Reviews, instructions for "Praziquantel" are of interest to many, since the drug is considered an effective tool to combat cestodes, trematodes. The medicine belongs to the third generation, which clearly shows its high effectiveness. The reviews of Praziquantel mention that this name was not patented, it is used internationally. In our country, you can buy tablets of the same name. The use of Praziquantel is effective in detecting worms in the body.
A lot of medicines with a similar active substance are on sale. Usually choose, evaluating the possible side effects and the concentration of the main compound.
When will it help?
Praziquantel and analogues can be used for infection with worms. The drug is effective for opisthorchiasis, clonorchiasis, schistosomiasis, hymenolepidosis, teniarinhosis, teniosis, paragonimiasis, diphyllobothriasis. When the active component enters the living tissue, the permeability of the cell membranes of the pathogens increases. This makes them more sensitive to calcium ions, stimulates muscle contraction and inhibits glucose transport. Such a chain of effects leads to a decrease in glycogen concentration, while lactic acid toxic for helminths is released. As can be seen from the instructions, Praziquantel quickly and effectively provokes the death of parasites.
Negative reactions
From the reviews, instructions for use of Praziquantel and analogues it is clear that drugs on such an active compound in some cases can provoke the occurrence of side effects. Statistics show that a negative result is observed only in 10% of cases and less. In some patients, the problem is associated with the functioning of the gastrointestinal tract - stomach pains worry, diarrhea develops. Possible headache, convulsive state, some are drawn to sleep. Cases of occurrence of febrile state, asthenia and allergy against the background of the use of Praziquantel have been recorded.
It is not always possible to say for sure the reason for the negative reaction of the body in taking the medication or is it a response to the mass death of parasites. It must be understood that the process is associated with intoxication of living tissues, which leads to a large load on the internal systems.
Application features
All the presented analogues of Praziquantel on the Russian market are drugs that can provoke adverse reactions. You can use them only under the supervision of the attending physician and under the direct instructions of the doctor. The effectiveness of the therapeutic program is determined by the particular case, parasites that infect the body, as well as the pattern of use of the medication and the doses that the patient needs to take. Only a professional can draw up a correct, effective therapeutic program, and the patient's task is to follow it steadily.
If the doctor recommended a specific drug, you can not change it to an analogue only because of a lower price. Replacement should always be agreed with your doctor. Otherwise, it is highly likely that the therapeutic program will not bring the desired effect.
"Biltricid"
Considering the analogues of Praziquantel, special attention needs to be paid to this drug. The drug is on sale represented by tablets intended for oral administration after food. Each tablet is coated with a thin film to simplify the administration procedure. Usually, several tablets are prescribed per day. Many doctors recommend combining Biltricid with vitamin complexes and drugs that improve liver function. It will not be superfluous to take medications to normalize the digestive tract.
One tablet of the effective analogue of Praziquantel Biltricide contains 600 mg of the active ingredient and several excipients, which include starch, cellulose, magnesium stearate and other compounds. Praziquantel in the patient's blood in the highest concentration is observed after an hour and a half from the moment the tablet was ingested.
Features of use
"Biltricid" is an analogue of "Praziquantel" for people, it is not recommended to use it for animals, even if infection with worms of a pet is supposed. The drug can not be used for children under the age of four. It is prohibited for pregnant women in the first three months of gestation. If a woman is breast-feeding a baby, it is necessary to replace the drug with another or refuse lactation. Biltricid is not suitable for patients undergoing anticonvulsant therapy and containing rifampicin. The cost of one package is up to 400 rubles.
Azinox
The analogue of Praziquantel Azinox is a preparation produced in the form of tablets coated with a thin film. This tool is also suitable for the treatment of animals and has been widely used in veterinary practice. On sale are packages containing 10-30 tablets, each of which is 300 mg of the active component and additional compounds that simplify digestibility.
At a low concentration of the active compound, the drug affects helminths, provoking excessive muscle activity leading to death, and at a high dose it negatively affects the outer cover of worms. Features of admission are determined by the age of the patient, the specifics of infection. You can not use "Azinoks" simultaneously with medicines containing dexamethasone, as well as other drugs from the group of corticosteroids, since they inhibit the anthelmintic, the concentration of the active substance in the blood decreases. The analogue of Praziquantel Azinox costs on average 400 rubles. The price depends on the number of tablets in the package.
Cysticide
The tablets are intended for oral use. They can not be chewed, and for better digestibility, you need to drink plenty of water. Typically, the drug is prescribed a ten-day therapeutic course, using it three times daily. The manufacturer recommends that when undergoing such treatment, abandon physical activity and, if possible, avoid tasks that require increased concentration of attention. Do not drive.
One tablet contains 500 mg of the active ingredient. The medication is registered as a representative of a group effective in intestinal helminthiases.
Is it worth taking?
Currently, preparations containing praziquantel as the main substance are considered the safest for humans and effective in infecting worms. Means show a good result with a variety of pathogens. It is important to strictly adhere to the doses recommended by a specialist in order to reduce the likelihood of a side effect. As can be seen from the reviews, many patients did not at all encounter negative reactions of the body, since they precisely followed the doctor's instructions. In a pharmacy, you can choose a drug suitable for yourself from all means in which praziquantel is indicated as the active compound. Drugs differ in the concentration of this compound, price and manufacturer. At the same time, you should not replace the product yourself without consulting a doctor.
When can not be used?
The list of contraindications for drugs based on praziquantel is relatively narrow. Above have been indicated restrictions for pregnant women. In addition, funds with such an active substance should not be used if severe injuries, liver dysfunction are observed, and an increased susceptibility of the patient to the main active substance or any other substance included in the selected preparation is known. Means containing praziquantel can not be used if an eye disease is diagnosed - cysticercosis.
Neurocysticercosis: some features
If a preparation containing praziquantel is used to eliminate such a diagnosis, it must be understood: treatment is associated with a risk of fever and intracranial pressure. Some patients experience malfunctioning of thought processes, there is a risk of manifestation of the phenomena of meningism.
Bearing a fetus: or is it still possible?
In some cases, the doctor may advise the future mother in labor to use preparations containing praziquantel if infection with worms is detected. This is permissible only in the second and third trimester. Previously, the specialist weighs the possible risks and complications for the fetus, compares it with the likely benefits for women's health, and, on the basis of the collected analytics, decides on how justified the use of the medication containing praziquantel will be. A woman should be aware of all the risks associated with the use of the drug in order to take a therapeutic course consciously.
Breastfeeding and Praziquantel
Tablets from worms should be used very carefully when detecting infection by a breast-feeding woman. As a rule, lactation is temporarily suspended. You can not breast-feed while using praziquantel tablets, as well as the next 72 hours. This is due to the ability of the active substance to penetrate into breast milk - the concentration is four times less than in blood plasma, but this can have a negative effect on a small child.
Special occasion
Very carefully, Praziquantel and all analogues built on the same active substance should be used if the history contains a mention of hepatic impairment. If such a disease is currently observed, it is necessary to pay the doctor's attention to this fact. It may be possible to choose a more gentle treatment or additionally start taking medications to support the liver.
If cysticercosis of the ocular system is detected, preparations containing praziquantel cannot be used, since damage to the tissues of the visual organs caused by the death of parasites can develop. If a therapeutic course is prescribed for a patient with cerebral cysticercosis, hospitalization will be an obligatory stage of treatment.