In the article, we consider the instructions for use, price and reviews for the Ovestin medication.
The main active ingredient in tablets is estriol. In addition, auxiliary components were used: silicon dioxide, stearate, magnesium povidone, lactose monohydrate, potato starch, amylopectin.
The main component of the Ovestin candles is estriol. As additional components, Vitepsol S 58 is used.
Additional components in the manufacture of the preparation in the form of a cream are: water, sodium hydroxide, lactic acid, chlorhexidine hydrochloride, sorbitan stearate, stearyl alcohol, polysorbate, glycerin, cetyl alcohol, octyldodecanol, cetyl palmitate. Reviews about "Ovestin" are abundant.
Pharmacological forms
The medicine is produced by the manufacturer in the form of tablets, cream, candles. Ovestin tablets are round, have a beveled edge. On one side of the tablet there is a label “DG” and the number “8”, as well as a dividing risk. On the other side is the marking "ORGANON".
"Ovestin" in the form of a vaginal cream has a uniform mass, its color is whitish or pure white. It has a specific smell. Ovestin Cream Reviews
Suppositories "Ovestin", intended for vaginal administration, have a white or cream color. The shape is torpedo-shaped, the longitudinal section and the surface are homogeneous.
Pharmacological effects
The main component of the medication is estriol, which is a female hormone. It is a short-acting hormone. Able to stimulate proliferative processes in the endometrium. The drug helps to accelerate the process of regeneration of the epithelium of the mucous membranes of the vagina, optimize acidity, restore the natural microflora in the vagina. As a result, local immunity increases, a protective barrier appears that prevents the development of pathogenic flora.
Feedback on the use of "Ovestin" is mostly positive.
Indications for use
The drug is prescribed to women if there are the following indications:
- Atrophic colpitis.
- Prevention of complications in the background of operations performed through the vagina.
- Prevention of inflammation of the urogenital region.
- Diagnosis of diseases with an unclear result of a cytological smear.
- Infertility due to cervical factor.
- Urinary incontinence.
- Soreness when urinating, frequent urination.
- Changes in the vaginal mucosa, having an atrophic nature and due to age against a background of estrogen deficiency.
Contraindications
"Ovestin" in any pharmacological form is contraindicated for use:
- In acute liver diseases, or if changes in liver tests are noted.
- With porphyria.
- If there is a history of arterial or venous thromboembolism.
- With bleeding from the vagina, which has an unclear etymology.
- With an estrogen-dependent malignant tumor.
- With oncological pathologies of the mammary glands, with suspected breast cancer, with a history of breast cancer.
- During pregnancy.
- With intolerance to any of the components that make up the drug.
Side effects
According to reviews of Ovestin, local itching or irritation may develop amid its use. The occurrence of tension or soreness of the mammary glands is not excluded. As a rule, such negative effects are observed only at the initial stage of the use of the drug in the form of suppositories. However, in some cases, this may indicate an excess of the required dose of Ovestin.
The occurrence of breakthrough bleeding, metrorrhagia, and blood discharge, characterized by acyclicity, is not excluded.
This is confirmed by the tool "Ovestin" instructions for use and reviews.
Annotation to the drug contains information that some other side effects may occur. Similar phenomena are noted with estrogen-progestogen therapy. However, there is not enough information to claim that Ovestin is different in this.
We are talking about the development of estrogen-dependent tumors of a malignant or benign nature, the occurrence of thrombosis, heart attacks, myocardial infarction, gall bladder diseases, dementia, inflammation of the skin and subcutaneous layer.
Instruction for use
When prescribing the drug, the patient should strictly follow the doctor's recommendations and instructions for use.
The effectiveness of the drug does not depend on the pharmacological form used. Regardless of the form of the drug, it should be used once a day.
If "Ovestin" in the form of a vaginal cream is prescribed, then it should be administered into the vagina before bedtime. For administration, a special applicator is used. In the initial stages, the cream should be used every day. With the onset of improvement, the frequency of its use can be reduced, the introduction in this case can be carried out twice a week. The duration of the course of therapy depends on the characteristics of the disease.
