"Neovir" is an immunostimulating drug that has antiviral activity against DNA and RNA genomic viruses. The activity of the drug is due to its ability to cause the formation of high concentrations of endogenous interferons.
Composition and release form of the Neovir preparation: The instruction describes the medicine in the form of a clear solution with a greenish-yellow color for i / m injection. In 1 ampoule of the drug, in 2 cm3 of the solution contains the active substance sodium oxodihydroacridinyl acetate, in an amount of 250 mg, and additional substances in the composition: sodium citrate, citric acid, water d / and.
Pharmaceutical action of Neovir solution: The manual defines the drug as an immunostimulating agent that has activity against DNA and RNA genomic viruses, including chlamydia and HIV pathogens. The effect of the drug is based on its ability to optimize the formation of significant concentrations of endogenous interferons in the body, including interferon alfa. The drug "Neovir" promotes activation of stem cells in the bone marrow, T-lymphocytes and macrophages. It has immunomodulatory activity, normalizes the ratio of subpopulations of T-helpers and T-suppressors. For some diseases, the drug "Neovir", the instruction indicates that it reduces the body's production of substances of tumor necrosis and activates killer cells. To a large extent, it causes an increase in the activity of polymorphonuclear leukocytes. In the presence of HIV infection, the Neovir preparation acts immunomodulatory: the absorption capacity of blood serum increases, the activity of leukocytes in the synthesis of interferon alpha increases, and the production of active oxygen compounds by phagocytes is stimulated. The highest activity of interferons in the body is achieved after 2-3.5 hours after injection of Neovir and lasts 16-20 hours.
Indications for use of the drug "Neovir": The instruction provides for the use of the drug as an immunostimulating agent as part of a combination treatment for: prevention and treatment of influenza and other acute respiratory viral infections (including in the presence of immunodeficiency states); infections caused by herpes virus type 1 and 2, Varicella zoster virus; cytomegalovirus infection in people with immunodeficiency; radiation immunodeficiency; treating HIV infection; encephalitis and encephalomyelitis of viral etiology; acute and chronic hepatitis B and C; urethritis, epididymitis, prostatitis, cervicitis and salpingitis of chlamydial etiology; venereal lymphogranuloma; oncological diseases; multiple sclerosis; candidiasis of the skin, mucous membrane.
Methods of administration of the drug "Neovir": Instructions for use prescribes a solution to be administered in oil , 250 mg (1 amp.). If necessary, a single dose of Neovir can be increased to 500 mg (0.5 g).
The course of treatment with Neovir is injections: It usually consists of 5-7 IM injections with an interval of 48 hours. The dose is determined by the clinical picture. The duration of the course of therapy is 8-12 days. With prolonged and preventive use, the interval between injections should be 3-7 days.
In the treatment of HIV infection, the drug "Neovir" is used in combination treatment. The course of therapy includes 10 i / m injections of 250 mg, with an interval between them - 48 hours. After the course, a break of 2 months is necessary. You can repeat the courses unlimited.
Side effects: In the form of general reactions (subfebrile temperature, allergic reactions). In the form of local reactions - local rapidly passing soreness at the injection site.
Contraindications: Do not prescribe for: severe renal failure; autoimmune diseases; pregnancy lactation (breastfeeding); children's age; hypersensitivity to the components of the drug. Requires careful use in the elderly.
Special instructions: If the drug is poorly tolerated or the injection site is painful, it is recommended to give an injection together with a solution of novocaine.
Overdose: There is no evidence of an overdose.
Interaction: Clinical studies and practice have not established the incompatibility or effect of the drug "Neovir" when used together with other drugs.