Consider why the "Rehydron" powder is prescribed. This is a drug intended for enteral use with rehydration and detoxification effects.
The dosage form of this agent is a powder for the preparation of a solution that should be taken orally. It is a crystalline mass of white. After the powder is dissolved in water, the resulting solution takes the form of a clear, odorless, colorless liquid with a salty-sweet taste. The powder is packaged in laminated bags of aluminum foil, packed in cardboard boxes of 4 or 20 pieces.
The complex of active substances of the drug "Regidron" includes:
- dextrose;
- sodium chloride;
- sodium citrate;
- potassium chloride.
pharmachologic effect
To find out why the Rehydron powder is prescribed, we describe its pharmacological effect. Glucose present in the preparation promotes the absorption of citrates and salts and supports metabolic acidosis. The osmolarity of the prepared solution is 260 mosm / l, the medium is slightly alkaline (pH 8.2).
Compared with conventional solutions for rehydration therapy, this medicine has the lowest osmolarity. In addition, in comparison with analogues in the powder content from poisoning "Regidrone" sodium concentration is quite low, and the level of potassium is slightly higher, given that hypoosmolar solutions are the most effective. With a low concentration of sodium, the likelihood of developing hypernatremia decreases, and with too high a level of potassium, its level is quickly restored.
The pharmacokinetics of glucose and electrolytes, which are part of the drug, corresponds to the pharmacokinetics of these substances in the body.
Why is Rehydron Powder prescribed?
Indications for the use of the drug are:
- the need for acidosis correction;
- prevention of water-electrolyte imbalance during physical and thermal stresses caused by intense sweating;
- restoration of electrolyte and water balance with severe diarrhea (including cholera) or heat damage that caused changes in water-electrolyte metabolism;
- rehydration therapy for acute diarrhea with mild or moderate dehydration.
The main thing is not to self-medicate.
List of contraindications
According to the instructions for use, Regidron powder is contraindicated in the following situations:
- unconsciousness;
- diabetes mellitus (any type);
- functional impairment of the kidneys;
- bowel obstruction;
- high sensitivity to the components of the drug.
This must be considered before the appointment.
Instruction manual
Find out how to drink "Rehydron" for adults and children? The ready-made solution is intended for enteral use, for this, in 1 liter of boiled chilled water, you need to dissolve the contents of 1 package of the medicinal product. The following dosage is recommended:
- Diarrhea: Take 50-100 ml of the solution every 3-5 minutes. During the use of a nasogastric tube, this procedure should last at least 3-5 hours. With a mild course of the pathological process, the daily dosage should be 40-50 ml per 1 kg of the patient's weight, with an average course of 80-100 ml per 1 kg. The instruction of "Rehydron" for children with diarrhea should be strictly observed.
- Maintenance treatment: 80-100 ml per 1 kg of weight per day during the period of diarrhea, until the electrolyte and water balance are completely restored.
- Heat cramps, polyuria, thirst: 100-150 ml is taken for 30 minutes, after which it must be repeated every 40 minutes until the pathological symptoms disappear.
Adverse reactions
During the administration of a medication, allergic reactions may occur. If you exceed the dosage of "Regidron", there is a high risk of developing unpleasant symptoms.
Overdose symptoms
In the case of an excessively large amount of ingested solution or when using the drug in high concentrations, the risk of hypernatremia formation increases. The main manifestations of this pathological phenomenon are weakness, drowsiness, nervous and muscle excitement, coma, confusion, respiratory arrest.
In patients with impaired renal function, there is a likelihood of developing metabolic alkalosis, which is characterized by neuromuscular overexcitation, tetanic convulsions, and decreased lung ventilation. In addition, in this case, the development of hyperkalemia is possible.
With a pronounced overdose of a drug with vivid symptoms of metabolic alkalosis or hypernatremia, the drug should be stopped. Further therapy is prescribed based on laboratory tests and diagnostic results.
Special recommendations
Not everyone understands why take Regidron powder. If a person loses more than 10% of body weight in severe forms of dehydration (anuria), it is necessary to restore the appointment of intravenous infusions of drugs and rehydration drugs with the further use of the agent described by us.
Without confirmation through laboratory tests of the need for additional use of electrolytes, it is impossible to increase the recommended dosage regimen. A high concentration of the drug solution can provoke the development of hypernatremia. For vomiting and nausea, this medicine is recommended to be taken in small quantities chilled. It is forbidden to add sugar to the drug solution. You can eat immediately after successful rehydration.
What else does the instructions for use with Regidron powder tell us?
In case of poisoning, accompanied by vomiting, the drug should be taken after 10 minutes slowly, in small sips. With dehydration in people with diabetes mellitus, kidney failure, and other chronic diseases, monitoring their condition during drug therapy is required, since dehydration provokes a violation of electrolyte, acid-base or carbohydrate balance.