"Ovestin" in tablets is indicated for administration in a dosage of 2-4 pieces once a day. Duration of admission is one month. Subsequently, the dosage should be reduced to 1-2 tablets once a day. Higher doses are acceptable if the patient has incontinence.
"Ovestin" in the form of vaginal suppositories should be introduced into the vagina once a day. With a decrease in the severity of symptoms, the frequency of use is reduced. The introduction is carried out twice a week.
In preparation for surgery, which will be performed through the vagina, Ovestin in the form of suppositories is prescribed 14 days before the operation. The introduction should be carried out once a day. A similar pattern of use should be followed when prescribing a medication in the form of a cream. According to reviews, Ovestin cream is most often well tolerated.
If you skip the next use of Ovestin, you should take the following dose according to this scheme: if the interval between doses is less than 36 hours, then it is recommended to take the missed dose and continue the usual treatment; if the interval is more than 36 hours, then the usual treatment should be continued.
Reviews of "Ovestin" and side effects are discussed below.
In case of an overdose of the indicated drug, nausea, vaginal bleeding, and vomiting may occur. Overdose therapy is symptomatic.
Interaction with other medicines
Adverse interactions of "Ovestin" with other medicines were not noted.
However, it is important to consider that, due to its pharmacological properties, Ovestin can interact with St. John's wort preparations, antibiotic agents, antiretroviral and anticonvulsant drugs.
There is evidence that while taking estriol, the therapeutic effect of theophylline and some corticosteroids increases.
Special instructions for use
Therapy with high doses of Ovestin for longer than two weeks is prohibited.
If long-term therapy is necessary, regular visits to the gynecologist, examination of the mammary glands, and control of the coagulogram are indicated.
In the treatment of postmenopausal symptoms, hormone replacement treatment can only be used if the symptoms are pronounced and significantly affect the patient's quality of life.
Before starting treatment, a woman needs to familiarize herself with information about changes in the mammary glands that can occur during the use of estriol, and the occurrence of which is important to inform the doctor.
If during the treatment with "Ovestin" there are factors related to contraindications, the use of the drug must be stopped.
Estrogens provoke fluid retention in the body, so it is important for patients with heart failure and kidney disease to monitor their health.
Analogs
The main analogues of Ovestin in the current component are: Tefestrol, Mikrofollin-forte, Gormopleks, Dimestrol, Kolpotrofin, Klimara, Klimen. All of these drugs contain estriol, some of them are much cheaper than Ovestin. However, the patient, first of all, should be interested in the effectiveness of the drug, and not its cost. Therefore, the feasibility of replacing the drug should be discussed with a specialist.
"Ovestin" in the treatment of children
When treating children, Ovestin can only be prescribed by a doctor. Sometimes a drug is used to treat synechia in children. In the presence of such a diagnosis, the cream should be used exclusively in those dosages and according to the scheme that was indicated by the doctor.
Cost of Ovestin
The average cost of Ovestin in the form of tablets is at the level of 900 rubles for 30 pieces. "Ovestin" in the form of candles will cost about 1100 rubles. "Ovestin" in the form of a cream costs an average of 1300 rubles per tube of 15 g.
Reviews about Ovestin
About the drug in the form of candles, women leave mostly positive. Separately, the effectiveness of the drug with menopause is noted. The effectiveness of Ovestin cream and tablets is often noted in reducing the symptoms of menopause, as well as in the treatment of a variety of female diseases.
Separately, women note the convenience of using the product in the form of an ointment due to the presence of a special applicator.
Doctors' comments about Ovestin are also presented.
Doctors, for their part, report primarily on the high efficacy of the drug.
Less often, but still there are reviews of "Ovestin" in the form of a cream in the treatment of children. Parents separately note that in this case, you should strictly adhere to the doctor's recommendations. Otherwise, side effects may occur. In rare cases, women report a burning sensation in the first days of using local Ovestin preparations. However, this side effect quickly disappears.
It is important to remember that prescribe any medications, including hormonal ones, exclusively by a specialist.
We reviewed the instructions and reviews for Ovestin.