"Regidron" is a drug that belongs to the pharmacological category of medicines taken for rehydration and to reduce the severity of intoxication in the body. This medicine is used orally in the form of solutions in cases of dehydration and intoxication of various origin. What helps "Rehydron", interesting to many.
Composition and release forms
The medication is made in powders for the preparation of oral solutions. It has a crystalline structure and white color. The finished solution is a colorless liquid, odorless. The composition of the drug includes several basic active elements, which include:
- sodium chloride - in one sachet - 59.9 mmol / l;
- potassium chloride - in one sachet - 33.5 mmol / l;
- sodium citrate - in one sachet - 11.2 mmol / l;
- dextrose - in one sachet - 55.5 mmol / l.
Medicinal powder is packaged in bags made of aluminum foil. A cardboard box contains 20 or 4 packets and instructions for using the medication.
Pharmacokinetics and pharmacodynamics
"Regidron" - a tool that contains in its composition the salts that are needed to restore energy and electrolyte balance in the cells of the body. It is used to correct acidosis (high acidity), impaired in cases of dehydration (during dehydration with loss of salts under the influence of various pathological factors). For the best assimilation of salts, the osmolarity of the drug and the concentration of sodium ions are slightly reduced, compared with potassium ions. The osmolarity of the finished solution of this medication is 260 mosm / l, and the pH is 8.3.
Data on pharmacokinetics (absorption of the main active elements in the blood, their distribution over the tissues, as well as metabolism and excretion) are currently lacking. This is confirmed by the instructions for use for "Rehydron". When vomiting, it is often prescribed.
Indications for use
The main clinical indication for the use of powder for the preparation of solutions is to restore the amount of liquid and the concentration of necessary salt in the human body, under various pathological conditions that are accompanied by dehydration.
The use of "Regidron" in adults is as effective as in children.
So, the indications include:
- acute diarrhea, leading to a pronounced loss of salts and water;
- thermal damage to the body;
- It is also used in the prevention of dehydration with significant physical exertion, as well as with general overheating of the body.
In addition, this medication is used to restore fluid during dehydration of mild (3-5% of the total body weight) and medium (6-10%) degree, which was triggered by diarrhea of various etiologies.
Features of use in children
"Regidron" is a drug whose main indications for use are intestinal disorders in children, which occur with such a dangerous symptom for babies as diarrhea. If diarrhea is accompanied by vomiting, dehydration in a child occurs much faster. This in no case should be allowed, since the loss of even a tenth of the water carries a great danger to the child's body.
The use of the medication for children of different ages is advisable in the following situations:
- with conditions of intestinal infection;
- with overheating of a child with increased sweating;
- with vomiting, which was the result of poisoning and other intoxications;
- with irritable bowel syndrome and dysbiosis;
- with diarrhea of any etiology, giving an average loss of fluid;
- with excessive physical exertion, provoking a strong separation of sweat.
According to the instructions for use, "Rehydron" in case of diarrhea is contraindicated in some cases. Limitations and contraindications are described further in the article.
Side effects that occur in children during treatment with the drug are vomiting, if the medical solution was drunk too quickly. The use of "Regidron" for vomiting is as follows: you need to drink the solution in small sips, gradually, in a cool form.
Contraindications
There are several absolute clinical contraindications to the appointment of the medicinal powder "Regidron". These include:
- impaired renal function with the development of their acute failure;
- diabetes mellitus (insulin-independent and insulin-dependent);
- unconsciousness (impossibility of oral medication);
- impaired patency in any part of the intestine;
- high sensitivity to any of the medicinal elements of the drug.
Before taking the solution, it is important to make sure that there are no such conditions. Consider the detailed instructions for using Regidron for vomiting and diarrhea.
Dosage and administration
Before use, the medication in the form of a powder should be dissolved in one liter of cool boiled water. The prepared solution is taken orally, regardless of the meal. To correct the water-salt state in case of diarrhea, a medication is taken in a volume of 100 ml every five minutes (adults).
What is the use of Regidron for children with vomiting? For small patients, the volume of the solution is 50 ml. If necessary, it is possible to administer the drug through nasogastric tubes for four hours.
With a mild degree of dehydration, the daily dosage is 50 ml per kilogram of patient weight, with an average degree of 100 ml. The dosage for maintenance therapy is 100 mg per kilogram of body weight. It is used until the cessation of the causative factors of dehydration, such as diarrhea, ceases. The instruction to "Rehydron" confirms this.
If thermal cramps occur, severe thirst, polyuria (excessive excretion of urine), the solution is taken in volumes of 500-900 ml for half an hour, in small portions. Subsequently, every 30 minutes, the same volume of the drug solution is taken, and this procedure is repeated until the pathological symptoms disappear and the condition normalizes.
