The Kenalog medication helps to remove inflammation, cope with severe allergy attacks. It is widely used in medicine. The drug is a hormonal glucocorticoid, but, unlike similar drugs, rarely causes side effects. If, nevertheless, against the background of the use of this drug, negative reactions have occurred, then analogues are prescribed, “Ketalog” is canceled in this case.
The composition and form of production
The drug "Kenalog" is available in the form of tablets and suspensions for injection.
One tablet of the medicine contains 4 mg of the active component of triamcinolone. As auxiliary substances involved: magnesium stearate, starch, lactose monohydrate, talc, povidone.
The ampoule may be composed of 10 mg or 40 mg of triamcinolone acetonide. As additional components were used: benzyl alcohol, polysorbate, sodium carboxymethyl cellulose, sodium chloride, as well as water intended for injection. Analogs do not always contain similar constituent substances.
Kenalog is produced in Slovenia by Krka. In tablet form release in one package contains 50 pills. If the drug is in ampoules, then in a cardboard box there are five pieces. Ampoules produce 10 or 40 ml.
The cost of tablets is 250-300 rubles, ampoules - about 450-500 rubles. Analogs are not always cheaper. Kenalog, for example, costs less than Diprospan.
Indications and contraindications
Analogues of Kenalog can always be replaced if necessary. The specified drug is prescribed for shock of various origins. It can be cardiogenic shock, traumatic, burn, surgical or toxic. In this case, “Kenalog” is used when the treatment is not successful.
The drug “Kenalog” (analogues and their use in the treatment of diseases of the musculoskeletal system gives a tangible result) is prescribed for severe allergies. Prescribe medication for anaphylactoid reactions, including blood transfusion and anaphylactic shock. Indications for use are asthmatic status, rheumatoid arthritis, as well as bronchial asthma.
The drug is used for systemic pathologies of connective tissue. The appointment is a thyrotoxic crisis and an acute stage of adrenal insufficiency. Doctors use Kenalog for acute hepatitis and hepatic coma, as well as for intoxication of the body with cauterizing fluids. The tool is recommended for the prevention of cicatricial narrowing and to reduce the inflammatory process.
The medication is used intraarticularly for diseases such as synovitis, tendonitis, traumatic arthritis and bursitis.
The drug is used for intramuscular and intradermal administration for total and nesting alopecia, lichen planus, keloid scars, psoriasis, annular granuloma, and also limited neurodermatitis.
The contraindication to the use of the Kenalog drug (analogues and their use in medical practice is allowed, instead of the specified drug, if the latter is poorly tolerated by the patient) are the acute stages of psychosis, which are in the amnesis. You can not prescribe a medication in the active stage of development of tuberculosis, with myasthenia gravis, which is accompanied by various neoplasms with the appearance of metastases, duodenal ulcer and stomach, diverticulitis, arterial hypertension. Do not use the drug for Itsenko-Cushing's syndrome, thrombosis, diabetes mellitus, renal failure, and a history of embolism.
The ban on use is osteoporosis, all kinds of hidden infectious foci, syphilis, as well as amyloidosis. It is not recommended to use the medicine in the presence of fungal diseases, infections caused by viruses, including Varicella zoster, Herpes simplex. Contraindications are amoebic infections, tuberculosis and gonococcal arthritis, poliomyelitis. A ban on the use of the drug is the vaccination period, skin lesions that are infected in nature, as well as lymphadenitis, which manifested itself after BCG vaccination.
The drug is not prescribed for children under 16 years of age, unless there is an urgent need. Do not use it during the first five months of pregnancy. Prolonged use of Kenalog during pregnancy can slow the development and growth of the fetus and cause adrenal atrophy in the unborn baby. The drug passes into breast milk. Therefore, during treatment, they should interrupt breastfeeding.
"Kenalog": instructions for use
Analogs, like Kenalog, should be prescribed by a doctor and only in cases of urgent need, since these drugs are hormonal. Kenalog medicine has two forms of release: suspension for injection and tablets.
Tablets are prescribed for adults 4-16 mg per day. This dose is divided into 2 or 3 doses. After improving the patient's condition, the dosage is gradually reduced by 1-2 mg after 2-3 days. Thus, they reach the use of a maintenance amount of the drug, equal to 1 mg per knock, and then completely cancel the medicine.
Before using Kenalog ampoules (analogues have a similar effect and have a similar application pattern), they must be shaken well. The drug can not be administered intravenously and subcutaneously.
For symptomatic indications, adults are given a 40 mg suspension intramuscularly. This dosage is used at the beginning of drug treatment. The injection is administered slowly, once every four weeks. If the patient tolerated the first injection well, then the drug is subsequently injected every 2-4 weeks at 40-80 mg. If necessary, a single dose may increase to 100 mg. To prevent subcutaneous atrophy, the medicine is injected deep into the muscle tissue. After the injection, an alcohol wipe is applied to the injection site.
