In the article, we will consider the reviews of doctors and patients about the antibiotic Wilprafen.
The drug is a broad-spectrum antibacterial drug belonging to the macrolide group. The main active ingredients of this medication have a detrimental effect on most known pathogenic microorganisms. Reviews about Wilprafen are abundant.
Composition and form of release
This pharmaceutical product is available in the form of tablets for oral administration - in carton packs are blisters of 10 pieces. Each tablet is coated with a white film and on one side has a special horizontal notch.
According to the instructions, the main active ingredient in Vilprafen is josamycin, the content of which in one tablet is 500 mg. In addition, in the production of this medication, some additional substances are used - macrogol, magnesium stearate, talc, microcrystalline cellulose, titanium dioxide, aluminum hydroxide.
Is Wilprafen a weak antibiotic? Let's figure it out.
Pharmacological effects
A medical device is prescribed for internal administration with a variety of bacterial infectious pathologies. The active substance of the drug actively affects the causative agents of inflammatory processes, inhibiting the production of synthesis by pathogenic bacteria. Josamycin is able to accumulate in the lesions, thereby the drug has a powerful bactericidal effect and is highly effective against gram-positive (streptococci, staphylococci, pneumococci) and gram-negative microorganisms (Helicobacter pylori), and some anaerobic (clostridia, peptococci, peptostocis). This tool has a detrimental effect on ureaplasma, chlamydia and can be used in the complex treatment of these pathologies in the field of venereology and gynecology.
Reviews about the antibiotic Wilprafen are mostly positive.
After oral administration of tablets, active active elements are rapidly absorbed through the mucous membranes of the digestive tract into the systemic circulation. The maximum concentration of josamycin in the blood is observed approximately two hours after taking the medication. The highest concentrations of this medicine can be observed in human biological fluids - sweat, vaginal discharge, saliva, sperm, bile, and lacrimal fluid.
Indications for use
This medication is prescribed to patients for therapeutic purposes for the treatment of the following pathological conditions:
- inflammatory infections occurring in the organs of the respiratory system: bronchitis, pneumonia, pharyngitis, tonsillitis, bronchopneumonia, tonsillitis, sinusitis, inflammation of the nasopharynx and larynx, paratonsillar abscesses (as part of complex treatment);
- inflammatory and infectious diseases processes of the oral cavity: gingivitis, periodontal disease, flux, prevention of inflammatory processes after tooth extraction or surgical removal of the cyst;
- inflammatory process of subcutaneous fat and skin: furunculosis, carbunculosis, acne, pyoderma, abscesses and abscesses, anthrax, erysipelas, lymphadenitis, lymphogranulomatosis;
- infectious and inflammatory processes in the organs of the genitourinary system: cystitis, pyelonephritis, urethritis, inflammation of the prostate in men, endometritis, adnexitis, inflammation of the cervix after unsuccessful gynecological procedures, septic abortions, prevention of bacterial infections after surgical interventions in the pelvic organs, as well as chlamydia, gonorrhea, uraeplasmosis.
The composition of the antibiotic "Vilprafen" and reviews about it are of interest to many.
Contraindications
The drug is contraindicated in patients with the following conditions:
- with individual intolerance to certain constituent elements of the drug;
- liver failure;
- the period of pregnancy and breastfeeding;
- history of severe allergic phenomena that occurred in the form of a reaction to antibacterial medications from the macrolide group.
Dosages of the drug and method of use
Tablets of the drug "Vilprafen" must be taken orally, without crushing and chewing, with a sufficient volume of water. This drug is usually prescribed for administration after meals or half an hour before it.
Dosages and duration of therapeutic treatment are selected by a specialist for each individual patient individually. This, as a rule, depends on the diagnosis, the severity of the infection process, the occurrence of complications, tolerance and sensitivity, age, body weight.
According to the instructions for this medication, the daily maximum dosage for adult patients and children after 14 years of age should be 1-2 g, and divide it into several doses. At the initial stages of the development of the inflammatory process, if there are no contraindications, adult patients are prescribed one tablet of the Vilprafen medication twice a day. The duration of such treatment for various diseases can vary, but the medicine should be drunk for at least five days. The maximum duration of treatment is no more than two weeks. In the absence of a positive effect and improvement of the patient's condition, he needs to consult a specialist in order to correct dosages, clarify the diagnosis and normalize treatment. Even if the patient felt better, the course of treatment with this antibiotic is not yet over. In this case, in no case should you stop taking the drug yourself, otherwise the inflammatory process may resume with greater force, and infectious agents will become resistant to josamycin. In this case, the doctor will have to pick up a new medication, stronger and in a larger dose.
Can it be used during pregnancy? We will review the reviews on Vilprafen below.
Pregnancy and lactation
Antibacterial substances from the macrolide category are not prescribed for the treatment of inflammatory diseases of women who are in the period of bearing a child, since they can freely pass through the placental barrier, causing severe disturbances in the development of the fetus.
The medicine "Vilprafen" during lactation is also contraindicated for use. If a therapeutic course is needed with this medication, a woman should temporarily stop feeding her baby with milk or consult a specialist for recommendations when choosing an alternative treatment.
