digestive system, which are accompanied by severe nausea, vomiting, stool disorders, abdominal pain. Much less often, an increase in the activity of liver enzymes, the development of hepatitis, and inflammation of the pancreas are observed.
The drug can negatively affect the nervous system. In particular, treatment may be accompanied by disorders such as persistent headaches, blurred vision, impaired taste, and dizziness and insomnia. Much less common is the development of asthenic syndrome, peripheral neuropathy, as well as the appearance of parasthesia and muscle cramps.
May cause side effects from the musculoskeletal system. In some patients, the development of myopathies and myalgias is observed, less often - rhabdomyolysis. Allergic reactions are also possible, which are accompanied by a skin rash, itching, urticaria, swelling, shortness of breath, flushing, and flushing of the skin. Less commonly observed is an increase in sensitivity to light, the development of vasculitis, arthritis, angioedema. Other side effects include decreased potency, anemia, increased heart rate, and acute renal failure.
Overdose, its symptoms and treatment methods
In fact, cases of overdose are recorded extremely rarely and, as a rule, are accompanied by an exacerbation of side effects. If the drug was taken recently, it is advisable to induce vomiting, rinse the stomach and take the sorbent. The treatment in this case is symptomatic. It is extremely important in the first few days to monitor the work of the kidneys and liver. In the case of the development of renal failure (extremely rare) and other serious complications, hemodialysis is indicated.
Interaction with other drugs
Before starting treatment, be sure to tell your doctor about the medications you are currently taking. The combination of antifungal agents (for example, ketoconazole) with this drug increases the risk of myopathy. In the same way, Ovencor interacts with cytostatics, immunosuppressants, fibrates, and certain antibiotics. The concomitant use of Ovenkor with high doses of nicotinic acid is contraindicated. By the way, for the duration of therapy, doctors strongly recommend that you stop using grapefruit juice.
Are there any effective analogues?
Unfortunately, for one reason or another, this medicine is not suitable for all patients. Therefore, many are interested in whether it is possible to replace the Ovenkor drug with something. Analogs, of course, exist.
For example, such means as Vazilip, Zovatin, Zokor, Simvastatin are considered quite effective substitutes. Simgal, Simvor, and Holvasim possess the same pharmacological properties.
In any case, it should be understood that you can not arbitrarily stop taking the drug "Ariescore". Analogs can only be selected by the attending specialist. Self-medication can lead to unpleasant and even dangerous consequences.
Analogue of the drug "Simvastatin": instructions for use, price
This medicine is a direct analogue of "Avenor", as it contains the same active component. That is why many patients are interested in additional information about the medicine “Simvastatin”. Instructions for use, price, properties - all this, very important points.
The medicine is also available in tablet form and has almost the same composition. It has the same hypolipidemic properties, lowers blood cholesterol. The principle of application is the same - the daily dose is prescribed at one time, and depending on the patient’s state of health, it can be from 5 to 80 mg of simvastatin.
But the price of the drug is much less. For example, 30 tablets with a dosage of 10 mg will cost you 100 rubles, and Simvastatin 20 mg costs about 150-200 rubles (for the same number of tablets). Due to the low cost, many patients choose this drug.
How much is the medicine?
Many people are interested in additional information about the medicine Ariescor. Price, analogues, patient reviews - these are extremely important issues. Moreover, for many patients, the cost of a drug is a priority.
So how much will Ovenkor cost. The price, of course, depends on many factors. For example, it is worth taking into account the manufacturer, the dosage and number of tablets, as well as the price policy of the pharmacy, etc. For about 450-550 rubles, you can purchase a pack of 30 Ovenkor tablets (20 mg). The price for the same number of tablets, but with a dose of 10 mg, is slightly less - 350-400 rubles.
Reviews of patients and doctors about the medicine
Many people are looking for additional information about this medicine. What is Ariescore really? Reviews of doctors about the drug are mostly positive. Experts really note that this tool is well tolerated by patients. Moreover, it helps to quickly lower cholesterol and prevent the development of dangerous consequences.
What do patients themselves say about Ovenkor? Reviews of patients confirm that the medicine helps to cope with a host of problems, especially if combined with non-drug methods of treatment. Some patients develop side effects that disappear with a decrease in the daily dose. Perhaps the only drawback is the cost of the drug, since there are cheaper and more affordable analogues.