Seasonal fever and other allergic pathologies are eliminated once a year, with one injection of 40 mg, during the pollen season. If there is a need for several injections, then they are administered with an interval of four weeks.
The dosage for intra-articular administration is determined by the parameters of the joint itself and the severity of the disease. For adults and children over the age of twelve, the dose for small joints is taken up to 10 mg, for medium - up to 20 mg, large - up to 20 or 40 mg. If several joints are affected at once, then the amount of medicine is increased up to 80 mg. To quickly relieve symptoms of the disease, Kenalog can be administered with a local anesthetic that does not contain a vasoconstrictor. Injections are set so that a depot of the drug is not formed in the subcutaneous adipose tissue. The introduction of the drug should be carried out with complete disinfection. Before articular injection, the skin is prepared in the same way as for surgical intervention. You can reuse the medicine after two weeks.
If the drug is injected directly into the lesion (for example, with bursitis, exostosis and the inflammatory state of the periosteum), then for adults and in children over the age of twelve, a dose of 10 to 40 mg is taken. It depends on the area of ​​the lesion and the location of the pathology. With the introduction of the drug in an amount of less than 10 ml, Kenalog ampoules of 10 mg should be used. The drug is diluted with a solution of sodium chloride and fan-shaped put in the zone with maximum pain. The formation of a large depot of medication should be avoided. It is allowed to mix Kenalog with a local anesthetic.
In the treatment of exostoses, the drug is administered with a thick cannula, after the procedure of aspirating the contents and directly into the space of the cyst. Reuse of injections after two weeks is acceptable.
If an injection is made into a site with subcutaneous lesions, then 40 mg of the solution is diluted with a local anesthetic, without a vasoconstrictor component. The injection is placed horizontally in the area located between the skin and the subcutaneous layer. This is done to obtain anesthesia for infiltrate. The dosage is selected at the rate of 1 mg per 1 cm 2 of the affected skin. If several foci are treated at the same time, then a single dosage should not exceed 30 mg for adults and 10 mg for children.
With keloids, the drug in a dose of 40 ml, without diluting, is injected directly into the scar. You can not put the medicine subcutaneously. Repeated use is possible after two weeks. The duration of drug treatment depends on the severity of the disease, its development and, as a rule, is determined by the doctor.
The medicine can be used both once (hay fever), and for several years (bronchial asthma in a severe stage of development). If after 3-5 injections there are no signs of improvement, then the drug is canceled and analogs in ampoules or tablets are prescribed instead of the “Kenalog” medication.
Reviews on the drug "Kenalog"
He notes that the “Kenalog” preparation should be used only as prescribed by the doctor for use. Reviews (if necessary, the attending physician will always help you choose the analogues) claim that the medicine resolves subcutaneous scars, helps to remove halazions (they disappear after 1-2 weeks after the injection), saves you from lower back pain, joints and with shoulder-shoulder periarthritis. Injections with Kenalog are done with heel spur and bronchial asthma.
Among the negative aspects note the hormonal composition of the drug “Kenalog” reviews (analogues have a similar effect and also contain hormones). Patients say the drug can cause uterine bleeding and bring down the menstrual cycle. After its use, pain in the stomach, heartburn and nausea are observed. It does not give the desired effect with seasonal allergies.
Analogs
If Kenalog is not suitable for treatment, analogues in ampoules and tablets can easily replace it. The following medicines are the most popular substitutes:
- "Flosteron." Produced in Slovenia in the form of suspensions for injection. Five ampoules cost about 200 rubles.
- Depot-Medrol. It is made in Belgium in the form of injectable suspensions. The price of one bottle is 70-100 rubles.
- Solu-Medrol. It is produced in the USA in the form of a lyophilisate for the preparation of an injection solution. The price of a bottle of 250 ml with a solvent is 400 rubles.
- "Dexamethasone." Available in the form of tablets, eye drops and injection solution. Ten tablets cost about 40 rubles, eye drops of 10 ml - 60 rubles, and 4 ampoules of 1 ml -130-140 rubles. The medicine is produced in Belarus, Ukraine, Russia and Slovenia.
- "Polcortolon." It is produced in the form of tablets and ointments. Fifty tablets cost 350-400 rubles. It is made in Poland.
- "Triacort." It is made in Russia in the form of ointment. A tube of 10 g costs about 100 rubles.
- "Fluorocort". It is made in Hungary. Ointment. It costs from 150 to 200 rubles.
- Medrol. Country of origin - Italy. Available in tablets. Thirty pills cost 150 rubles.
- "Cortef." It is made in Canada. Tablets. The price of a hundred capsules is about 400 rubles.
