In the article, we will figure out why Unidox Solutab tablets help.
The pharmacological drug is produced on the basis of the active substance - doxycycline, which is a representative of tetracycline antibiotics. Doxycycline has bacteriostatic properties due to inhibition of the production and disruption of protein metabolism, which are contained in the cell membrane of pathological microorganisms.
In addition, this medicinal product disrupts the connection of certain types of RNA with ribosome membranes and is characterized by rather high activity to cultures of microorganisms that are in the functional stage of division and growth, while the drug has practically no effect on microorganisms that are at rest.
Composition and form of release
According to the instructions for Unidox Solutab, the clinical and pharmacological category of this drug is an antibiotic of the tetracycline class.
The active element of the medication is doxycycline monohydrate, which is supplemented with lactose monohydrate, microcrystalline cellulose, colloidal anhydrous silica, saccharin, low-substituted hyprolose, hypromellose and magnesium stearate.
The medicine is available in the form of tablets that dissolve in the oral cavity and require swallowing. The form of the tablets is round, biconvex, the color is light yellow, with a shade of gray. On one side there is a code label 173 and dividing risk - on the other. In addition, the drug is made in the form of solutions for intravenous administration. Unidox Solutab is not available in the form of candles.
Indications for appointment
As the instruction indicates, "Unidox Solutab" is prescribed for numerous infectious diseases, which include:
- Genitourinary system pathologies in the form of cystitis, endometritis, urethritis, gonorrhea, bacterial prostatitis, pyelonephritis, syphilis, chlamydial infection, urogenital mycoplasmosis. "Unidox Solutab" with prostatitis is now prescribed most often.
- Digestive and biliary tract diseases in the form of dysentery, cholecystitis, gastroenterocolitis, travelers' diarrhea, cholera, yersiniosis, cholangitis.
- Diseases of the ENT organs and respiratory system in the form of acute bronchitis, tracheitis, pneumonia, pharyngitis, tonsillitis, otitis media, sinusitis, lung abscesses.
Unidox Solutab also has the following indications for use: pathologies in the form of eye infections, sepsis, osteomyelitis, infections resulting from animal or insect bites, chlamydia, pertussis, typhoid, proctitis, Lyme disease, plague, malaria, ornithosis, bartonellosis, psittacosis , brucellosis, peritonitis, infections of soft tissues and skin.
Method of use and dosage of medication
In accordance with the instructions to Unidox Solutab, the duration of administration and dosage of this medical product should be determined by the doctor, depending on the type of pathological process and the features of its course. Capsules are swallowed whole, or crushed and mixed with water, tablets are intended for absorption in the mouth. It is preferable to take this medicine with meals while sitting or standing, which reduces the likelihood of developing an esophageal ulcer and esophagitis. Medication is not recommended before bedtime.
What is the dosage of Unidox Solutab? Adults and children after 8 years of age weighing more than 50 kg are prescribed 200 mg / day on the first day of therapy, and 100 mg / day on the following days. In case of development of severe infectious processes, 200 mg / day is prescribed throughout the entire therapeutic course.
For children of 8-12 years old weighing less than 50 kg, the daily dosage is 4 mg / kg on the first day, then 2 mg / kg / day. In cases of severe illness, this medication is prescribed in a dosage of 4 mg / kg during the entire period of therapy.
How to take "Unidox Solutab" in gynecology?
In uncomplicated gonorrhea (except for anorectal infections), 100 mg is prescribed 2 times / day until absolute cure (approximately 7 days).
With urogenital infectious pathologies provoked by Chlamydia trachomatis, non-gonococcal urethritis, cervicitis provoked by Ureaplasma urealiticum, 100 mg 2 times / day is prescribed for 7 days.
Use for prostatitis
Antibiotics of the tetracycline group are widely used to eliminate the inflammatory process in the prostate gland. They act on the proteins of microbes and destroy them. This medication affects a wide range of bacteria that cause prostatitis.
According to the instructions, “Unidox Solutab” is prescribed in the presence of acute and chronic prostatitis caused by infectious lesions of organs located in the pelvis. The antibiotic does not eliminate the symptoms of the disease, but acts on the very cause of its occurrence - microorganisms that provoked prostatitis. Therefore, the abacterial forms of this pathological process with the help of this drug cannot be cured.
This antibiotic can be used when penetrating the prostate infections transmitted through the genital tract. He actively fights prostatitis pathogens, such as gonorrhea, ureaplasma, chlamydia, which become the most common cause of the development of inflammatory processes in the prostate gland. Therapy with this medication can be prescribed if pathogenic bacteria have spread from infected organs and systems to the prostate.
Gynecological practice
The purpose of the drug "Unidox Solutab" today is widespread in gynecology, in the treatment of numerous inflammatory processes in the female genital area, which are caused by infectious agents that are sensitive to this pharmacological drug. These include a variety of inflammations - the bodies of the uterus, fallopian tubes, ovaries, cervix, etc. Sexual infections that penetrate through the vagina during unprotected intercourse are treated with this medicine.
In addition, they prescribe Unidox Solutab during the passage of infection from the reproductive sphere to urological organs - the bladder (cystitis), the urethra (urethritis). These inflammatory processes are also very successfully treated with this medication.
