👉🏻 🚻 🆘 "Chorionic gonadotropin": instructions for use, analogues and reviews 🌭 🤗 🌧️

The term "human chorionic gonadotropin" refers to a hormonal substance that can be detected in the female placenta. In the blood of males it is also present, but in scanty concentrations. Currently, the pharmaceutical market produces a drug under the trade name "Chorionic gonadotropin." It is a lyophilisate for solution for injection. As a rule, the drug is prescribed as a stimulating treatment for infertility for both women and men.

Indications

Chorionic gonadotropin is a hormone designed to maintain the corpus luteum during pregnancy. Due to this, this female gland of internal secretion is able to produce progesterone during the first 3 months of bearing a child. This hormone, in turn, contributes to the creation of a membrane of blood vessels in the uterus, due to which the developing fetus is successfully retained in it. In addition, chorionic gonadotropin repels maternal cells produced by the protective system, thereby protecting the unborn child.

The most common source of the hormone is female urine. Some manufacturers collect pregnant urine for subsequent extraction of chorionic gonadotropin. Subsequently, the substance is used to create drugs effective against infertility.

In addition, in women, the following diseases and conditions are indications for the use of the medication:

Hypofunction of the gonads associated with impaired pituitary and hypothalamus.
Dysmenorrhea. This term refers to pain in the abdomen, which is the result of cramping in the uterus during menstrual bleeding.
Ovarian dysfunction. This is a pathology characterized by a malfunction of this paired organ. In particular, inhibition of hormonal function occurs.
Anovulatory infertility. This is the inability to conceive a child due to the fact that in the female body the egg does not exit into the fallopian tube.
Corpus luteum insufficiency. This is a pathological condition in which progesterone is produced in an amount insufficient to attach a fertilized egg to the endometrium and ensure its normal development.

According to the instructions, "Chorionic gonadotropin" is prescribed for a successful pregnancy, and during lactation. Its introduction is advisable only in case of insufficiency of the luteal phase. In the presence of this pathological condition, the active substance enhances the production of progesterone, which, in turn, has a beneficial effect on the condition of the endometrium. If pregnancy and the period of breastfeeding are proceeding normally, the introduction of a solution containing hCG (chorionic gonadotropin) is impractical.

The hormone also performs an important function in the male body. It is designed to normalize testosterone synthesis in the testes. For men, chorionic gonadotropin is important during puberty and during hormone replacement therapy. The substance also controls spermatogenesis.

Indications for the introduction of the drug for men:

Hypogenitalism. This term refers to the insufficient development of the sex glands or a significant deterioration in their functioning.
Eunuchoidism. This is a disease in which there is a skeleton imbalance or a significant increase in body weight. The course of the disease is accompanied by inhibition of the functions of the sex glands.
Hypoplasia of testicles. This is an insufficient development of the male genital glands, as a result of which the size of the testicles is reduced.
Cryptorchidism. This is a congenital disease in which testicles do not descend into the scrotum.
Adiposogenital syndrome. This is a pathological condition of a neuroendocrine nature, with signs of underdevelopment of the gonads and obesity.
Pituitary dwarfism. Another name for the disease is dwarfism (delayed physical development and growth).
Sexual infantilism. This is a disorder in which the normal development of the reproductive system ceases, and the formation of sexuality is inhibited.
Oligoastenospermia. This is a decrease in the number of active germ cells.
Azoospermia. This is a disease in which there are no active germ cells in the ejaculate.

Thus, the drug "Chorionic gonadotropin" is prescribed for both women and men. The active substance stimulates ovulation and spermatogenesis, has a therapeutic effect in various diseases of the reproductive system, and is also responsible for the development of the organs of the reproductive system.

Structure

The active component of the drug is chorionic gonadotropin (1000 units, 1500 units, 500 units and 5000 units). As an auxiliary substance, mannitol is used. This is a six-atom alcohol from the sugar group.

The solvent is sodium chloride and water for injection. 1 ampoule contains 1 ml of liquid.

Release form

The drug is sold as a lyophilisate (dry powder), packaged in 5 ml vials. Each of them contains 500, 1000, 1500 or 5000 PIECES of chorionic gonadotropin.

