The drug "Raunatin" is a drug whose action is aimed at lowering pressure. The basis of the medicine is a substance obtained by processing the roots of rauwolfia (a plant common in India). Before use, you must familiarize yourself with the official instructions for use of Raunatin. Prices, reviews and analogues of the drug will be discussed below.
Pharmacological group
This medicine belongs to the group.
- antiadrenergic agents of central action;
- antihypertensive drugs;
- alkaloids of rauwolfia.
According to the ATX classification, the drug is assigned the code C02A A04.
Composition and form of release
Raunatin is produced in the form of biconvex tablets and coated with a green shell. Every 10 tablets are packed in cell plastic blisters. A cardboard box is used as packaging. It can have from 1 to 5 blisters.
The main active ingredient of the tablets is 2 mg of raunatin.
The list of excipients includes:
- glucose monohydrate;
- sucrose (sugar);
- calcium stearate;
- potato starch.
The smooth enteric coating of the tablet is made from sucrose, basic magnesium carbonate, titanium dioxide, povidone, aerosil, talc, beeswax and liquid paraffin.
Pharmacokinetics
According to the instructions for use of “Raunatin”, the basis of the drug is raunatin, which is a combination of alkaloids obtained from the roots of rauwolfia. The list of alkaloids contains serpentine, reserpine, aymalin and some others. Tablets are used as antiarrhythmic and antihypertensive drugs, in addition, they have a beneficial effect on the central nervous system and have a calming effect.
When it enters the gastrointestinal tract, the active substance is actively absorbed. Withdrawal of the drug occurs through the kidneys with urine (in an amount of about 8%) and through the intestines with feces (about 80%).
When prescribed "Raunatin"
The official instructions for the use of “Raunatin” say: the reason for the appointment of this drug is the diagnosis of arterial hypertension. Patients may have a moderate or mild form of the disease.
Dosage and route of administration
The choice of dosage and dosage regimen in each case is individual. It depends on such characteristics as the severity of the disease, the age of the patient, his general condition and the presence (or absence) of other drugs in the treatment.
Reception "Raunatina" should be carried out after eating. Often the following scheme is used, indicated in the instructions for use of Raunatin tablets:
- 1st day of treatment - 1 tablet (in the evening);
- 2nd day - taking the medicine 2 times a day, one tablet;
- 3rd day - take 3 times a day for 1 tablet.
According to this scheme, the daily dose is increased to 4-6 tablets. In such an amount, the medicine should be used until a lasting therapeutic effect is achieved. After this, the dosage is gradually reduced to 1-2 tablets per day.
During the course of treatment, the doctor should regularly monitor the patient's condition. This is necessary for timely correction of the dosage of the drug according to the instructions for use of “Raunatin”. At what pressure should stop taking, depends on individual indicators.
Course duration may vary. With prolonged use (longer than 4 weeks), the maintenance daily dose should not exceed 1 tablet.
Contraindications
Before starting therapy, you should familiarize yourself with the contraindications indicated in the instructions for use of Raunatin. This drug is not prescribed in the following cases:
- state of depression;
- arterial hypotension;
- peptic ulcer of the duodenum and stomach;
- coronary circulatory failure;
- pregnancy period;
- pathology of the aorta;
- organic myocardial damage;
- nephrosclerosis;
- hypersensitivity to alkaloids;
- children under 18 years old.
Destination Features
In some cases, taking the drug should be done with caution.
In the case of a planned operation, the medicine is canceled a few days before the expected date of surgery. When an unscheduled operation involving general anesthesia is due, the patient should undergo atropine premedication.
In the case of the use of electric pulse therapy, the drug is not recommended to be used before the session.
In cardiology, Raunatin can be used to treat those patients who are not suitable for other antihypertensive drugs. Many people with hypertension are wondering when it is possible to use Raunatin (at what pressure). Instructions for use do not give clear recommendations, since each person has low individual pressure indicators.