Contraindications
This pharmaceutical agent can not be used in the following pathological conditions:
- severe violations in the liver and kidneys;
- pregnancy, lactation;
- allergic phenomena in the treatment of antibacterial agents from the category of tetracyclines;
- porphyria;
- age up to 12 years.
Side effects of Unidox Solutab
Against the background of the use of this medication, some adverse reactions may occur, including:
- Allergic: urticaria, exacerbation of lupus erythematosus, anaphylactic reactions, pericarditis, angioedema, erythema multiforme.
- Phenomena from the central nervous system: increased intracranial pressure (cephalalgia, swelling of the optic nerve, vomiting), vestibular disorders (dizziness), bifurcation in the eyes, blurred vision.
- Phenomenon of the skin: exfoliative dermatitis, erythematous and maculopapular rash, photosensitivity.
- Circulatory system: decreased prothrombin activity, hemolytic anemia, thrombocytopenia, eosinophilia, neutropenia.
- Endocrine system: in patients who have received this medication for a long time, a reversible staining of the thyroid tissue in brown may be observed.
- Digestive organs: dyspepsia, diarrhea, anorexia, dysphagia, enterocolitis, pseudomembranous colitis, esophageal ulcer, darkening of the tongue, esophagitis, liver damage (with prolonged use or in patients with liver and kidney failure), cholestasis.
- Urinary system: an increase in the level of residual urea nitrogen (due to anti-anabolic effects).
- Musculoskeletal system: doxycycline can disrupt the formation of teeth in children, change their shade (enamel hypoplasia).
- Other phenomena: candidiasis, vaginitis, stomatitis, proctitis.
Side effects of Unidox Solutab are described in detail in the instructions.
Pregnancy and lactation
The medicine is not used during pregnancy, except in situations where this medical product is the only one for therapy in extremely dangerous and severe infectious processes (for example, spotted fever, exposure to Bacillus anthracis and others).
The active substance of this pharmacological drug passes into breast milk and, due to adverse effects on the fetus, like other tetracyclines, is not used during breastfeeding. In cases where the appointment of such medications is necessary, the lactation process should be discontinued.
Combination with alcohol
Can I take Unidox Solutab and alcohol at the same time? With the simultaneous use of a medicinal product and alcoholic beverages, their toxic effects on the liver and digestive system are significantly increased, which can lead to toxic hepatitis. In addition, the therapeutic effect of taking the drug is reduced. Drinking is possible only seven to ten days after the end of the medication.
Do not mix Unidox Solutab and alcohol.
Overdose symptoms
With a significant increase in the dosage of the drug, severe nausea, vomiting, hyperthermia, yellowness of the skin, bleeding can occur. If such symptoms are observed, gastric lavage, administration of enterosorbents and laxatives are necessary. Also, the patient is shown a plentiful drink. Analogs of Unidox Solutab will be considered below.
Drug interaction
The drug reduces the bioavailability of antacids - drugs that contain calcium, magnesium, cholestyramine, aluminum, sodium bicarbonate. There must be a break of at least 1 hour between taking this antibacterial drug and the above substances.
The absorption of both drugs is disturbed while taking an antibiotic with iron preparations. Phenytoin, barbiturates and carbamazepine enhance the decomposition of doxycycline in the liver and reduce its concentration in the blood, as a result of which dosage adjustments of the Unidox Solutab drug may be required. It can enhance the therapeutic effect of indirect coagulants with concomitant use. At the same time, prothrombin time monitoring is necessary. The risk of a pseudotumor of the brain increases when using drugs with vitamin A content while taking the Unidox Solutab medication. During treatment, it is also necessary to take into account the decrease in the effectiveness of oral contraceptive estrogen-containing agents.
Special recommendations
This medicine should be taken orally in a standing position, washed down with water, which will prevent damage to the esophagus and irritation of the mucous membranes of the digestive organs. During the therapeutic course, it is necessary to exclude exposure to the sun. This tool can be prescribed to patients with renal failure, since it is excreted exclusively through the gastrointestinal tract.
Analogs of Unidox Solutab
The most common analogues of this pharmacological drug are:
- "Vibramycin D";
- doxycycline hydrochloride;
- Doxybene
- tetracycline hydrochloride ;
- "Doxycycline";
- Doxa-m-ratiopharm;
- Tigacyl.
Reviews on this drug
Quite a lot of reviews about Unidox Solutab, however, among them there are both positive and negative. One part of patients consider it a very good antibacterial drug that fights complex inflammatory processes. They claim that the medication helped them quickly cope with the disease and recover.
Other patients note that, despite the effectiveness, they refused to use this medication due to the numerous adverse reactions that it causes. Among them, the most pronounced were observed - severe nausea, diarrhea, dehydration, and fever. Many of them believe that the therapeutic effect of taking the drug is disproportionate to those negative phenomena that occur as adverse reactions.
Reviews about Unidox Solutab from experts suggest that this medication can be considered highly effective, despite the fact that the substance present in its composition has been produced in the form of other medicines for a very long time and has existed for several decades. However, doctors do not recommend independently treating inflammatory diseases, you should contact a specialist for a properly organized treatment regimen and selection of individual dosages. This will help to avoid the development of an overdose and the negative impact of the pharmacological agent on the body.
We figured out why Unidox Solutab tablets are prescribed.