Allergies can occur in every person for some specific factors. There are a huge number of varieties of allergies, ranging from a banal allergic rash to severe species, edema. It is worthwhile to learn more about the syrup for allergies "Lordestine" and its most common analogues.
What is a disease?
The most common symptom of an allergy is swelling of the nasal mucosa, which leads to nasal congestion, rhinitis, that is, an allergic rhinitis. The disease manifests itself with various rashes on the skin, primarily it happens on the stomach, on the face and on the elbow bends. Inflammation and redness of the eyes, that is, allergic conjunctivitis, can occur. These manifestations are known to everyone, and usually they do not raise a question in terms of diagnosis. But there are unexpected manifestations of allergies, and even doctors do not always know that certain diseases are of a similar nature. To get rid of allergies, there are two ways:
- It is necessary to take anti-allergic drugs.
- Identify an allergen, various tests are done for this. After identifying the pathogen, doctors recommend avoiding contact with this substance and, in some cases, taking anti-allergic drugs.
There are many different antiallergic drugs, such as syrup "Lordestine".
general information
Lordestine is a clear and colorless syrup that smells like almonds. The producer of syrup "Lordestine" is JSC "Gedeon Richter", Romania. ATX code R06AX27. The active substance of this drug is desloratadine. The drug is available in the form of tablets and syrup (0.5 mg / ml). The syrup is sold in bottles of 60 ml, 120 ml and 150 ml, the glass comes in the kit, which measures the dosage of the drug. Syrup is sold in dark glass bottles sealed in cardboard boxes.
Pharmacology
The pharmacological group of the drug is a blocker of H1-histamine receptors. Antiallergic drug. In other words, a long-acting histamine antagonist.
It is an anti-allergic agent. Desloratadine is one of the active metabolites of loratadine. The active substance helps to alleviate the course of allergic reactions. Also, this drug has other actions: antipruritic and antiexudative, it prevents tissue swelling and smooth muscle spasm.
Indications
It is necessary to indicate the indications for the use of syrup "Lordestine". This drug has no effect on the central nervous system, does not cause drowsiness, and does not affect the speed of psychomotor reactions. The antiallergic drug begins to act within thirty to forty minutes after administration and is valid for 24 hours.
Take the drug inside, according to the instructions. The syrup is well absorbed into the gastrointestinal tract. Thirty minutes after administration, it can be determined in blood plasma. The drug is excreted from the body through the kidneys and through the intestines for more than 27 hours.
Syrup "Lordestine" is used for allergic rhinitis (it facilitates and eliminates sneezing, nasal congestion, mucus from the nose, eliminates itching in the sinus mucosa, eliminates itching of the palate, prevents redness of the eyes, and eliminates lacrimation). Also, this tool can be used for urticaria (it reduces or eliminates skin itching, relieves rashes).
Syrup "Lordestine" is taken inside, you need to drink it with water, you can take it before meals, and after eating.
Doses
Dosage:
- Children aged one to five years should be taken in the following dosage - 1.25 mg (which corresponds to 2.5 ml of syrup), you need to give the drug once a day.
- Children from six years to eleven years of age should take the drug in this dosage - 2.5 mg each (which corresponds to 5 ml of syrup), should be given once a day.
- Adults and adolescents over the age of twelve years should take syrup in this dosage - 5 mg each (which corresponds to 10 ml of syrup), should be given once a day.
To measure the right amount of the drug correctly, you need to use the dosing cup, which is included in the kit. This cup can measure from 2.5 ml to 20 ml of liquid. If, after the end of the course of treatment, the symptoms do not disappear or reappear, then you need to urgently consult a doctor for help and advice. This drug should only be used in accordance with the symptoms and take the doses that are indicated in the instructions, which are in the package with syrup.
Side effects
Side effects of the syrup "Lordestine" were seen in children aged six months to two years. It was diarrhea, fever, insomnia. In children aged two to eleven years, side effects were such as diarrhea, fever and insomnia. However, there are fewer such cases than in children aged six months to two years.
But in children who are twelve years of age or older, when taking this drug, side effects such as headache were found. In adults and children over the age of twelve, when taking this antiallergic drug, such undesirable effects as fatigue, headache and dry mouth occurred, but the percentage of these manifestations is very small. All data on side effects are taken from clinical studies and observations of patients who took this drug.
Also, an undesirable effect from taking this syrup can be a hallucination, this can be found extremely rarely, but it is still possible. Side effects from the nervous system are common headaches and insomnia, dizziness, cramps, fatigue, and drowsiness are very rare. When taking “Lordestine” syrup, you can observe such side effects as increased activity of liver enzymes, increased bilirubin, hepatitis, and very rarely you can encounter such side effects of the body on this remedy as jaundice. While taking this medication, you can rarely diagnose abdominal pain, nausea, dyspepsia, but most often a side effect is diarrhea (in children under two years of age) and dry mouth.
It is also extremely rare to detect tachycardia, a frequent heartbeat in a person who takes this syrup. In children under the age of two years, a fever may appear, and babies can quickly become tired while taking this medicine. If the patient has noticed that some side effect is exacerbated or if side effects have appeared that are not in the instructions, then you should immediately contact a medical institution for help.
