The drug "Kombilipen", the indications for the use of which will be given below, is a multivitamin complex. The product contains thiamine hydrochloride (vitamin B1). This element helps provide cells with glucose. With its deficiency, deformation of the cells and an increase in their size occur. This, in turn, causes their dysfunction. Pyridoxine hydrochloride (B6) is directly involved in metabolic processes in the central nervous system. This component provides normal impulse transmission, is responsible for braking and excitation. B6 is also involved in the synthesis of adrenaline, norepinephrine, and transport of the nerve membrane element - sphingosine. Cyanocobalamin (B12) promotes hematopoiesis. The component provides the formation of choline, the main substrate for the synthesis of acetylcholine, and also participates in the synthesis of nucleic and folic acids, myelin. Cyanocobalamin enhances the regenerative properties of tissues.
Means "Combilipen". Indications for use
The drug is recommended for trigeminal neuralgia, polyneuropathy of various nature (including diabetic and alcoholic). In case of pain against the background of pathologies of the spine, the medicine "Combilipen" is also prescribed. Indications for use in these cases are as follows: lumbar ischialgia, cervical, radicular, cervicobrachial, lumbar syndromes, intercostal neuralgia. An agent is also prescribed for inflammation of the facial nerve.
Dosage regimen
The drug "Kombilipen" (tablets), the instruction recommends drinking after meals. Dosage for adults - 1 pc. from 1 to 3 times / day. Duration of admission is determined by the doctor. At higher dosages, the duration of therapy should not exceed 4 weeks. The medicine "Kombilipen" (injections) is prescribed intramuscularly. The recommended dosage is 2 ml daily. Injections are carried out within 5-7 days, after which - 2 ml no more than 3 times a week. The duration of therapy is determined by the doctor.
Side effects and contraindications
The tool is not prescribed for individual intolerance of its components, during the prenatal period, to nursing patients. Therapy is not recommended for patients with cardiovascular failure. The drug "Combilipen", the indications for use of which are listed above, can provoke allergic reactions. Usually, they appear against the background of individual hypersensitivity. In patients in such cases, angioedema, skin itching, urticaria are observed. Hyperhidrosis, tachycardia, acne are also negative consequences.
additional information
The combined use of the Combilipen preparation with the Levodopa medication is not recommended due to the likelihood of a decrease in the therapeutic activity of vitamin B6. Cyanocobalamin is incompatible with heavy metals and their compounds. The simultaneous use of the drug "Combilipen" with sodium phenobarbital, riboflavin, metabisulfite, dextrose is not recommended. Incompatibility of B1 with compounds that have redox properties (acetate, iodide, mercury chloride and others) is noted.