In the article, we consider the most effective medications for gonorrhea.
Gonorrhea is considered one of the most common diseases that is transmitted through sexual contact. Men and women face this problem equally, but because of the structural features of the reproductive and reproductive systems, the disease in different sexes proceeds with some features. In this case, the treatment is absolutely similar.
Gonorrhea, or gonorrhea, is a common disease that is triggered by a pathogen called gonococcus. This bacterium is highly sensitive to environmental influences, therefore, quickly dies outside the host organism. Thus, it is almost impossible to become infected with gonorrhea in a domestic way. Basically, the disease is sexually transmitted. The treatment of gonorrhea is selected taking into account that the pathogen is not resistant to the selected medications for gonorrhea.
Description, symptoms of this pathology
The most pronounced signs of gonorrhea in males. Typically, the main symptoms of gonorrhea are the following:
- Discharge from the urethra of purulent contents.
- Soreness and burning during urination.
For women, in most cases, the pathological process occurs in a latent form. Only in the most advanced cases are discharges with an unpleasant odor observed, as well as bleeding outside the menstrual cycle, painful urination and pain in the abdomen. A concomitant disease of gonorrhea is rectal gonococcus disease.
Complications of this sexually transmitted disease
Most often, complications occur in men against the background of gonorrhea in the form of epididymitis and an inflammatory process in the testicles. Often, such complications cause infertility.
Medications for gonorrhea in men should be selected very carefully.
In women, often due to gonorrhea, inflammation of the uterus and appendages develops, which in turn can also provoke a lack of the possibility of conception.
In addition to the area of the human reproductive system, gonococci can spread to other systems and organs. Microorganisms enter the bloodstream and spread throughout the heart, liver, joints, and even the brain.
Pathology diagnostics
If we are talking about the acute stage of gonococcal lesions of the body, when pronounced urethritis is detected, a smear collection is enough to diagnose gonorrhea for research in the laboratory. With a chronic course of pathology, the clinical picture is not as pronounced as in the case of the acute form. In this case, bacteriological culture for the presence of a nutrient medium will be required. In addition, the PCR method is used. Clinical studies to detect gonorrhea in women do not differ from the male version. Tripper is excluded if gonococci are not found in repeated smears.
What medications for gonorrhea exist?
Gonorrhea treatment: basic principles
Gonorrhea is a pathological process provoked by harmful microflora. Thus, the main principle of treatment of this disease is the administration or injection of antibacterial drugs.
Before prescribing treatment to a patient, a specialist evaluates the results of smear laboratory tests. If, in addition to gonococci, other infectious pathogens have not been identified, there is no need to prescribe combination drugs. In some cases, other sexually transmitted diseases are also added to the gonococcal lesion, which requires a combination of several antibiotics.
Before prescribing treatment, a test is carried out for the sensitivity of gonococci to certain antibacterial substances. This is due to the fact that the body of a pathogenic bacterium is able to develop resistance to certain drugs. Previously, the treatment of gonorrhea was not particularly difficult, since even ordinary penicillin was able to get rid of pathogenic microflora. Today, such treatment will not give a result and more modern drugs based on old components are required. In addition, it is necessary to carefully approach the issue of choosing a particular drug.
A doctor will help you find the best cure for gonorrhea in men and women. At the first symptoms, you should contact a medical institution and undergo an examination.
Penicillin drugs are used quite widely, but they have little in common with the old generation of drugs. The active components of modern drugs are thoroughly cleaned, in addition, their numerous derivatives are used, which makes them effective in combating gonococci. New drugs have a prolonged effect, they retain a high concentration in the composition of urine and blood over a long period of time. It is this property that allows them to most effectively affect pathogens.
The main groups of antibacterial drugs that are able to fight against gonococci are the following:
- Penicillins.
- Tetracyclines.
- Macrolides.
- Cephalosporins.
- Azalids.
The choice of medication for gonorrhea should be made by the attending physician, since all antibiotics have contraindications and possible adverse reactions.
Penicillins
The group is represented by various drugs, however, the most common among them are the following:
- Ampicillin is an effective medicine for gonorrhea. This is the most famous and often prescribed drug from the category of penicillins. At the moment, its absolute effectiveness is being questioned by doctors. However, with an uncomplicated form of tripper, the drug manifests itself most effectively. If you follow the prescribed treatment regimen, you can achieve the optimal concentration of the drug in the blood. After repeated laboratory studies, a decision is made to prolong the treatment.
- Ampioks. It is a combined preparation, the composition of which immediately includes two active substances: oxacillin and ampicillin. The treatment regimen is selected individually and can reach from one to two weeks. The duration of treatment depends on the form of the course of gonorrhea.
- Amoxicillin. This drug is the newest and has a wide range of effects on harmful microorganisms. Doctors are gradually switching to this particular treatment option, prescribing a ten-day course of the drug to patients.
The duration of therapy may vary depending on the severity of the symptoms of gonorrhea. Dosage is also selected based on the patient's condition and the nature of the course of the disease.
