Medication "Nimesulide" instructions for use relates to non-steroidal anti-inflammatory drugs of the sulfonanilide class.
Indications for use are the following diseases: rheumatoid arthritis, osteoarthritis, arthrosis, myalgia, arthralgia, enthesopathy, bursitis, aldismenorrhea, fever and others.
In the course of studies, it was found that the drug "Nimesulide" (instructions for use also contains this information) is able to exert an analgesic effect quite quickly - literally within twenty minutes after ingestion, which is why it is so widely used to eliminate acute pain.
The pharmaceutical agent in question is taken orally at one hundred milligrams (one tablet or a similar amount in suspension) twice a day. Reception after a meal is recommended; drink the preparation with sufficient water. The medication is also used to prevent complications.
The drug "Nimesulide", instructions for use informs you should not take more than 400 milligrams per day. This amount is the maximum daily dose. The duration of the course of therapy is determined individually by the appropriate specialist. During the treatment period, it is necessary to monitor the functioning of the liver and kidneys of the patient.
When using the specified preparation in the form of a gel (one percent), it is applied to the affected areas with light massaging movements. Such a procedure should be carried out no more than four times a day. The gel is not used for applying compresses.
The medication "Nimesulide", the instructions for use contain this information, may cause some side effects. The occurrence of nausea, dizziness, headache, vomiting, gastralgia, heartburn, hematuria, oliguria, exanthema, ulceration of the mucous membranes, urticaria and anaphylactic shock was recorded. Also, the drug "Nimesulide" (suspension) can cause the following changes in blood characteristics : thrombocytopenia, agranulocytosis, leukopenia, anemia, an increase in the bleeding period.
Due to the external use of the medication, local irritation, erythema, itching, rash, peeling of those areas on which the gel was applied may develop.
In the annotation, it is especially noted that the appearance of any of the above side effects is a reason for the immediate cessation of taking the drug and going to the doctor.
The drug "Nimesulide" (powder), the instruction informs, is not prescribed during pregnancy, to patients under the age of twelve, in the presence of pathologies of a ulcerous nature and bleeding in the gastrointestinal tract, "aspirin" asthma, renal and liver failure. Suspension and gel in these cases is also not recommended.
Among the relative contraindications, ulcerative changes in the gastrointestinal tract, heart failure, arterial hypertension, the period of breastfeeding, as well as the presence of individual intolerance to other anti-inflammatory non-steroids are distinguished.
As indicated above, the drug "Nimesulide" is not prescribed during the period of gestation. At this time, taking the medication in question is absolutely contraindicated. This fact is explained by the fact that the drug can cause atony of the uterus of the expectant mother, as well as premature closure of the Batal duct in the fetus .
An overdose of this drug is accompanied by nausea, vomiting, pain in the abdomen, gastrointestinal bleeding, lethargy, drowsiness, acute renal failure, hypertension, anaphylactic shock or coma.
To eliminate the symptoms, gastric lavage should be carried out, activated charcoal or another sorbent should be taken.