During pregnancy, "Flucostat" is used quite often. However, many experts argue that the appointment of such a drug during gestation is extremely dangerous.
So is it possible to take "Flucostat" during pregnancy? We will answer this question in the materials of this article.
Basic information
Thrush, or so-called candidiasis, is a fairly common disease that occurs in women in an "interesting" position. The causative agent of this disease is a fungus of the genus Candida. In the normal state of the immune system, it does not cause any discomfort to the fairer sex. However, with a decrease in immunity, as well as with improper nutrition, chronic diseases and an imbalance of hormones, this microorganism begins uncontrolled reproduction, which ultimately causes the development of unpleasant symptoms.
Before answering the question of whether Flucostat can be used during pregnancy, it should be told that such a disease is manifested by cheesy discharge and severe itching in the genital area. During the bearing of the fetus, this disease carries a special danger. She poses a threat not only to the expectant mother, but also significantly increases the risk of infection of the baby during childbirth.
Thus, it should be noted that candidiasis in pregnant women requires mandatory treatment. In this case, preparations from thrush should be selected only by an experienced doctor.
Features of the medication
What makes Flucostat remarkable? Instructions for use (the price of the drug is indicated below) states that this drug is an active antifungal medication that has a systemic effect. Its active elements are able to penetrate into all organs, tissues and show up in them for a long time. In addition to the fungus of the genus Candida, this tool effectively destroys coccidioid and creptococcal microflora.
The mechanism of action of the drug in question is aimed at inhibiting the enzymes of fungi, due to which they very soon cease to multiply. At the same time, already existing colonies quickly die on their own, and also do not spread to other organs.
Pregnancy
So can Flucostat be used during pregnancy? To treat candidiasis during gestation, specialists select the most sparing drugs that do not have pronounced toxic effects. Therefore, the drug in question is used only in exceptional and rare cases, including with a generalized form of thrush.
As you know, analogues of this medication are drugs such as Diflucan, Futsis, Fluconazole and Mikosist. All of them are contraindicated for use not only during pregnancy, but also during breastfeeding. This is due to the fact that their main ingredients quite easily penetrate into all fluids and tissues, as well as overcome the placental barrier.
If you still decide to use Flucostat during pregnancy, then you should know that fluconazole, that is, the active substance of this medication, negatively affects not only the fungal flora, but also represents a toxic substance that disrupts internal processes and is harmful on fetal development.
Indications of the drug when bearing a child
Can Flucostat be used during pregnancy? 1st trimester, as, however, the 2nd and 3rd, is not the period when you can use this tool. However, there are exceptional cases in which the use of potent drugs is still permissible.
Sometimes in the body of a future woman in labor, conditions are created that favor an extensive fungal spread, as a result of which such a disease covers almost the entire female body. According to experts, in 75% of cases, such a generalized lesion is fatal. In this case, even ordinary thrush in the vagina or on the oral mucosa can suddenly go into a systemic fungal disease. As you know, this pathological process is promoted by diseases that reduce immunity, including HIV infection, leukemia and diabetes mellitus.
So in what cases can Flucostat medication be used during gestation? Suppositories during pregnancy and other forms of this drug are allowed to be used if there is a serious threat to the woman's life. In this case, the health and condition of the fetus go by the wayside.
Contraindications
Is it possible to prescribe Flucostat during pregnancy? 3 trimester - this is the time when this drug is not recommended for use, as during the first two trimesters.
For a long time in the United States, a special list of drugs that are dangerous when bearing a fetus has been developed. At the same time, six categories of pharmaceuticals were identified. “Flucostat” (any form) belongs to category C, which includes medicines that, during clinical trials, have shown their detrimental effect on fetal development in experimental animals.
Of course, due to ethical considerations, such experiments cannot be carried out on pregnant women, however, the similarity of internal physiological processes between animals and humans indicates a greater likelihood of a negative effect of fluconazole on the development of an unborn child. For this reason, "Flucostat" is almost never prescribed for the treatment of pregnant women. If necessary, doctors recommend the use of other antimycotic drugs that are not able to affect the fetus in a destructive way.
Side effects on the fetus
Now you know about the effect of Flucostat on the body of a future mother in labor.
Instructions for use (the price of this tool is about 200-250 rubles per 1 capsule) states that no experiments were conducted to confirm the detrimental effect of the drug in question on pregnant women. However, it should be noted that at present there is information about babies whose mothers have long used this drug uncontrollably for the treatment of candidiasis. In such children, birth defects were discovered due to the embryotoxic and teratogenic effects of the drug.
Thus, we can safely conclude that taking about 400 mg of fluconazole per day can negatively affect the development of the fetus.
Side effects in pregnant women
Standard adverse reactions that occur in response to taking fluconazole in expectant mothers can be the following:
- Heart rhythm disturbance.
- Change in taste, nausea, dyspepsia.
- Headaches, dizziness, cramps.
- Yellowing of the skin, sclera.
- Allergic reactions.
The drug "Flucostat": the first week of pregnancy, planning
The medication in question has such properties, due to which the removal of its active substance from the body is very long. At the same time, experts say that even after 6 months during the analysis, fluconazole residues are detected in almost all patients.
Thus, treatment with "Flucostat" should be carried out long before the start of the pregnancy planning period or replace it with a more gentle drug.
According to the instructions, taking fluconazole-based drugs in the first days and weeks of pregnancy can contribute to the development of heart defects in the unborn baby. This is due to the fact that at the beginning of the first trimester, all vital organs, including the cardiovascular system, are laid in the fetus.
Some statistics
As practice shows, in women who used the drug "Flucostat" during pregnancy, the frequency of birth of babies with heart defects was observed several times more often than in other women in childbirth. Also, increased doses of this medication can provoke the development of birth defects in children, including pathology of the musculoskeletal system and in the maxillofacial region.