The solvent for the powder is poured into 1 ml ampoules. Then the product is placed in the secondary packaging - cardboard boxes. In each of them there are 5 bottles with dry powder and 5 ampoules with solvent.

Contraindications

The drug "Chorionic gonadotropin" (1000 units, 500 units, 1500 units or 5000 units) is not prescribed for men and women in the presence of the following diseases and conditions:

Hypersensitivity to one or more components of the drug.
Pituitary neoplasms (both malignant and benign).
Ovarian cancer.
Neoplasms on the gonads of a hormonal-active nature.
The early onset of menopause.
Lack of gonads (this can be either congenital or acquired pathology).
Thrombophlebitis.
Hyperprolactinemia.
Adrenal insufficiency.
Hypothyroidism

“Chorionic gonadotropin” (1000, 500, 1500, 5000 IU) is prescribed with caution to people of adolescence, as well as people suffering from frequent episodes of migraine, hypertension, bronchial asthma, coronary heart disease and chronic renal failure.

In the process of an individual conversation with the attending physician, the list of contraindications can be expanded.

Dosage and administration

According to the instructions "Chorionic gonadotropin" (1000, 1500, 500, 5000 UNITS) is intended for intramuscular administration. Injections are recommended to be carried out in a medical institution, but it is allowed to carry them out independently at home or in any other conditions comfortable for the patient.

Algorithm of intramuscular administration of “Chorionic gonadotropin” (1000, 500, 1500, 5000 PIECES):

Initially, it is necessary to prepare all the materials and tools that will be needed. These include: a solution of the drug (lyophilisate mixed with liquid from an ampoule), a disposable sterile syringe, medical alcohol or special wipes soaked with it (they can be replaced with ordinary cotton wool). Before handling, wash your hands thoroughly with soap and water.
Then you need to choose the injection site. This may be the anterior thigh muscle or gluteus. The latter is the most developed. In addition, with the introduction of the drug into the anterior muscle of the thigh, the risk of various complications is higher (due to the incorrect injection). In this regard, it is recommended to choose a gluteal.
It is necessary to calculate the injection site. For this, the gluteus muscle visually needs to be divided into 4 parts. The outer upper zone is the outer quadrant. The desired point is exactly in the middle of it. The introduction of the drug into this area is a guarantee that the needle will not touch the blood vessels, nerves or bone tissue.
Open the syringe, fill it with the necessary amount of medicine. Then it is important to release the air that has accumulated from the medical device. Set aside the syringe on a clean tray, having previously closed it with a cap.
Position yourself in front of the mirror in such a way as to see your own buttock and the intended injection site. Bare this area. Transfer the weight to the other leg so that the necessary part of the body is relaxed as much as possible.
Wipe the injection site with a medical napkin or a piece of cotton wool soaked in alcohol. Take the syringe vertically in your hand, remove the cap and bring it to the buttock.
With a quick movement, make an injection into the muscle so that the length of the open area of the needle was about 1 cm above the skin. Slowly press the piston until the medicine is finished in the syringe.
Pull out the needle sharply and apply cotton wool or an alcohol wipe to the injection site. Keep until the blood stops. The injection site is also recommended to massage. This will help to avoid condensation and will contribute to a good resorption of the medicine.

The duration of the course and dosage of "Chorionic gonadotropin" (1500 PIECES, 500 PIECES, 1000 PIECES, 5000 PIECES) are determined individually by the attending physician. Unless otherwise specified by a specialist, standard guidelines should be followed:

For men, a drug is administered twice or thrice a week. The course of treatment is 28 days. Then you need to take a break for 4 weeks. After this, the course must be repeated. There are 3 or 6 of them for 6 months or 1 year. If you enter "Chorionic gonadotropin" (1500, 500, 1000 or 5000 units) without interruption and for a long time, the risk of antibody formation and pituitary dysfunction will significantly increase.
The method of application for anovulation, the course of which is accompanied by normal follicular maturation, is as follows. The course of treatment should be started from the 10th or 12th day of the menstrual cycle twice or thrice a day at a dosage of 3000 units. Then you need to take a break for 2 or 3 days. It is also allowed to administer the drug in a dosage of 1,500 units 6 or 7 times every other day.
The use of pituitary dwarfism and sexual infantilism is as follows. "Chorionic gonadotropin" (5000, 1500, 1000, 500) is administered 1 or 2 times a week in a dosage of up to 1000 units. The duration of the course is 1-2 months. If necessary, it can be repeated.
To induce ovulation, the drug is administered once at a dosage of 5000-10,000 units. A similar pattern must be followed when conducting additional reproductive activities.
In pituitary insufficiency, it is advisable to start a course of treatment only after preliminary follicle-stimulating therapy.