If there is loose stool with blood impurities, hyperthermia with high rates (more than 39 ° C), diarrhea lasting more than 5 days, abrupt cessation of diarrhea, the development of bright pain, cessation of urination, delayed speech in the patient, excessive fatigue, sudden drowsiness or inability to talk to the patient, it is urgent to consult a doctor.
With diarrhea that develops with cholera and other severe intestinal infections, the use of this solution in order to achieve electrolyte balance may not be enough.
Use in lactation and pregnancy
During pregnancy and during the lactation process in the recommended dosages, the use of "Rehydron" is allowed, but before that it is recommended to obtain the advice of a doctor.
Use in childhood
How to dilute "Rehydron" for a child is described in detail in the instructions. There are no age restrictions on the use of this medical device, therefore, it can be used at any age in the treatment of children.
For children in the first year of life, the initial dosage should not be more than 5-10 ml (volume of a teaspoon). Take a drug solution every 10 minutes. During the day, the baby should be given no more than 30-50 ml of the drug per 1 kg of body weight.
With indomitable vomiting in a child, it is recommended to wait out the attack and only after that give the drug. It is very important that the child does not immediately drink a large amount of solution, since excessive filling of the stomach provokes vomiting. It is necessary to water the child with the drug often, but in small doses - so the medicine will be absorbed faster in the digestive tract and have the necessary therapeutic effect.
In especially severe conditions, the child can be given "Regidron" in the calculation of 80-100 ml per 1 kg of body weight.
Drug interaction
How to drink "Rehydron" for adults and children with other medicines? Since the ready-made medical solution has a slightly alkaline reaction, it can in some way affect the effectiveness of medications, the absorption of which depends on the level of the acid-base balance of the intestine.
Shelf life of Regidron powder and finished solution
The drug in the form of a powder has a shelf life of 3 years. The prepared solution must be used within a day. After this time, it is considered unsuitable for admission.
Cost
The price of powder for oral administration "Regidron" varies from 15-20 rubles per bag. It depends on the region and the pharmacy network.
Analogs
Analogues of the medication are:
- "Hydrovit" is a medicine, which contains the following active elements: dextrose monohydrate, sodium chloride, potassium chloride, sodium hydrocytrate. This medication is used for diarrhea for electrolyte replacement and rehydration, as well as a prophylactic for electrolyte disorders resulting from severe sweating during hyperthermia or increased physical exertion.
- "Trihydron" is a pharmacological drug whose therapeutic effect is aimed at removing toxins from the body and replenishing in it the lost fluid lost as a result of vomiting or diarrhea during poisoning and other pathological conditions. This medication is produced in Russia, by the pharmaceutical company Marbiopharm. The powder contains substances such as potassium chloride, dextrose monohydrate, chloride and sodium citrate, has a high activity when penetrating into the intercellular space, rapidly leaving the vascular bed.
- “Citraglucosolan” is a medicine that is a combination of several basic substances: glucose, sodium chloride, sodium citrate and potassium chloride. This medication is indicated for those patients who need help with mild to moderate dehydration, which can be triggered by infectious diseases and their consequences, for example, diarrhea. The medicine should be prescribed for prophylaxis in order to avoid disorders of salt and water metabolism, as well as in the treatment of patients experiencing high physical exertion.
- "Reosolan" - an analogue of the "Rehydron", with an absolutely identical composition. This tool is used for electrolyte and water imbalance during dehydration (thirst, polyuria), diarrhea, heat damage, acidosis, intense sweating (physical and thermal stress).
Reviews
Most patients who used Regidron powders left positive feedback about him. They characterize this medication as a means that has been confirming its effectiveness and safety for many years. Many patients note that this remedy always pleases with its low cost and availability in almost every pharmacy.
As for the action of the drug "Regidron", it perfectly removes signs of dehydration. The drug is considered an indispensable tool in the treatment of a variety of poisonings (in particular food), when the patient experiences vomiting and diarrhea. The powder is easily diluted with water, that is, the method of its preparation is convenient and simple. The taste of the finished solution is slightly salty. Patients note that the medicine does not have an odor, therefore, with nausea it is not difficult to take it. If you know what the Rehydron powder is taken for, the effect will be, but it is not achieved immediately, after about a few hours.
Negative reviews are few, but they contain information that this drug causes some adverse reactions, in particular - allergic manifestations on the skin, a violation of the digestion of food. Doctors note that this medication does not contribute to the occurrence of disorders in the digestive tract, and such symptoms appear most likely due to other pathological conditions and causative factors. According to medical experts, “Regidron” today is the main drug, which absolutely safely affects all body systems, quickly eliminating the clinical signs of dehydration without harm to health.
The reviews also indicate that this medicine is well tolerated by children, adverse reactions to it are extremely rare. When using it in childhood, it is very important to follow the dosage regimen and the rules of admission.
We examined why to take Regidron powder.