The drug "Vestikap" includes beta-histine dihydrochloride as an active substance. Additional components: lactose monohydrate, potato starch, sodium carboxymethyl starch, magnesium stearate, colloidal
silicon dioxide. Vesticap tablets are not available. The medicine is made in the form of capsules of 8 and 16 milligrams, they differ in body color. Inside the capsules there is a powder of a white or slightly cream shade. In pharmacies, the medicine can be purchased for 140 rubles (and higher, depending on the point of sale). Here is such a low price for Vestikap.
Instruction The mechanism of action of the drug
The tool belongs to the category of histamine preparations. The active substance affects the H3 and H1 receptors in the vestibular nuclei of the central nervous system and in the inner ear. Due to direct agonistic action, permeability and microcirculation in capillaries improves, endolymph pressure stabilizes in the cochlea and maze. In this case, an increase in blood flow in the basilar artery is noted. The medicine accelerates the restoration of function after vestibular unilateral neurectomy. This effect is manifested due to antagonism with H3-histamine receptors. As a result, vestibular central compensation is facilitated and accelerated. The Vestikap medication (the instructions for use contain such information) has a pronounced central effect, dose-dependently reduces the generation of potentials in the neurons of the medial and lateral vestibular nuclei. A stable therapeutic effect is observed after two weeks.
Pharmacokinetic properties
The product undergoes rapid absorption. There is a low association with plasma proteins. Within three hours, the concentration of the drug in the blood reaches a maximum. In the process of decomposition, 2-pyridylacetic acid and demethylbetagistin are formed. Almost completely (80-90%) is excreted with the kidneys throughout the day. A small part of the decay products is excreted through the intestines.
Appointment
The medicine “Vestikap” recommends the use instructions for Meniere's syndrome, accompanied by tinnitus, hearing loss and dizziness. The medication effectively eliminates manifestations that complicate the condition, such as nausea and vomiting. The medication is prescribed for symptomatic therapy of vertigo (dizziness of a vestibular nature).
Contraindications
The drug is not recommended for glucose intolerance, hypersensitivity to the components of the drug during lactation. Treatment for pregnant and lactating women is contraindicated. Do not prescribe medication "Vestikap" (instructions for use warns about this) in childhood. Nursing patients should stop feeding for the entire period of therapy. Caution during admission should be observed in the presence of ulcerative lesions of the digestive system (including a history of), bronchial asthma, pheochromocytoma. Patients with the mentioned pathologies should undergo treatment under close medical supervision. In some cases, you may need to adjust the reception schedule.
Dosage regimen
Medication "Vestikap" instruction for use recommends drinking with food. For capsules of 8 milligrams, a single dosage is 1-2 pcs., In 16 mg - 1 pc. The drug is taken three times a day. As a rule, improvement occurs already at the initial stages of therapy. However, a stable effect is observed after fourteen days. Over several months, the activity of the medication may increase. Therapy is long. The duration of the course is set individually by the specialist.
Side effects
The medicine provokes abdominal pain, vomiting, angioedema (rarely). Undesirable effects include dyspeptic symptoms, bloating, rash. In the event of the occurrence of these adverse reactions, consult a specialist. In case of an overdose, the drug in question provokes an exacerbation of these symptoms. Intoxication is accompanied by drowsiness (in the case of taking up to 640 mg of the drug), cardiovascular complications (when taking more than 640 mg or when combined with other medicines). In such situations, symptomatic treatment is prescribed, and it is necessary to visit a doctor. With timely contact with a specialist, the risk of complications is significantly reduced, and manifestations of intoxication are eliminated in a short time. As first aid measures, gastric lavage is recommended.
How to replace the medication? The most popular analogues
Vestikap, as a histamine preparation, has a lot of synonyms (or generics) that have a similar therapeutic effect. The best option would be the treatment with the original Betaserk remedy. However, in comparison with others, this medicine is quite expensive (about 400-600 rubles). The most popular and inexpensive drugs in Russia, which can be replaced by Vestikap, include Tagista and Vestibo. All of them contain one active substance, however, in different concentrations. Depending on its content, the price is also set.
The drug "Vestibo"
Available in tablet form. The drug has a slight agonistic effect on H1 receptors. The medication exhibits vasodilating and histamine-like activity. A rather powerful effect on the H3 receptors is noted. The drug does not provoke drowsiness and does not have a sedative effect, like some other analogues of Vestikap. Means "Vestibo" is not recommended in the first trimester, with caution (for health reasons) is prescribed in the second and third trimesters of pregnancy.
The medicine "Tagista"
The medication can be prescribed both as a treatment and with the goal of preventing vestibular dizziness of various etiologies. The drug is also available in tablet form. Contraindications include age up to 18 years, pregnancy. Do not prescribe medication to nursing patients. When taking the drug, a disturbance in the gastrointestinal tract, a hypersensitivity reaction, and Quincke's edema can be noted .
What are the reviews about Vestikap?
In general, with regard to the tolerability of the drug, the words of the patients indicate that the drug rarely provokes side effects. The undesirable consequences that arise, as a rule, are eliminated after the medication is canceled and do not require additional intervention. Moreover, experts say that
the drug does not affect the speed of psychomotor reactions and the ability to concentrate. In this regard, the medication is allowed for admission to persons whose activities are considered potentially dangerous. Doctors respond positively to the effectiveness of the drug. However, in some cases, the therapeutic effect increases over several months.
additional information
The drug "Vestikap" is suitable for use for three years. Keep the medicine in a dark place, away from children. The temperature should be no more than 25 degrees. Experts note that the medicine "Vestikap", like similar medicines of this group, is considered a fairly strong drug, despite the fact that in some cases the action develops gradually. The product is produced by the Russian pharmaceutical company Ozone. The cost of the drug varies in the range from 150 to 200 rubles (or more). The product is dispensed with a prescription.