In this article, instructions for use will be presented to the Penzital preparation. Price, reviews and analogues will also be considered.
A medication is an enzyme drug that belongs to a group of drugs that help normalize digestion. It is a combination of digestive substances that contribute to the digestion of food in the presence of certain pathologies of the digestive tract, which do not allow nutrients to be properly absorbed. The drug is manufactured by the pharmaceutical company SHREYA LIFE SCIENCES, Pvt. Ltd. Instructions for use with Penzital are very detailed.
The composition of the drug
The product is available in the form of tablets, top coated with a white enteric coating. The tablets are round, biconvex. The active substance of the drug is pancreatin, which has the activity of certain digestive enzymes - lipases, amylases and proteases. The activity of lipase is 6000 IU, amylase - 4500 IU, protease - 300 IU. The following components are used in the form of auxiliary elements in this medication:
- cellulose;
- lactose;
- sodium glycolate;
- starch;
- povidone;
- colloidal silicon dioxide;
- talc;
- methacrylic acid copolymer;
- titanium dioxide;
- diethyl phthalate.
Therapeutic properties
According to the instructions for use, Penzital is a set of enzyme substances that compensate for the insufficiency of the secretory work of the pancreas. This means that the drug can be used as a symptomatic treatment of any conditions that may be associated with insufficient digestion of food due to a lack of its own enzymes in the body, which must be produced by pancreatic cells. Enzymes in a drug make up for the lack of such enzymes. Lipase, amylase, trypsin, as well as chymotrypsin contribute to the processing of proteins from food into amino acids, fats into fatty acids and starch into dextrins, galactose, glucose and other monosaccharides.
This confirms the instructions for use for the Penzital tool. Price and reviews are listed below.
pharmachologic effect
The drug is used to normalize digestion and improve the functional ability of the digestive tract. As a result of taking the drug, nutrients are absorbed fully. The Penzital tablet passes from the stomach to the small intestine thanks to a special membrane that protects it from the effects of gastric juice. In the small intestine, it dissolves, and the enzymes contained inside are released and begin to help the body digest the incoming food.
Their maximum activity is observed approximately half an hour after taking the pill. One of the proteases, trypsin, stimulates the activity of the pancreas, forcing it to produce the necessary amount of its own enzymes. In addition, this substance gives a good analgesic effect.
Indications for use
In accordance with the instructions for use, Penzital is used to compensate for the digestive insufficiency that occurs with the following functional disorders and conditions:
- In chronic pancreatitis.
- After complete or partial removal of the pancreas.
- During radiation therapy and radiation exposure.
- With dyspepsia.
- In the presence of Remkheld’s syndrome (gastrocardial syndrome).
- With cystic fibrosis.
- With symptoms of flatulence.
- With non-infectious diarrhea.
- After partial or complete removal of the stomach.
- After removal of the small intestine or gall bladder.
- In the presence of inflammatory or dystrophic pathologies of the stomach, liver and gall bladder.
- In case of violations of the normal regime and the quality of nutrition (too fatty foods, irregular meals, too voluminous nutrition, etc.).
- With insufficient chewing (from lack of teeth, traumatic damage to the face, etc.).
- With a sedentary lifestyle and during periods of prolonged immobilization.
- During preparation for an ultrasound or x-ray examination of the digestive organs.
What else does the instructions for use with Penzital tell us?
Dosage and administration
Tablets should be taken with meals, not chopped, washed down with a small amount of liquid.
The dosage of this drug is set individually depending on what diseases caused a violation of the digestive process, as well as on the degree of their neglect.
The average dose of the drug is 1-2 tablets three times a day. In chronic forms of pancreatic insufficiency, as well as negative nutritional errors, the daily dosage should be at least 150,000 units of lipase, which corresponds to 25 tablets. Normally, in healthy people, this substance is produced in the amount of 400,000 units per day.
For children up to one and a half years old, the daily dose of a medication calculated on the basis of lipase activity should be, as a rule, 50,000 units. Older children are prescribed 100,000 units of lipase per day. The high activity of this substance can cause the development of constipation in children. Therefore, if necessary, therapy with high doses of this medication should begin with a small dosage, and gradually increase it, bringing the amount of substance to the necessary.
When establishing the dosage of a medical product, it should be borne in mind that the daily dose of active substances is 15,000 units. In addition, the amount of food consumed should be considered.