Adverse reactions
"Regidron" is a safe tool, when used correctly, taking into account the recommended therapeutic dosages, side effects during treatment usually do not develop. Potentially, the occurrence of some allergic reactions.
special instructions
Before you start using this medication, you should carefully read the annotation to it. For maximum therapeutic effectiveness, as well as preventing the occurrence of negative complications, it is extremely important to pay attention to special instructions, which include the following:
- In severe and severe dehydration, when the body’s fluid loss is more than 10% of the total weight, taking this medication should be combined with the intravenous administration of any saline solutions.
- It is not recommended to exceed the recommended therapeutic dosages of the Regidron solution if the need for additional electrolytes into the body is not confirmed by laboratory tests.
- One packet of drug powder is dissolved in a liter of water, in case of dissolution in a smaller volume and obtaining a highly concentrated solution, symptoms of hypernatremia (increased concentration of sodium salts in the blood) may occur.
- Sugar cannot be added to the ready-made solution of the Regidron drug.
- In patients whose imbalance in water and electrolyte was triggered by the development of kidney failure or diabetes mellitus, against the background of the use of the drug, periodic monitoring of laboratory indicators of salt concentration should be carried out.
- According to the instructions, "Rehydron" when vomiting for children and adults should be taken repeatedly (after a few minutes) in small volumes.
- In cases of speech retardation, high fatigue, drowsiness, hyperthermia above 39 ° C, cessation of urination or with red urine, persistent diarrhea for more than five days, intense pain in the abdomen, you should seek medical help, since further therapy at home can provoke the development of serious complications.
- In recommended therapeutic dosages, this medication can be prescribed during pregnancy and lactation.
- The drug does not affect the functionality of the structures of the central nervous system, therefore, against the background of the intake of solutions, dangerous work (driving vehicles), associated with increased attention and speed of reactions, is possible. This is stated in the instructions for use. What helps "Regidron", we examined.
Overdose
When taking an increased volume or an excessively concentrated solution of the drug, symptoms of hypernatremia may occur, which is often accompanied by nervous and muscle overexcitation, excessive drowsiness, confusion, weakness. Cases of coma and respiratory arrest are not ruled out. In case of impaired renal function and inhibition of their functions against the background of an overdose, alkalosis may develop (increased alkalinity of the blood).
Overdose therapy is carried out only in a hospital setting. A variety of saline solutions are administered intravenously with monitoring of laboratory parameters.
Analogues of the drug
Analogs of this drug include:
- "Hydrovit" is a medicine that is used to treat dehydration in children. The active substances of the drug are potassium chloride, sodium, sodium hydrogen citrate, dextrose. The medication is used to replace electrolytes during loss of fluid, take it during diarrhea, overheating, increased sweating.
- "Reosolan" - a means by which you can replace "Regidron." It is available in the form of powders for reconstitution and oral administration in cases of imbalance in the water-electrolyte balance due to dehydration, diarrhea caused by cholera vibrio, heat damage, and intense sweating.
- “Glucosolan” is a medication that compensates for sodium, potassium salts, preventing dehydration in the body. This drug is produced in the form of tablets of two types. For each tablet of solan, which contains potassium, sodium chloride and sodium citrate, four tablets with glucose are used, which in total is 2 g of the substance. In addition, there is such a dosage form as powder bags.
- “Citraglucosolan” is a medicament close in composition to “Glucosolan”, however, glucose is not applied separately, but mixed with electrolytes. This medicine is produced in the form of powders soluble in liquids.
- “Trisol” is a pharmacological agent that serves to restore metabolism, normalize blood microcirculation, heart and kidney functions during the period of acute forms of dysentery, food intoxications, which provoke the development of dehydration. The release form of this medication is a solution for infusion.
The cost of the drug
The average price of 20 sachets of the Regidron medicinal product varies from 390-410 rubles. It depends on the region and the pharmacy network.
Reviews
Patients and specialists call this medication a first aid for dehydration. And this is no accident, since this medicine is one of the main ones used in general practice for diarrhea, vomiting, intoxication and poisoning.
Patient reviews about this drug are entirely positive and contain information about its high effectiveness. For example, most people who took it noted a significant improvement in their general well-being against the background of the above pathological conditions. Against the background of food poisoning, they decreased symptoms of chills and aching in the bones, muscle pain and other manifestations of acute lack of fluid in the body. In addition, patients observed that when using this medication they never had any adverse reactions, which indicates a good tolerability of this drug. During use in children, Regidron also established itself in the best possible way.
Doctors reviews
Experts do not just recommend this tool, they indicate that it is simply necessary for various symptoms of dehydration, since such a condition is very dangerous for the human body, and especially for children. In general, they respond positively to the medication.
We have reviewed the instructions for use for adults and children for the Regidron preparation.