- Diprospan. It is made in Belgium in the form of ampoules for injection and in disposable syringes. The price of one ampoule is 200 rubles.
These and other drugs can be a worthy alternative to Kenalog. Analogues and substitutes should be selected by the doctor, after a thorough assessment of the patient's condition.
Analogue "Solu-Medrol"
When negative reactions appear, they are always ready to replace the Kenalog 40 medicine with analogues. One of these drugs is Solu-Medrol. The active substance of the drug is methylprednisolone. A medicine is produced in the form of a lyophilisate for the preparation of an injection solution.
The drug is prescribed for severe endocrine diseases, rheumatic pathologies, systemic diseases of the connective tissue and skin ailments. Helps with severe allergies and inflammatory processes with eye damage. Effective for diseases of the gastrointestinal tract and pathologies of the respiratory tract. The medicine has many other indications for use.
The medical tool has only positive reviews. Patients note that Solu-Medrol helps in the most hopeless situations, such as multiple sclerosis, rheumatoid arthritis and others. After its use, pain quickly passes.
With multiple sclerosis, the condition improves after a week of daily use of the drug. Someone says that with frequent use, the hormone is not as effective as the first time, but it helps anyway.
Which is better, “Solu-Medrol” or “Kenalog”, only the doctor will say, assessing the patient’s health status.
Russian analogue "Triacort"
The drug "Triacort" in some cases can replace the drug "Kenalog" (analogues act in a similar way, and sometimes more effective than this tool). The active substance of the drug is triamcinolone acetonide. It is made only in the form of ointment.
"Triacort" has a pronounced anti-inflammatory, antipruritic and anti-allergic qualities. It is used for diseases of the skin, such as eczema, dermatitis, psoriasis, allergic manifestations. It can be used only externally, in contrast to Kenalog, which has a wider range of applications and is used not only locally, but also intramuscularly, intraarticularly.
Patients have a good opinion about this drug. They say that in a matter of days it is able to remove allergic dermatitis. Helps with eczema and psoriasis. In case of skin pathologies, Triacort can replace Kenalog.
Analogs (dosage of drugs replacing Kenalog should be selected by a doctor) can have a different form of release. If you need drugs that are used orally or by injection to replace Kenalog, then Triacort will not work, you will need to choose another medication.
Substitute "Polcortolon"
Able to replace, if necessary, the drug "Kenalog 40" analogues. The most common is Polcortolon. The drug is similar to Kenalog for the active substance. Available in the form of an aerosol, tablets and ointments. The medication is not used for injection. This is its main difference from Kenalog.
Indications for use are allergic reactions, pathologies of the endocrine system, diseases of the musculoskeletal system. The medicine is used for skin ailments, rheumatism, connective tissue diseases and other pathologies. Polkortolon, as well as Kenalog, has a wide range of applications.
Patients note that the drug helps to cope with eczema, dermatitis and other allergic rashes. Patients with asthma take this medicine all the time. There are people who note the occurrence of side effects after the use of "Polcortolone."
Diprospan
The medicine “Kenalog” is an analogue of “Diprospana”. Both drugs are synthetic hormones. They differ in active components, in “Diprospan” the active substance is betamethasone dipropionate. "Kenalog" is a medicine of the past generation, has larger crystals, which with frequent use can destroy cartilage tissue. When treating the same diseases, “Diprospan” gives greater efficiency than “Kenalog”, but it costs more.
The medicine "Diprospan" is made only in the form of a suspension for injection. Packed in glass ampoules and disposable syringes. Indications are the same as those of Kenalog.
The medication has anti-allergic, immunosuppressive, desensitizing, anti-inflammatory, anti-shock and anti-toxic properties. It is released from pharmacies only by prescription. It is well tolerated by patients, but sometimes it can cause adverse reactions.
Most patients are satisfied with the effectiveness of this medicine. It is used for allergies to pollen, dermatitis, psoriasis, eczema, rheumatoid arthritis, calcaneal spur, arthrosis. People warn that with prolonged use, the medication can cause severe side effects. In these cases, it is replaced with “Kenalog 40”. The analogue of "Diprospana" allows you to continue the treatment that has begun.
Dexamethasone - a substitute for Kenalog
Analogues "Kenalog" (the instruction for this medicine warns of contraindications and possible side effects) has, they are sold in almost every pharmacy. As a rule, they are prescribed by doctors. The drug "Dexamethasone" can replace this medicine. The product is available in the form of tablets, drops for the eyes and in injection form. The active substance is dexamethasone. Contains a fluorine atom. It is characterized by immunosuppressive, anti-inflammatory, desensitizing and anti-allergic effects.
The drug is well tolerated by patients. It is often alternated with Kenalog and Diprospan. , . «» , . , , . , . , .