The medicine "Deprenorm MV" is a drug with a modified release. The active ingredient is trimetazidine dihydrochloride. The drug "Deprenorm" instructions for use are classified as antianginal drugs that improve myocardial metabolism. The medication has an antihypoxic property.
The drug directly enhances the activity and metabolism of cardiomyocytes and neurons in the brain. Due to the rationalization of oxygen consumption, increasing energy potential, activation of oxidative decarboxylation, a cytoprotective effect is carried out. Describing the medicine "Deprenorm", the instruction indicates its properties to maintain normal contractility in the myocardium, to prevent intracellular depletion of creatine phosphate and ATP. Under the influence of a medication in conditions of acidosis, the state of membrane ion channels is normalized, the level of potassium ions inside the cell is normalized. The medicine prevents the accumulation of sodium and calcium in cardiomyocytes. The drug "Deprenorm" (instructions for use contains such data) reduces the level of phosphates, reduces acidosis within cells, prevents the damaging activity of free radicals, and ensures the integrity of cell membranes. In addition, the medication helps to increase the duration of the electric potential.
According to experts, when using the medicine for angina pectoris, the frequency of seizures decreases and the need for taking nitrates decreases. Two weeks after the start of therapy, tolerance to physical activity increases, pressure drops (arterial) decrease. The medicine "Deprenorm" (reviews of many patients indicate this) helps to improve hearing, reduce tinnitus. In addition, dizziness is reduced. Against the background of vascular eye pathologies, an improvement in the functional state of the retina is noted.
The medicine "Deprenorm" recommends the use of the drug for chorioretinal vascular disorders, cochleo-vestibular disorders of ischemic origin (hearing impairment, tinnitus). The drug is indicated for dizziness of a vascular nature, as well as to prevent angina attacks (in combination with other drugs).
Medication "Deprenorm" instructions for use does not allow for appointment with renal failure, severe disorders of the liver, pregnancy. Contraindications include individual intolerance, children's age (up to eighteen years), breastfeeding.
The drug is taken orally. Dosage - seventy milligrams (two tablets), divided into two doses. The duration of treatment is set individually for each patient. Tablets are recommended to be taken with food.
The medicine "Deprenorm" can cause vomiting, nausea, gastralgia and other disorders of the gastrointestinal tract. In some cases, itching of the skin, a feeling of palpitations, and headache may occur. As practice shows, and numerous patient reviews indicate that these adverse reactions are rare.
The drug is not intended to eliminate angina attacks. If seizures occur or intensify, consult a doctor. Probably, in this case, an adjustment of the treatment regimen will be required.
The studies did not reveal the effect of the drug on the ability to work with equipment, machinery or driving vehicles.
The shelf life of Deprenorm is two years. Do not take the medicine after the specified time.
Before taking the medicine, "Deprenorm" should consult with your doctor.