According to the instructions for use, Penzital tablets adults can drink for a long time.
The duration of the therapeutic course is determined by the variety of pathology, the degree of digestion. Thus, to eliminate the phenomena associated with errors in nutrition, as a rule, taking an average dose of pancreatin for several days is enough. In cases where enzyme preparations must be taken continuously to make up for the lack of natural enzymes, then treatment with this medication can continue for a very long time - up to several years.
What else is indicated in the instructions for use with Penzital tablets for adults and children?
special instructions
In the treatment of a disease such as cystic fibrosis, it is not recommended to use high doses of the drug, because this can lead to fibrous colonopathy in the ileocecal parts of the colon. For such patients, the daily dose, based on the activity of lipase, should be no more than 10,000 units per 1 kg of body weight. The use of the Penzital medical device for a long time determines the need for the use of iron preparations for preventive purposes. Experts do not recommend taking this medication during an exacerbation of pancreatitis.
In addition, the use of the drug is prescribed with caution to people who suffer from meconium ileus, or with lack of intestines, since a medication can contribute to the development of functional disorders of the digestive tract. This is described in the instructions for use of Penzital tablets.
Overdose symptoms
The phenomenon of drug overdose in children and adults often manifests itself in the form of constipation and increased concentrations of uric acid in urine and blood (hyperuricosuria and hyperuricemia). If such symptoms appear, discontinue therapy with this drug and eliminate constipation using symptomatic treatment methods, as well as reduce uric acid levels. No additional measures to eliminate the symptoms of an overdose are required. This is confirmed by the instructions for use. What helps Penzital, now we know.
Interaction with other medicines
The simultaneous use of medicines containing iron and the Penzital medication reduces the absorption of the former. And with concomitant antacid therapy, with the content of calcium carbonate or magnesium hydroxide - it leads to a decrease in the effectiveness of this medication.
Use during pregnancy and in childhood
The drug "Penzistal" is not contraindicated for these categories of patients, however, its use should strictly correspond to the indications. Consideration should also be given to the risk of its use, which should be less than the intended benefits. So tells us the instructions for use.
The price and analogues of Penzital are of interest to many. About it below.
Contraindications
You can not use this medication in the following cases:
- In acute pancreatitis.
- With exacerbation of the chronic form of pancreatitis.
- With high sensitivity to the components of the drug.
- The occurrence of allergic phenomena.
Side effects
According to the instructions for use and reviews of Penzital, the most common side effects from the use of the drug are symptoms that are associated with a disturbance in the normal digestive functions. These, as a rule, include nausea, constipation, diarrhea, discomfort in the stomach. Sometimes all kinds of allergic reactions can occur, as well as hyperuricemia and hyperuricosuria, in patients with cystic fibrosis - fibrous colonopathy.
We examined the Penzital medication instructions for use.
Analogs
In the modern pharmacological market, a wide variety of drugs of a similar enzymatic action are presented. These include:
- "Biozim".
- "Gastenorm forte."
- "Creon."
- Mezim Forte.
- Mikrazim.
- Panzinorm.
- Panzim Forte.
- "Pancreasim."
- Pancreatin-LekT.
- "Pankrenorm."
- Uni-Festal.
- Enzistal-P.
- "Pansitrat."
- The Hermitage.
- "Pangrol."
- "Abomin."
- "Pepsin K".
- Pepphiz.
- "Nygeda."
- "Normoenzyme."
- Normoenzyme forte.
- "Forestal."
- "Pancreoflat".
- Unienzyme.
- "Biofestal".
- "Festal".
- Enterosan.
In the instructions for use, the price of Penzital tablets is not indicated.
Cost
The cost of the drug is from 55 to 190 rubles. It depends on the region and the pharmacy network. Therefore, it is better to check the price with a pharmacist in advance.
Reviews
Most reviews of the drug are positive, and this is due to its effectiveness and low cost compared to other drugs in this group. People who used it to eliminate the symptoms of gastritis, overeating, heartburn and other problems, note that this drug was very effective.
Negative reviews about the drug are associated with its lack of effectiveness in some patients who have previously used other drugs in this group. This is due, according to experts, with the individual characteristics of the body.
There are also reviews left by parents of children who received the medicine in high doses, which led to irritation of the oral mucosa. In general, the drug is well tolerated and widely used for its intended purpose.
The article described in detail the preparation "Penzital" instructions for use, price, reviews and analogues.