"Alimta" (pemetrexed) is an antitumor drug in the form of a lyophilizate (powder, dried in a special way). It is used to prepare a solution for intravenous infusion.
Entering the blood after drip, pemetrexed is distributed in cells, where it quickly turns into a polyglutamate form, which lingers in tumor tissues, disrupting metabolic processes in them and interfering with their growth.
We will tell more about how the aforementioned drug is used and where it is more profitable to buy the Alimta drug, later in the article.
What is a generic drug, or where to buy Alimta medicine cheaper
Many patients have to ponder where Alimta can be bought cheaper. It is widely known that anticancer drugs are expensive, and what is described in this article is no exception. So, in Moscow, for example, for the Alimta lyophilizate, the price ranges from 43,000 to 74,000 rubles.
To avoid excessive spending, patients acquire generics. These are funds issued under license, with strict adherence to technology, and having the same active substance as the branded drug. Their cheapness is explained not at all by the lack of proper effect, but by the fact that the price does not include the costs of developing and promoting such drugs on the market.
So, on the site can be purchased from India by Natco Pharma Ltd. generic of the described drug - Pemnat . Its cost here will be from 18,000 rubles. per bottle, which, of course, is much cheaper and more affordable for people struggling with a serious illness.
Indications for use
Treatment with Alimta should be carried out only under the supervision of a specialist who has experience working with cancer patients. Pemetrexed is prescribed for the diagnosis of malignant neoplasms in the lungs and bronchi, as well as for the detection of pleural mesothelioma.
Contraindications and side effects
Alimta lyophilisate, the instructions for which are provided in this article, are contraindicated for pregnant and lactating women, children (since its use in this category of patients has not been investigated), as well as those who have an increased sensitivity to the components of the drug.
During treatment, patients may experience the following side effects:
- hematopoietic system disorders - leukopenia, anemia, neutropenia;
- nausea, vomiting;
- the development of anorexia;
- the appearance of a rash and peeling on the skin;
- high fatigue;
- diarrhea;
- development of pharyngitis.
Dosage and administration
"Alimta" is administered as an intravenous infusion over 10 minutes.
When treating malignant neoplasms of the lungs and non-small cell carcinoma of the pleura, it is recommended during the first line of therapy, in combination with Cisplatin, to administer 500 mg / m² every first day of the 21-day cycle. In this case, the dose of “Cisplatin” should be 75 mg / m² and administered as an infusion approximately half an hour after pemetrexed.
With monotherapy, only 500 mg / m² of the described drug is administered every first day of the 21-day cycle.
How to prepare a solution
As a solvent for the drug "Alimta" is used NaCl (0.9% solution). To obtain the finished drug, the lyophilisate (100 mg) is diluted with sodium chloride to a concentration of 25 mg / ml. After this, the bottle is shaken, and the result should be a clear, colorless solution. Permissible variation in its color to a yellowish or yellow-green color.
The resulting pemetrexed solution must be further diluted with sodium chloride solution to obtain a volume of 100 ml. And before the introduction, you should examine it for the presence of undissolved particles and color changes.
According to the instructions attached to the Alimta preparation, use of the product should be done no later than 24 hours after preparation.