In the treatment of gonorrhea, it is the penicillin drugs that have proven themselves well. As a rule, the choice of other groups of antibiotics may be required if the patient has an allergic reaction to penicillins or gonococci demonstrate resistance to the selected treatment. Attention is also drawn to the severity of adverse reactions.
What other medicines are prescribed for gonorrhea?
Tetracyclines
Tetracycline antibiotics are often used to treat gonorrhea urethritis in men. In this case, the stage of development of the pathological process does not matter, chronic and acute gonorrhea are treated by taking similar dosages. The main drugs from this group are:
- "Tetracycline." As the name implies, this is a single drug based on the active ingredient of the same name. Treatment is carried out within 2-3 weeks.
- Doxycycline. Also included in the group of drugs based on tetracycline. The therapeutic course cannot exceed 10 days.
- "Metacycline." When it comes to treating the uncomplicated type of gonorrhea, the drug is prescribed for no more than one week.
Preparations from the category of tetracyclines have a minimal set of adverse reactions and contraindications, which allows them to be widely used in medical practice, including for the treatment of gonorrhea. However, in the latter case, microorganisms quickly develop resistance to tetracyclines, which may require replacement of the medication for gonorrhea in women and men in the middle of therapy.
Macrolides
This is a new generation of antibacterial drugs that have a wide spectrum of action. The drugs are well tolerated subject to therapeutic dosages, while they have a small number of adverse reactions and contraindications, which distinguishes them among similar groups of antibiotics. In this group, the following medications are allocated in tablets for gonorrhea in men and women:
- "Erythromycin." It is necessary to take the drug strictly following the scheme prescribed by the doctor. Treatment is carried out for at least seven days.
- Wilprafen. A good cure for chronic gonorrhea. Gonococci have not yet been able to develop resistance to this drug of a new generation. "Vilprafen" is taken three times a day, with a course of at least 10 days.
- "Roxithromycin." The drug is semi-synthetic and is recommended for use in the treatment of gonorrhea in an inpatient setting. The drug is taken once. This is sufficient for the penetration of the active component into gonococcal cells and their death.
Many do not consider macrolides to be full-fledged antibiotics. However, their reception requires consultation with a doctor.
Cephalosporins
Not always oral therapy gives a positive result. If there is no dynamics in the patient’s condition, the administration of some drugs is allowed. Ceftriaxone is considered especially effective in the fight against gonococcus. It goes well with other drugs, but monotherapy is also allowed. Drug treatment is one week. Injections are given in the morning and in the evening with an interval of 12 hours.
"Sifloks" is prescribed for the treatment of acute forms of gonococcal lesions. It is taken in combination with antihistamines, which helps prevent the development of an allergic reaction.
You can choose the best cure for gonorrhea among azalides.
Azalides
Azalides, also called bacteriostatic antibiotics, widely affect harmful microorganisms. In the treatment of gonorrhea, the following drugs are most common:
- "Sumamed."
- Asinom.
- "Azithromycin."
Azalides have the property of being rapidly absorbed into the bloodstream. The active components of the above components penetrate the gonococcal cells and make a change in their protein synthesis, which ultimately leads to cell death.
Drugs from this group are considered highly effective agents that actively fight cocci, as well as pale spirochetes and gram-negative pathogens. When prescribing these medications for gonorrhea in men and women, the doctor takes into account their poor compatibility with the penicillin series and cephalosporins. Azalides are able to actively penetrate into tissues, which leads to their frequent use in the treatment of venereal pathologies.
Therapy for mixed infection
Quite often, the appearance of gonorrhea is accompanied by additional pathology. Treatment of several types of pathogenic microflora at once requires an integrated approach. Sometimes antibacterial drugs have a wide spectrum of action, which allows you to stay on monotherapy. However, it should be borne in mind that in this case prolonged treatment may be required, as well as the adjustment of standard dosages of gonorrhea medicines in tablets. Consider several combinations of drugs in the treatment of various diseases:
- Gonorrhea in combination with chlamydia. In this case, drugs based on tetracycline and penicillins will be required. As a rule, in this case, Ceftriaxone is prescribed in combination with Doxycycline. The dosage is selected taking into account the severity of the disease and the patient's well-being.
- Gonorrhea in combination with trichomoniasis. The basis of the therapeutic regimen is any variant of antibacterial drugs that have a detrimental effect on gonococci. As an auxiliary drug, Metronidazole is indicated, which is active against Trichomonas.
- Gonorrhea combined with syphilis. The latter is detected in laboratory studies. It is especially important to take preventive measures in case of doubtful sexual intercourse. With this combination, Bicillin is at the heart of the treatment. The standard scheme involves the administration of the drug every five days. The total number of injections should be at least 10.
Supplementation of topical medication should be discussed with your doctor. The specialist evaluates the condition of the patient and decides on the necessary additions to the treatment regimen. Various creams and suppositories are used as adjuvants.
We looked at which medicines treat gonorrhea.