In the article, we consider the instructions for use and reviews for the Blemaren drug. It is a drug intended for the treatment of nephrolysis. This disease is accompanied by the formation of stones in the organs of the urinary system. The main therapeutic effect of Blemaren is aimed at the dissolution of crystals of mineral salts of small size.
The composition of this drug
According to the instructions for use, Blemaren is made in the form of soluble, effervescent tablets intended for oral administration. One tablet contains several active ingredients, including:
- Citric acid
- Potassium bicarbonate.
- Sodium citrate.
In addition, the composition of the tablets is supplemented by a number of auxiliary components, such as mannitol, macrogol, lactose monohydrate, adipic acid, sodium saccharin, lemon flavor. The tablets are presented in a round form, have a white color and are packaged in packages of 20, 80 and 100 pieces. The preparation is equipped with detailed instructions for use with Blemaren tablets and test strips to detect increased acidity of urine.
Properties of the drug
Active components contribute to a change in the acid state of urine, causing its slight alkalization, that is, an increase in pH. This action of the drug causes a decrease in the rate of formation of salt crystals, uric acid and oxalates accompanying nephrolithiasis, otherwise called urolithiasis. “Blemaren”, among other things, reduces the excretion of dissolved calcium salts with urine, which helps prevent the formation of new formations.
According to the instructions for use, the drug "Blemaren" has one hundred percent bioavailability of the active components. After oral administration, the active substances are completely absorbed from the intestine, which allows them to reach their maximum concentration in the blood after half an hour. The components of the drug are excreted through the kidneys with urine, while they remain unchanged.
Indications for the use of the drug
What else can you learn from the instructions for use? "Blemaren" is intended to eliminate pathological processes that occur in the organs of the urinary system and are accompanied by the formation of salt crystals. The main therapeutic goals when using the drug are:
- Litholysis of calcium-oxalate-type formations, as well as the prevention of their occurrence against the background of an increased acid content in urine, as well as an increased level of calcium in its composition.
- Dissolution of stones of urate or urate-oxalate type.
- Litholysis of uric acid sediment against the background of an increased level of uric acid salts contained in urine.
- In combination with other drugs, "Blemaren" is used to treat porphyria of the skin, which is a violation of metabolic processes.
Taking this medication for prevention
In addition, "Blemaren" is prescribed for prophylactic purposes to prevent the formation of stones, namely calcium-oxalate and urine-oxalate varieties of them due to prolonged radiation or chemotherapy. These methods of treatment are accompanied by the death of many cells and an increased level of uric acid.
Contraindications to the use of the drug
Instructions for use "Blemaren" contains a number of restrictions. The drug is not prescribed for the following conditions and pathologies:
- Hypersensitivity or an individual reaction to the components that make up the drug.
- Metabolic alkalosis. It is a pathology that is accompanied by the occurrence of an alkaline reaction of urine and blood. "Blemaren" is able to aggravate the condition of a patient with this pathology.
- Kidney failure in acute or chronic forms of the course, accompanied by a complication of the formation of primary or secondary urine.
- Diseases of the organs of the urinary system caused by an infectious pathogen that breaks down lactic acid in the course of its life.
- Severe arterial hypertension, as well as other diseases, the treatment of which involves maintaining a salt-free diet.
- Urine pH above 7.0.
Also, the drug is not prescribed at the age of less than 12 years, since there are no studies on the safety of taking pills in this age group.
Instructions for use of the drug
"Blemaren" is taken orally after a meal. Before taking, the tablet is dissolved in a glass of liquid, it can be water, juice, mineral water or tea. It is allowed to take up to six tablets per day several times at regular intervals. The maximum dosage is determined by the doctor, based on indicators of the acid-base state of urine.
This confirms the instructions for use for the drug "Blemaren".
A correctly selected treatment regimen involves the following pH indicators in the composition of urine:
- 6.2 - 7 for the treatment of uric acid stones.
- 7.5 - 8.5 in the treatment of cystine-type formations.
- 7.2 - 7.5 with the complex treatment of porphyria.
- Less than 7 on the background of the use of radiation or chemotherapy.
The acidity of urine is checked using test strips, which change their color, showing the pH level. The color is compared with a special scale on the attached sample. On average, the course of treatment with Blemaren should be no more than 20 days.