Contraindications
Contraindications syrup "Lordestine" are also recorded in the annotation to the tool. Take the drug for people who are hypersensitive to desloratadine, loratadine, or to another component that is contained in the syrup, is prohibited. Do not use this antiallergic drug for pregnant women and mothers who are breastfeeding. Children under the age of one year should not be given this syrup. It is also not recommended for people who have impaired absorption of sorbitol or have been diagnosed with sorbitol dehydrogenase deficiency, which is part of the lordestine syrup. A person suffering from intolerance or malabsorption of sorbitol can often not tolerate other sugars. With extreme caution, you need to take this medication to people who have kidney failure.
During pregnancy and lactation
Syrup should not be used by pregnant women and girls who are breastfeeding because of the lack of clinical data that it is safe to use this drug during these periods.
After opening the bottle, the shelf life of the syrup is 28 days.
Carefully
It is not established whether the drug is effective and safe for children under the age of 1 year; therefore, it is necessary to take the use of syrup in the treatment of babies with special seriousness in order to avoid undesirable consequences.
In people with renal insufficiency, the amount of desloratadine in the blood plasma increases at times, so this antiallergic drug should not be taken by such people.
Although taking the medication in recommended doses does not affect the ability to drive vehicles and work with mechanisms, sometimes therapy with this drug can cause drowsiness or fatigue. In such cases, you need to be careful.
Overdose was not detected in patients who exceeded doses even five times allowed. But if it still happened that a person drank a large amount of the drug, he should immediately seek qualified help at the nearest medical institution. Doctors recommend in such cases to rinse the stomach, take activated charcoal. If necessary, but symptomatically eliminate the action.
Eating and taking grapefruit while using this antiallergic drug does not affect its effect and effectiveness. You can not drink alcohol during treatment, as there have been cases when the parallel intake of alcohol-containing drinks and syrup provoked undesirable conditions or severe intoxication. Therefore, you can not drink syrup and alcohol at the same time.
Storage
Keep Lordestine syrup in a place that will be inaccessible to children. Syrup is saved at an air temperature of 25 ° C, but not higher. The shelf life of the syrup is two years from the date of manufacture. Date of manufacture and batch number are indicated on the package. This medicine is dispensed without a prescription.
Analogs
There are also a number of analogues of syrup "Lordestine", which are similar in composition. In addition to the following, you can buy an anti-allergic spray. But the form of drugs in tablets is more common.
Analogs:
- "Alestamine" (film-coated tablets).
- "Blogir - 3" (release form - five-milligram lozenges, syrup), manufacturer Croatia, the average cost of tablets is 5 pieces - 100 rubles, 10 pieces - 150 rubles, 30 pieces - 300 rubles.
- "Desal" (film-coated tablets, 5 milligrams), production of Iceland, the average cost of 250 rubles for 10 tablets, 300 rubles for 30 tablets.
- "Desloratadine" (coated tablets contain 5 mg of desloratadine), manufacturer Russia, the average cost in pharmacies is 190 rubles, ten tablets per pack.
- "Desloratadin Canon" (film-coated tablets contain 5 mg of the active substance desloratadine), manufacturer Russia, pack of ten tablets, the average cost of the drug is two hundred rubles.
- "Desloratadine - Teva" (film-coated tablets contain 5 milligrams of the active substance desloratadine), manufacturer Israel, the average cost is 300 rubles for seven tablets.
- "Desloratadine-Pharmaplant" (film-coated tablets contain 5 mg of the active substance desloratadine).
- "Desloratadine hemisulfate" (film-coated tablets contain 5 milligrams of the active substance desloratadine).
- Nalorius (film-coated tablets contain 5 mg of the active substance desloratadine).
- Ezlor (film-coated tablets contain 5 milligrams of the active substance desloratadine), manufacturer Russia, the average cost of 300 rubles per ten tablets.
- "Ezlor Solution Tablex" (film-coated tablets contain 5 mg of the active substance desloratadine).
- "Elisei" (film-coated tablets contain 5 mg of the active substance desloratadine), manufactured in Ukraine, the average cost in pharmacies is 370 rubles per package, which contains 30 tablets.
- According to the instructions for use for children, Erius syrup is produced in Germany. The average cost of 60 ml syrup is 700 rubles, the cost of 10 tablets is 600 rubles. Based on the instructions for use, the Erius syrup for children is prescribed only after six months at 1 mg per day. With age, the dose increases. Appointed only by a doctor.
- Eslontin (film-coated tablets contain 5 mg of the active substance desloratadine).
Reviews of people who used both the main drug and analogues
From consumer reviews, you can see that in most cases there were no side effects when taking, but there were cases when patients showed a slight deterioration. The average cost of this drug is 200 rubles. According to reviews, the cheapest analogue is Desloratadine, which is available in tablets and is effective for allergic rhinitis and urticaria. Analogues are used by those people who have poor tolerance to the original medicine, but it is impossible to replace medicines on their own. You need to see a doctor, he will help you choose an analog.
Doctors give a rather high assessment of the syrup “Lordestine”. This drug quickly begins to act and helps get rid of the unpleasant symptoms of seasonal allergies. That is why it is often prescribed to allergy sufferers.