Side effects
According to reviews on "Vilprafen", with the correct use of this drug and strict adherence to the dosages indicated in the instructions, it is well tolerated by patients, but in some situations the following undesirable effects may occur:
- From the digestive organs: symptoms of dyspepsia, abdominal pain, excessive salivation, vomiting, heartburn, ongoing diarrhea, the development of inflammatory processes in the intestines (in rare cases).
- On the part of the bile ducts and liver: an increase in the activity of liver transaminases, impaired bile excretion (rarely), a change in the functionality of the gallbladder, as a result of which jaundice is considered a frequent side effect.
- Allergic skin reactions: pathological rashes, urticaria, Quincke's edema, anaphylactic shock (extremely rare).
This is confirmed by the instruction and reviews to Wilprafen.
Overdose symptoms
In clinical medical practice, cases of overdose in patients with the correct use of this medication have not been reported. With a significant increase in the dosages recommended in the instructions, patients may develop complications from the digestive system - severe nausea, vomiting, changes in the liver, diarrhea. In some situations, liver failure may develop.
The complete instructions for Vilprafen should be studied in advance.
Drug interaction
It is necessary to avoid the simultaneous use of the drug with antibacterial agents from the category of cephalosporins or penicillins, since this can provoke the formation of liver failure, severe liver damage, diarrhea and, as a result, dehydration of the body. In severe cases, the development of coma was observed in patients.
With the concomitant use of antibiotics of the macrolide class with xanthines in patients, severe intoxication of the body can be noted.
When using the drug "Vilprafen" during treatment with antihistamines, it is likely that serious cardiac dysfunctions, in particular, cardiac arrhythmias, can occur.
When taking tablets of this drug in parallel with hormonal contraceptives, it is possible to decrease their effectiveness, which should be mandatory to warn patients in order to avoid the occurrence of an unwanted pregnancy. During antibiotic therapy, experts recommend the use of additional contraceptives (optional).
So it is said in the instructions for use for the drug "Vilprafen."
Special recommendations
Elderly people, as well as patients with severe impaired liver or kidney function, this medication is prescribed with extreme caution. During therapy, constant monitoring of the patient’s general health and clinical blood picture is necessary.
There are many drugs that are similar in action and composition to the antibiotic Wilprafen.
Analogs
Analogues of this drug are drugs that are similar not only in composition, but also in therapeutic effects on the body.
These include:
- Erythromycin is the first drug from the macrolide class. It is produced in tablet form and as an ointment for the eyes. It has the same therapeutic effect as Vilprofen, has similar indications for use. Effective in the treatment of ENT infections - scarlet fever, brucellosis, pertussis, gonorrhea, tonsillitis, diphtheria and syphilis. The cost of packaging this medication is approximately 60 rubles.
- Roxithromycin is an antibacterial drug that fights against such pathologies as brucellosis, erysipelas, phlegmon, scarlet fever, pharyngitis, whooping cough, pyoderma, trachoma, tonsillitis. It is also used in the treatment of female inflammatory processes of the vulva, cervix, vagina. Side effects are similar to those that occur when using Vilprofen, only they are joined by some more disturbances in the nervous system. The cost of this tool is 160-600 rubles (depending on the form of release and dosage).
- Spiramycin-Vero is a medical product intended for the treatment of skin lesions, respiratory diseases, asthma, meningitis and female pathologies. The drug is also used to prevent diphtheria. Release form: tablets, solutions for intravenous administration, the cost ranges from 160 to 300 rubles.
- “Clarithromycin” is a medication belonging to the macrolide category. The effectiveness of its effect is aimed at genital infections, and is also suitable for the treatment of laryngitis, otitis media, pharyngitis, etc. It helps with furunculosis. The price of the drug varies from 90 to 450 rubles.
Cost
The price of tablets of this medication in a dosage of 500 mg is approximately 480-560 rubles per package. It depends on the region and the pharmacy network.
Reviews on Wilprafen
A lot of positive reviews have been left about this medication, which contain information about its effect on the body in certain inflammatory diseases. When treating with these pills, people observed a significant improvement in their general well-being and a significant subsidence of the symptoms of an infectious lesion of various systems or organs.
According to patients' reviews of Vilprafen, it can be noted that already in the first days of treatment, the main manifestations of the pathology disappeared or became much weaker. This drug is especially effective in diseases of the respiratory organs, as well as in the treatment of female diseases of an infectious nature of origin.
There are practically no negative reviews about Vilprofen, however, there is some information about its poor tolerance, but this applies to extremely rare cases. This category of patients noted the development of such adverse reactions as indigestion, stool, pain in the abdomen. It was not necessary to cancel the medicine, since such symptoms quickly disappeared against the background of symptomatic therapy.
The reviews of doctors suggest that this medication should be used only for its intended purpose, and in no case independently, since it has a certain number of contraindications and adverse reactions. In general, experts consider this antibiotic very effective and prescribe it for diseases of moderate and severe degree.