Adverse reactions from the use of the drug
The instruction to "Blemaren" indicates that the reception may cause unwanted reactions, namely:
- An allergy accompanied by symptoms such as urticaria, itching, and skin rash. In rare cases, angioneurotic Quincke edema may develop, as well as an even more severe anaphylactic shock.
- Metabolic alkalosis. It is an alkaline reaction of blood and fluid in the intercellular space.
- Dyspepsia, accompanied by nausea and vomiting, soreness in the abdomen and flatulence.
- Swelling of the skin, localized on the eyelids and around the eyes as a result of sodium retention in the body.
If the patient discovers symptoms of adverse reactions, he should refuse to take the drug further and consult a doctor.
So it says in the instructions. Reviews about "Blemaren" are available in large numbers.
Overdose
A significant excess of the prescribed dosages can also lead to the development of adverse reactions from the body, which are manifested by the development of metabolic type alkalosis. This pathology gets especially strong severity against the background of existing renal dysfunction. If an overdose is detected, you should stop taking the drug and carry out intravenous administration of buffer solutions to bring the body pH back to normal.
In the instructions for use, the analogues of "Blemaren" are not indicated.
Analogs
There are a number of drugs that can be considered analogues of the drug. The most popular among them are:
- "Urolesan." It has a diuretic, antiseptic and antispasmodic effect. The main difference from the original is the ability to increase the acid level in urine.
- "Cystenal." Helps alleviate the natural release of small calculus. With the systematic administration of the drug, it converts stones to a state of sand.
- "Fitolizin". The effectiveness of the drug is due to the removal of urea from the body, as well as preventing the formation of kidney stones. In addition, “Fitolizin” has an anti-inflammatory effect. This tells us the instructions for the analogue of "Blemaren."
- "Uronefron." Promotes leaching of sand and small stones from the kidneys, and also prevents the crystallization of mineral salts.
- "K-Na hydrogen citrate" is able to increase urine alkalinity. The drug helps to dissolve the stones that arise in the urinary system and their further excretion with urine.
- Soluran. It is prescribed for urolithiasis. Promotes the transformation of kidney stones and their excretion with urine.
A rather popular question among patients about the differences between Blemaren and Uralit U. The composition of both drugs is quite similar, as well as properties. The release form differs for the preparations, “Uralit U” is produced in the form of a powder. It is believed that effervescent tablets are a more convenient form of the drug, since there is no need to adjust the desired dosage.
Cystenal
The drug tool "Cystenal" is a powerful diuretic (diuretic), anti-inflammatory and antispasmodic drug. It has a direct effect on smooth muscle and contributes to the destruction of renal calculi. The drug "Cystenal" is used to treat pathological disorders of the urinary system, including: crystalluria, urolithiasis, which is accompanied by secondary inflammatory changes and smooth muscle spasms of the urinary tract. The use of the medication is strictly contraindicated in chronic or acute form of glomerulonephritis, ulcerative lesions of the duodenum or stomach, renal failure, as well as in the case of the patient having various pathologies requiring surgical interventions.
Urolesan
The drug is plant-based. It has anti-inflammatory, antispasmodic and diuretic effects. It is prescribed for the treatment of urinary tract diseases. In syrup form, it can be used in childhood. Due to its natural composition rarely causes side effects.
We have reviewed the instructions for use with Blemaren. Doctors' reviews are also abundant.
Reviews
The medication is quite widely used in medical practice. Reviews about the effect of the drug on the part of patients are rather contradictory. Many believe that the drug has the proper therapeutic effect only in case of strict adherence to the treatment regimen. For some patients, the drug was prescribed based on high pH values. Moreover, the problem was completely eliminated only after the full course of treatment with Blemaren.
Experts consider the drug effective, but emphasize the complexity of the therapeutic regimen requiring detailed explanations. In addition, it is necessary to check the pH of urine before each dose, which significantly complicates the treatment itself. Another disadvantage, experts consider the high cost of the drug, reaching 1100 rubles per package.
Conclusion
In general, "Blemaren" is considered an effective drug for dissolving and removing stones. The main thing you should pay attention to is contraindications and strict adherence to the doctor’s instructions for treatment. It is strictly not recommended to independently try to get rid of stones through the drug, as this can lead to a lack of result or worsening of the condition.
The article was presented to "Blemaren" instructions for use and reviews.