Side effects
In most cases, patients tolerate this drug well. Side effects are rare. Patients may complain of:
- increased sweating of the body;
- development of a depressive state;
- bradycardia;
- asthenia;
- pain in the heart;
- increased signs of angina pectoris;
- decreased libido.
Hypersensitivity to one of the components of the composition can cause allergic reactions, including swelling of the mucous membrane, urticaria and skin rashes.
Long-term use in some cases leads to sleep disturbances, the appearance of symptoms of parkinsonism and impaired liver function. Most of these adverse reactions are temporary and are eliminated after discontinuation of the drug.
Overdose
If the daily dosage indicated in the instructions for use of Raunatin has been exceeded, symptoms similar to side effects may appear. With a slight overdose, bouts of severe weakness, excessive sweating, and arterial hypotension are possible. With a strong excess of the dose, there is a risk of loss of consciousness and coma.
If the dosage has been exceeded, gastric lavage is performed and the absorption intensity is reduced by using activated charcoal. Next, symptomatic treatment is carried out, since there is no specific antidote for this drug.
The symptoms of parkinsonism are eliminated by Cyclodolum and forced diuresis.
With reduced pressure, the patient is recommended to take a horizontal position. In this case, the legs should be raised above the level of the head. If necessary, the introduction of mesatone or reopoliglyukin.
Impact on the ability to control mechanisms
Taking this drug can cause a decrease in concentration and accuracy. For this reason, patients should be careful when driving and when engaging in potentially hazardous activities.
Interaction with other medicines
When prescribing complex treatment, it is important to consider the use of other drugs. “Raunatin” is not combined with various groups of medicines.
Saluretic and antihypertensive drugs are able to enhance the effect of alkaloids, so “Raunatin” is prescribed carefully, in small doses.
Interaction with “Dopegit” can provoke severe depressive states. It is better to refuse such a complex.
Tablets are able to enhance or weaken the effects of other drugs:
- Digitalis has an increased arrhythmogenic effect;
- “Anaprilin” has a bradycardic and hypotensive effect;
- morphine weakened analgesic property;
- muscle relaxants, barbiturates, cholinomimetic and adrenomimetic drugs increase efficiency.
Alkanoid drugs should be used with extreme caution. In the list of these medicines:
- cardiac glycosides;
- guanethidine;
- beta-blockers;
- quinidine.
The simultaneous use of antihypertensive drugs and medications for general anesthesia can lead to a collaptoid state.
With A-adrenoreceptor blockers, there is a risk of orthostatic collapse.
Analogues of the drug
According to medical data, this drug has no analogues according to the ATX code. As for drugs with a similar effect, among them are called alkaloids of Rauwolfia, “Reserpine” and dry extract of Rauwolfia.
At the same time, all named analogues of “Raunatin” have instructions for use, prices and reviews may vary. They have their own side effects, dosage regimen and possible contraindications. To avoid complications, you should consult your doctor before replacing a medicine.
Storage conditions and shelf life
During storage, it is important to maintain certain conditions, among which - the absence of direct sunlight, protection from moisture, ambient temperature not higher than 25 degrees. Shelf life is 24 months from the date of manufacture.
Instructions for use "Raunatina" and reviews
Reviews of doctors regarding this medication are somewhat divided. On the one hand, the medicine has established itself as an effective tool. However, he has many contraindications and side effects. In addition, a careful selection of other drugs for complex treatment is required.
Due to the persistent therapeutic effect of the tablets, patients often leave positive reviews for Raunatin. Instructions for use and doctor's recommendations allow you to accurately dose the product. Many patients emphasize that mild side effects appeared only at the very beginning of treatment.
As a result of the foregoing, we can conclude: “Raunatin” is a fairly effective drug prescribed for arterial hypertension. It is relatively easy to use, and most patients tolerate it well (subject to the instructions for use). The price of Raunatin is relatively low, which is also considered an advantage. Self-medication is strictly not recommended. This is explained by the need for careful selection of dosage and regular monitoring of the patient's condition.