Often, the drug is prescribed for men with a diagnostic purpose. In this case, the drug must be administered 5 days in a dosage of 1500 or 3000 units.

In children, treatment with "Chorionic gonadotropin" is most effective until they reach the age of 10 years. The dosage regimen and duration of the course of therapy are determined by the pediatrician based on the existing disease, its severity, as well as the individual characteristics of the child’s health. In the absence of specialist recommendations, it is necessary to follow a standard treatment regimen. According to the instructions for children, a medication must be administered twice a week for 1-1.5 months at a dosage of 1000 or 1500 units.

Side effects

According to reviews, "Chorionic gonadotropin" is well tolerated by most patients. Nevertheless, the risk of adverse reactions remains.

These include:

Headache.
Painful sensations, hyperemia at the injection site.
Skin reactions.
The rapid onset of feelings of fatigue.
Psycho-emotional instability.
Inexplicable feeling of anxiety.
Depression.
Impaired pituitary gland functioning.

In addition, in men, the following side effects may additionally occur:

Swelling of the extremities.
Urinary retention.
High nipple sensitivity.
An increase in the size of the testicles.

Against the background of prolonged use, degenerative changes in the gonads can occur. There is also a risk of developing atrophy of the ejaculatory tubules and a decrease in the number of spermatozoa in the ejaculate.

Overdose

This condition can occur when taking the drug in an amount significantly exceeding the maximum allowable rate.

The following symptoms are alarming:

pain in the abdomen;
a feeling of tension in the same zone;
vomiting
labored breathing;
diarrhea.

In women with an overdose of Chorionic Gonadotropin, cysts form on the ovaries, which can burst at any time. In addition, fluid may begin to accumulate in the abdominal and pleural cavities.

The antidote of the drug is unknown. Overdose treatment involves symptomatic therapy.

Analogs

Currently, the pharmaceutical market is selling several types of drugs, the active component of which is human chorionic gonadotropin.

The most common analogues of a medication:

"Rotten." It is also a lyophilisate for the preparation of a solution. The list of indications is identical to "Chorionic gonadotropin", but the side effects of the drug are significantly greater.
"Profazi." Available in two dosages - 2000 and 5000 units. The tool has the same indications, while the list of restrictions is wider.
The Horagon. Lyophilisate is sold complete with a solvent in a dosage of 1,500 and 5,000 units. Among all analogues, it has the most impressive list of contraindications.
"Choral." Instructions for use are identical to "Chorionic gonadotropin."
"Ecostimulin." Available in the form of a lyophilisate for the preparation of a solution intended for both intramuscular and subcutaneous administration.

If for any reason the patient wishes to purchase an analogue of the drug, it is necessary to obtain the permission of the attending physician. This is due to the fact that each medication has certain contraindications, a different dosage and treatment regimen.

Reviews

According to patients, “Chorionic gonadotropin” is well tolerated by most people. Moreover, the tool has a high degree of effectiveness.

Doctors most often prescribe Chorionic Gonadotropin to their patients due to the fact that the drug helps to cope with the existing pathology or significantly improve its course in a short time. In addition, you can purchase it at almost any pharmacy.

Finally

Chorionic gonadotropin is a hormone that can be found in the female placenta. At the same time, manufacturers most often excrete a substance from the urine of pregnant women.

The drug "Chorionic gonadotropin" is intended for the treatment of disorders of the reproductive system in both women and men. The drug is administered intramuscularly at the dosage indicated by the doctor. In the absence of specialist recommendations, it is necessary to follow a standard treatment regimen.

"Chorionic gonadotropin": instructions for use, analogues and reviews