It is rare when a pregnant woman manages to avoid health problems during such a crucial period. To maintain a normal state, you often have to take various drugs. One of the means that you have to use during pregnancy is Clexane. Assign it if necessary antiplatelet therapy and only under the strict supervision of a specialist.
Drug description
For the treatment and prevention of blood clots, Kleksan is used, which belongs to the group of anticoagulants. A medicine is used in traumatology, surgery, orthopedics. The active component of the drug - enoxaparin sodium - has an antithrombotic effect, dilutes the blood and is a derivative of low molecular weight heparin. During pregnancy, "Clexane" is prescribed with caution and in small doses, which does not affect the duration of bleeding.
The drug is a liquid (colorless or pale yellow) for injection, which is released in special syringes. Various dosages of the active ingredient are available: 2000, 4000, 6000, 8000 and 10,000 anti-XA ME in one syringe. There are two doses of the drug in the package.
Indications for use
Injections are prescribed for the treatment of the following pathological conditions:
- Deep vein thrombosis.
- Vein embolism after surgery.
- Prevention of the formation of blood clots and embolism in individuals who have been lying for a long time.
- Hemodialysis patients for the prevention of clot formation (if the procedure lasts no more than 4 hours).
- Angina pectoris and myocardial infarction.
The use of "Clexane" during pregnancy
According to the manufacturer’s official instructions, the use of an anticoagulant during the period of gestation is possible only as a last resort if the benefit to the mother outweighs the risk of complications for the fetus. In fact, the practice of prescribing a drug for women in the situation exists, and it is quite successful. Despite this, specialists are obliged to warn patients of an insufficient number of studies regarding the effect of the active substance on fetal development.
Most doctors prescribe Kleksan injections from pregnancy only from the 2nd trimester. For prevention, the medicine is used at a later date. Without the advice of a specialist, you should not use an anticoagulant to thin the blood in order to avoid serious consequences.
The main purpose of the drug during pregnancy is the prevention of deep vein thrombosis located in the pelvis, groin and legs. Due to the particular position, it is these veins that suffer most often.
Are there any contraindications?
Among the main contraindications to the use of the drug are the threat of bleeding associated with termination of pregnancy, hemorrhagic stroke of the brain, aneurysm, and an ulcer of the gastrointestinal tract during an exacerbation. Also, the following pathologies and factors include contraindications:
- Intolerance to the components of the drug.
- A history of cerebral ischemic stroke.
- Arterial hypertension.
- Age to 18 years.
- Diabetes.
- Recent birth.
- Various pathologies associated with impaired hemostasis.
- Open wounds.
- Active tuberculosis.
- Severe respiratory diseases.
- Pericarditis.
- The presence of malignant tumors in the body.
- Excess weight.
- Renal (hepatic) failure.
- The presence of intrauterine contraception.
How to calculate the dosage?
It is difficult to independently determine the required amount of medication for treatment or prevention. The dosage is calculated only by the doctor, individually for each case. For women in position, the daily dose may be 20-40 mg. The duration of therapy depends on the severity of the patient's condition. Usually, noticeable improvements appear within 7-10 days. Sometimes therapy is extended to 14 days.
If blood clot prophylaxis is necessary before surgery, it is indicated that the patient should be given a single dose of 20 or 40 mg of the drug (depending on the condition). The first injection is done 2 hours before surgery. When treating a heart attack, the dosage of the drug is calculated relative to the weight of the patient.
"Clexane" during pregnancy: how to prick?
The drug is made only in the form of a solution for subcutaneous administration. Therefore, in the absence of experience, the first injection should be carried out in a medical institution. According to the instructions, an injection must be done in the side of the abdomen. To obtain a positive result of therapy, you should adhere to the rules of the administration of the drug "Clexane" during pregnancy. Reviews of women confirm the effectiveness of the drug, subject to all recommendations.
First of all, you need to prepare a place for an injection. A woman should take a lying position, grab a fold of skin on the lateral surface of the abdomen and fully insert the needle (strictly upright). It is possible to unclench a crease only after the preparation is completely entered.
Many pregnant women fear this manipulation, but in fact there should be no reason for worries. In the treatment room, polyclinics should instruct the expectant mother and show how to choose the right place for the injection and make an injection. After the manipulation, the injection site is forbidden to rub, massage.
Side effects
The anticoagulant during pregnancy "Clexane" is used exclusively according to the indications and under the supervision of the attending physician, because the drug significantly increases the risk of bleeding. At the slightest suspicion of the development of such a pathological condition, you should immediately cancel the treatment with the drug and contact a medical institution.
In some cases, the development of thrombocytopenia in the first days of treatment with an anticoagulant was recorded. Most often, pain occurs at the injection sites, hematomas, seals, swelling are formed. An allergic reaction sometimes manifests itself in the form of a skin rash, redness. If any adverse reaction of the body to the administration of enoxaparin sodium occurs, consult a specialist.
Reviews
Many women are forced to start antiplatelet therapy before pregnancy and continue treatment throughout the gestation period. “Clexane” is often prescribed during pregnancy, and most expectant mothers leave positive reviews about the remedy. The disadvantages of therapy include only the appearance of bruises, swelling at the injection site.
The doctor may also advise a cheaper analogue of the medicine. During pregnancy, “Clexane” is recommended to be prescribed in lower doses and for a short course of treatment, be sure to take breaks of at least 7 days between them. If a severe allergic reaction and other serious complications occur, the use of an anticoagulant should be discarded.